메뉴 건너뛰기




Volumn 22, Issue 12, 2003, Pages 3113-3121

A novel boundary element may facilitate independent gene regulation in the Antennapedia complex of Drosophila

Author keywords

Boundary; Enhancer promoter specificity; Ftz; HOM Hox; Insulator; Scr

Indexed keywords

ANTENNAPEDIA COMPLEX; ARTICLE; CHROMATIN; DROSOPHILA; EMBRYO; ENHANCER REGION; FTZ GENE; GENE CONTROL; GENE LOCUS; GENETIC CONSERVATION; HOMEOBOX; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; SCR GENE; SF1 GENE;

EID: 0037938506     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdg297     Document Type: Article
Times cited : (90)

References (42)
  • 2
    • 0034954885 scopus 로고    scopus 로고
    • The MCP silencer of the Drosophila Abd-B gene requires both Pleiohomeotic and GAGA factor for the maintenance of repression
    • Busturia, A., Lloyd, A., Bejarano, F., Zavortink, M., Xin, H. and Sakonju, S. (2001) The MCP silencer of the Drosophila Abd-B gene requires both Pleiohomeotic and GAGA factor for the maintenance of repression. Development, 128, 2163-2173.
    • (2001) Development , vol.128 , pp. 2163-2173
    • Busturia, A.1    Lloyd, A.2    Bejarano, F.3    Zavortink, M.4    Xin, H.5    Sakonju, S.6
  • 3
    • 0030998714 scopus 로고    scopus 로고
    • The gypsy insulator can function as a promoter-specific silencer in the Drosophila embryo
    • Cai, H.N. and Levine, M. (1997) The gypsy insulator can function as a promoter-specific silencer in the Drosophila embryo. EMBO J., 16, 1732-1741.
    • (1997) EMBO J. , vol.16 , pp. 1732-1741
    • Cai, H.N.1    Levine, M.2
  • 4
    • 0035910516 scopus 로고    scopus 로고
    • Effects of cis arrangement of chromatin insulators on enhancer-blocking activity
    • Cai, H.N. and Shen, P. (2001) Effects of cis arrangement of chromatin insulators on enhancer-blocking activity. Science, 291, 493-495.
    • (2001) Science , vol.291 , pp. 493-495
    • Cai, H.N.1    Shen, P.2
  • 5
    • 0035173960 scopus 로고    scopus 로고
    • Genomic context modulates insulator activity through promoter competition
    • Cai, H.N., Zhang, Z., Adams, J.R. and Shen, P. (2001) Genomic context modulates insulator activity through promoter competition. Development, 128, 4339-4347.
    • (2001) Development , vol.128 , pp. 4339-4347
    • Cai, H.N.1    Zhang, Z.2    Adams, J.R.3    Shen, P.4
  • 6
    • 0037047146 scopus 로고    scopus 로고
    • Promoter-proximal tethering elements regulate enhancer-promoter specificity in the Drosophila Antennapedia complex
    • Calhoun, V.C., Stathopoulos, A. and Levine, M. (2002) Promoter-proximal tethering elements regulate enhancer-promoter specificity in the Drosophila Antennapedia complex. Proc. Natl Acad. Sci. USA, 99, 9243-9247.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 9243-9247
    • Calhoun, V.C.1    Stathopoulos, A.2    Levine, M.3
  • 7
    • 0028365098 scopus 로고
    • Dax, a locust Hox gene related to fushi-tarazu but showing no pair-rule expression
    • Dawes, R., Dawson, I., Falciani, F., Tear, G. and Akam, M. (1994) Dax, a locust Hox gene related to fushi-tarazu but showing no pair-rule expression. Development, 120, 1561-1572.
    • (1994) Development , vol.120 , pp. 1561-1572
    • Dawes, R.1    Dawson, I.2    Falciani, F.3    Tear, G.4    Akam, M.5
  • 9
    • 0029826485 scopus 로고    scopus 로고
    • Organization of the Hox gene cluster in the grasshopper, Schistocerca gregaria
    • Ferrier, D.E. and Akam, M. (1996) Organization of the Hox gene cluster in the grasshopper, Schistocerca gregaria. Proc. Natl Acad. Sci. USA, 93, 13024-13029.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 13024-13029
