In vitro phonophoresis of mannitol, oestradiol and hydrocortisone across human and hairless mouse skin

International Journal of Pharmaceutics

Volumn 165, Issue 2, 1998, Pages 169-174

  Machet, L ^a,b   Cochelin, N ^a,b   Patat, F ^a   Arbeille, B ^a   Machet, M C ^b   Lorette, G ^b   Vaillant, L ^a,b  

^a UNIVERSITÉ DE TOURS   (France)

^b SERVICE DE DERMATOLOGIE   (France)

Author keywords

Electron microscopy; Hairless mouse skin; Human skin; Percutaneous administration; Phonophoresis; Ultrasound

Indexed keywords

ESTRADIOL; HYDROCORTISONE; MANNITOL;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIFFUSION; DRUG ABSORPTION; DRUG DIFFUSION; ELECTRON MICROSCOPY; HUMAN; HUMAN TISSUE; IN VITRO STUDY; LIQUID SCINTILLATION COUNTING; NONHUMAN; NUDE MOUSE; PHYSICAL MEDICINE; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SKIN; SKIN ABSORPTION; STRATUM CORNEUM; TRANSDERMAL DRUG ADMINISTRATION; ULTRASOUND;

EID: 0032516231     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(97)00377-3     Document Type: Article

References (13)

1. Benson H.E.A., McElnay J.C., Marland R. Use of ultrasound to enhance percutaneous absorption of benzydamine. Phys. Ther. 69:1989;113-118.
2. Bommannan D., Menon G.K., Okuyama K., Elias P.M., Guy R.H. Sonophoresis. I. The use of high-frequency ultrasound to enhance transdermal drug delivery. Pharm. Res. 9:1992;559-563.
3. Bronaugh R.L., Stewart R.F., Simon M. Methods for in vitro percutaneous absorption studies. Vll: use of excised human skin. J. Pharm. Sci. 75:1986;1094-1097.
4. Brucks R., Nanavaty M., Jung D., Siegel F. The effect of ultrasound on the in vitro penetration of ibuprofen through human epidermis. Pharm. Res. 6:1989;697-701.
5. Byl N.N. The use of ultrasound as an enhancer for transcutaneous drug delivery: phonophoresis. Phys. Ther. 75:1995;539-553.
6. Machet L., Pinton J., Patat F., Arbeille B., Pourcelot L., Vaillant L. In vitro phonophoresis of digoxin across hairless mice and human skin: thermal effect of ultrasound. Int. J. Pharm. 133:1996;39-45.
7. Menon G.K., Bommannan D.B., Elias P.M. High frequency sonophoresis: permeation pathways and structural basis for enhanced permeability. Skin Pharmacol. 7:1994;130-139.
8. Mitragori S., Edwards D.A., Blankstein D., Langer R. A mechanistic study of ultrasonically-enhanced transdermal drug delivery. J. Pharm. Sci. 84:1995;697-706.
9. Mitragori S., Blankstein D., Langer R. Transdermal drug delivery using lowfrequency sonophoresis. Pharm. Res. 13:1996;411-420.
10. Pelucio-Lopes C., Machet L., Vaillant L., Patat F., Letiecq M., Furet Y., Lorette G. Phonophoresis of azidothymidine (AZT) ex vivo across human and hairless mice skin. Int. J. Pharm. 90:1993;1-10.
11. Simonin J.P. On the mechanisms of in vitro and in vivo phonophoresis. J. Control. Release. 1:1995;125-141.
12. Ueda H., Ogihara M., Sugibayashi K., Morimoto Y. Difference in the enhancing effects of ultrasound on the skin permeation of polar and non-polar drugs. Chem. Pharm. Bull. 44:1996;1973-1976.
13. Williams A.R. Phonophoresis: an in vivo evaluation using three topical anaesthetic preparations. Ultrasonics. 28:1990;137-141.