Reduction of cancer risk by consumption of selenium-enriched plants: Enrichment of broccoli with selenium increases the anticarcinogenic properties of broccoli

Journal of Medicinal Food

Volumn 6, Issue 1, 2003, Pages 19-26

  Finley, John W ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

DIMETHYLBENZ[A]ANTHRACENE; GLUTATHIONE PEROXIDASE; SELENIUM;

ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOACCUMULATION; BRASSICA; BREAST CANCER; BROCCOLI; CANCER INCIDENCE; CANCER PREVENTION; CANCER RISK; COLON CANCER; DIETARY INTAKE; ENZYME ACTIVITY; GARLIC; NONHUMAN; NUTRIENT; PRIORITY JOURNAL; RAT; TUMOR VOLUME;

ALLIUM SATIVUM; ANIMALIA; BRASSICA; BRASSICA OLERACEA VAR. BOTRYTIS;

EID: 0037951520     PISSN: 1096620X     EISSN: None     Source Type: Journal    
DOI: 10.1089/109662003765184714     Document Type: Article

References (47)

1. Talalay P, Fahey JW: Phytochemicals from cruciferous plants protect against cancer by modulating carcinogen metabolism. J Nutr 2001;131:3027S-3033S.
2. Clark LC, Combs G, Turnbull B, et al.: Effects of selenium supplementation for cancer prevention in patients with carcinoma of the skin. JAMA 1996;276: 1957-1963.
3. Läuchli, A: Selenium in plants: Uptake, functions and environmental toxicity. Bot Acta 1993;106:455-468.
4. Cai X-J, Block E, Uden PC, et al.: Alium chemistry: Identification of selenoamino acids in ordinary and selenium-enriched garlic, onion, and broccoli using gas chromatography with atomic emission detection. J Agric Food Chem 1995;43:1754-1757.
5. Schwarz K, Foltz C: Selenium as integral part of factor 3 against dietary necrotic liver degeneration. J Am Chem Soc 1957;79:3292-3293.
6. Burk R, Hill K: Regulation of selenoproteins. In: Annual Review of Nutrition, (Olson R, Bier D, McCormick D, eds.), Annual Reviews, Palo Alto, CA, 1993, pp 65-81.
7. Beck M, Kolbeck P, Rohr L, et al.: Benign human enterovirus becomes virulent in selenium-deficient mice. J Med Virol 1995;43:166-170.
8. Finley J, Penland J: Adequacy or deprivation of dietary selenium in healthy men: Clinical and psychological findings. J Trace Elem Exp Med 1998;11:11-27.
9. Levander OA: Selenium and sulfur in antioxidant protective systems: Relationships with vitamin E and malaria. Proc Soc Exp Biol Med 1992;200:255-259.
10. Christensen M, Pusey N: Binding of nuclear proteins to transcription regulatory elements in selenium deficiency. Biochim Biophys Acta 1994;1225:338-341.
11. Brigelius-Flohe R: Tissue-specific functions of individual glutathione peroxidases. Free Radic Biol Med 1999;27:951-965.
12. Blot W, Li J, Taylor P, et al.: Nutrition intervention trials in Linxian China: Supplementation with specific vitamin/mineral combinations, cancer incidence and disease specific mortality in the general population. J Natl Cancer Inst 1993;85:1483-1492.
13. Yoshizawa K, Willett WC, Morris SJ, et al.: Study of prediagnostic selenium level in toenails and the risk of advanced prostate cancer. J Natl Cancer Inst 1998;90: 1219-1224.
14. Rayman MP: Dietary selenium: Time to act - Low bioavailability in Britain and Europe could be contributing to cancers, cardiovascular disease, and subfertility. Br Med J 1997;314:387-388.
15. Ganther HE, Lawrence JR: Chemical transformations of selenium in living organisms: Improved forms of selenium for cancer prevention. Tetrahedron 1997;53: 12299-12310.
16. El-Bayoumy K, Upadhyaya P, Chae Y, et al.: Chemoprevention of cancer by organo-selenium compounds. J Cell Biochem 1995;22:92-100.
17. Whanger PD: Metabolism of selenium in humans. J Trace Elem Exp Med 1998;11:227-240.
18. Whanger P, Butler J: Effects of various dietary levels of selenium as selenite or selenomethionine on tissue selenium levels and glutathione peroxidase activity in rats. J Nutr 1988;118:846-852.
19. Ip C, Ganther H: Activity of methylated forms of selenium in cancer prevention. Cancer Res 1996;50: 1206-1211.
20. Finley J, Matthys L, Shuler T, Korynta E: Selenium content of foods purchased in North Dakota. Nutr Res 1996;16:723-728.
21. Olson OE, Novacek E, Whitehead E, Palmer I: Investigations on selenium in wheat. J Trace Elem Electrolytes Health Dis 1970;7:107-108.
22. Finley J: Does selenium accumulation in meat confer a health benefit to the consumer? Proc Am Soc Animal Sci 1999; available at: http://www.asas.org/jas/symposia/proceedings/0911.pdf12/00.
