Synthesis of (Z)-(2,3-bis-Hydroxymethyl)methylenecyclopropane analogues of purine nucleosides

Nucleosides, Nucleotides and Nucleic Acids

Volumn 22, Issue 3, 2003, Pages 265-274

  Chen, Xinchao ^a   Matsumi, Shintaro ^b   Mitsuya, Hiroaki ^b,c   Zemlicka, Jiri ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c KUMAMOTO UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

Alkylation elimination; Anti HIV agents; Methylenecyclopropanes; Nucleoside analogues

Indexed keywords

(2,3 BIS HYDROXYMETHYL)METHYLENECYCLOPROPANE DERIVATIVE; 9 [2,3 BIS(HYDROXYMETHYL)CYCLOPROPYLIDENEMETHYL]ADENINE; PURINE NUCLEOSIDE DERIVATIVE; UNCLASSIFIED DRUG;

ALKYLATION; ANTIVIRAL ACTIVITY; ARTICLE; DEACETYLATION; DEPROTECTION REACTION; DRUG ACETYLATION; DRUG SYNTHESIS; EPIMERIZATION; EPSTEIN BARR VIRUS; HEPATITIS B VIRUS; HERPES SIMPLEX VIRUS 1; HERPES SIMPLEX VIRUS 2; HUMAN CYTOMEGALOVIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; REACTION ANALYSIS; VARICELLA ZOSTER VIRUS;

ANTI-HIV AGENTS; CYCLOPROPANES; HIV-1; MODELS, CHEMICAL; MOLECULAR STRUCTURE; PURINE NUCLEOSIDES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

CYTOMEGALOVIRUS; HEPATITIS B VIRUS; HUMAN HERPESVIRUS 1; HUMAN HERPESVIRUS 2; HUMAN HERPESVIRUS 3; HUMAN HERPESVIRUS 4; HUMAN HERPESVIRUS 5; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; SIMPLEXVIRUS;

EID: 0037946820     PISSN: 15257770     EISSN: None     Source Type: Journal    
DOI: 10.1081/NCN-120021426     Document Type: Article

References (17)

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