23. Ip C, Birringer M, Block E, et al.: Chemical speciation influences comparative activity of selenium-enriched garlic and yeast in mammary cancer prevention. J Agric Food Chem 2000;48:2062-2670.
24. Wang Y, Bock A, Neuhierl B: Acquisition of selenium tolerance by a selenium non-accumulating Astragalus species via selection. Biofactors 1999;9:3-10.
25. Neuhierl B, Bock A: On the mechanism of selenium tolerance in selenium-accumulating plants: Purification and characterization of a specific selenocysteine methyltransferase from cultured cells of Astragalus bisculatus. Eur J Biochem 2000;239:235-238.
26. Finley J: Selenium from broccoli is metabolized differently than Se from selenite, selenate or selenomethionine. J Agric Food Chem 1998;46:3702-3707.
27. Roberge MT, Borgerding AJ, Finley JW: Extraction conditions affect the speciation of organoselenium compounds in solutions used as receiving phases for lyophilized high selenium broccoli. Proc 57th Northwest Regional Meeting Am Chem Soc, 2002; Abstr. #53.
28. Finley J: The retention and distribution by healthy young men of stable isotopes of selenium consumed as selenite, selenate or hydroponically-grown broccoli are dependent on the chemical form. J Nutr 1999;129:865-871.
29. Dong Y, Lisk D, Block E, Ip C: Characterization of the biological activity of gamma-glutamyl-Se-methylselenocysteine: A novel, naturally occurring anticancer agent from garlic. Cancer Res 2001;61:2923-2928.
30. Ip C, Ganther HE: Activity of methylated forms of selenium in cancer prevention. Cancer Res 1990;50: 1206-1211.
31. Ip C, Lisk D: Characterization of tissue selenium profiles and anticarcinogenic responses in rats fed natural sources of selenium-rich products. Carcinogenesis 1994;15:573-576.
32. Ip C, Lisk D: Enrichment of selenium in allium vegetables for cancer prevention. Carcinogensis 1994;9: 1881-1885.
33. Ip C, Lisk J, Stoewsand G: Mammary cancer prevention by regular garlic and selenium enriched garlic. Nutr Cancer 1992;17:279-286.
34. Ip C, Lisk DJ: Efficacy of cancer prevention by highselenium garlic is primarily dependent on the action of selenium. Carcinogenesis 1995;16:2649-2652.
35. Lu J, Pei H, Ip C, et al.: Effect of an aqueous extract of selenium-enriched garlic on in vitro markers and in vivo efficacy of cancer prevention. Carcinogenesis 1996;17:1903-1907.
36. Verhoeven DT, Goldbohm RA, van Poppel G, Verhagen H, van den Brandt PA: Epidemiological studies on brassica vegetables and cancer risk. Cancer Epidemiol Biomarkers Prev 1996;5:733-748.
37. Michaud DS, Spiegelman D, Clinton SK, et al.: Fruit and vegetable intake and incidence of bladder cancer in a male prospective cohort. J Natl Cancer Inst 1999; 91:605-613.
38. Keck AS, Finley JW: Bioactive components of cruciferous vegetables and their mechanism of action in cancer protection. Integr Cancer Ther (Submitted).
39. Irion CW: Growing alliums and brassicas in seleniumenriched soils increases their anticarcinogenic potentials. Med Hypotheses 1999;53:232-235.
40. Finley JW, Grusak MA, Keck A-S, Gregoire BR: Bioavailability of selenium from meat and broccoli as determined by retention and distribution of Se75. FASEB J 2003;17:A1136.
41. Feng Y, Finley J, Davis C, et al.: Dietary selenium reduces the formation of aberrant crypts in rats administered 3,2′-dimethyl-4-aminobiphenyl. Toxicol Appl Pharmacol 1999;157:36-42.
42. Finley JW, Davis C, Feng Y: Selenium from high-selenium broccoli protects rats from colon cancer. J Nutr 2000;130:2384-2389.
43. Finley JW, Ip C, Lisk DJ, et al.: Cancer-protective properties of high-selenium broccoli. J Agric Food Chem 2001;49:2679-2683.
44. Davis C, Zeng H, Finley J: Selenium-enriched broccoli decreases intestinal tumorogenesis in multiple intestinal neoplasia mice. J Nutr 2002;132:307-309.
45. Banuelos G, Ajwa H, Wu L, et al.: Selenium-induced growth reduction in Brassica land races considered for phytoremediation. Ecotoxicol Environ Safety 1997;36: 282-287.
46. Das KC, Guo XL, White CW: Induction of thioredoxin and thioredoxin reductase gene expression in lungs of newborn primates by oxygen. Am J Physiol 1999; 276:L530-L539.
47. Hintze KJ, Wald KA, Jeffery EH, Finley JW: Evidence for the transcriptional regulation of thioredoxin reductase by an antioxidant responsive element. Biochem Biophys Res Commun (Submitted).