    • Ferrier, D.E.1    Akam, M.2
  • 10
    • 0026654757 scopus 로고
    • Individual stage selector element mutations lead to reciprocal changes in beta- vs epsilon-globin gene transcription: Genetic confirmation of promoter competition during globin gene switching
    • Foley, K.P. and Engel, J.D. (1992) Individual stage selector element mutations lead to reciprocal changes in beta- vs epsilon-globin gene transcription: genetic confirmation of promoter competition during globin gene switching. Genes Dev., 6, 730-744.
    • (1992) Genes Dev. , vol.6 , pp. 730-744
    • Foley, K.P.1    Engel, J.D.2
  • 11
    • 0027462572 scopus 로고
    • The bluetail transposon: Evidence for independent cis-regulatory domains and domain boundaries in the bithorax complex
    • Galloni, M., Gyurkovics, H., Schedl, P. and Karch, F. (1993) The bluetail transposon: evidence for independent cis-regulatory domains and domain boundaries in the bithorax complex. EMBO J., 12, 1087-1097.
    • (1993) EMBO J. , vol.12 , pp. 1087-1097
    • Galloni, M.1    Gyurkovics, H.2    Schedl, P.3    Karch, F.4
  • 12
    • 0035671406 scopus 로고    scopus 로고
    • Chromatin insulators and boundaries: Effects on transcription and nuclear organization
    • Gerasimova, T.I. and Corces, V.G. (2001) Chromatin insulators and boundaries: effects on transcription and nuclear organization. Annu. Rev. Genet., 35, 193-208.
    • (2001) Annu. Rev. Genet. , vol.35 , pp. 193-208
    • Gerasimova, T.I.1    Corces, V.G.2
  • 13
    • 0023445598 scopus 로고
    • Separate regulatory elements are responsible for the complex pattern of tissue-specific and developmental transcription of the yellow locus in Drosophila melanogaster
    • Geyer, P.K. and Corces, V.G. (1987) Separate regulatory elements are responsible for the complex pattern of tissue-specific and developmental transcription of the yellow locus in Drosophila melanogaster. Genes Dev., 1, 996-1004.
    • (1987) Genes Dev. , vol.1 , pp. 996-1004
    • Geyer, P.K.1    Corces, V.G.2
  • 14
    • 0025353653 scopus 로고
    • A new homeotic mutation in the Drosophila bithorax complex removes a boundary separating two domains of regulation
    • Gyurkovics, H., Gausz, J., Kummer, J. and Karch, F. (1990) A new homeotic mutation in the Drosophila bithorax complex removes a boundary separating two domains of regulation. EMBO J., 9, 2579-2585.
    • (1990) EMBO J. , vol.9 , pp. 2579-2585
    • Gyurkovics, H.1    Gausz, J.2    Kummer, J.3    Karch, F.4
  • 15
    • 0030463741 scopus 로고    scopus 로고
    • Fab-7 functions as a chromatin domain boundary to ensure proper segment specification by the Drosophila bithorax complex
    • Hagstrom, K., Muller, M. and Schedl, P. (1996) Fab-7 functions as a chromatin domain boundary to ensure proper segment specification by the Drosophila bithorax complex. Genes Dev., 10, 3202-3215.
    • (1996) Genes Dev. , vol.10 , pp. 3202-3215
    • Hagstrom, K.1    Muller, M.2    Schedl, P.3
  • 16
    • 0021804649 scopus 로고
    • Spatially regulated expression of homeotic genes in Drosophila
    • Harding, K., Wedeen, C., McGinnis, W. and Levine, M. (1985) Spatially regulated expression of homeotic genes in Drosophila. Science, 229, 1236-1242.
    • (1985) Science , vol.229 , pp. 1236-1242
    • Harding, K.1    Wedeen, C.2    McGinnis, W.3    Levine, M.4
  • 17
    • 0026728302 scopus 로고
    • The dorsal gradient morphogen regulates stripes of rhomboid expression in the presumptive neuroectoderm of the Drosophila embryo
    • Ip, Y.T., Park, R.E., Kosman, D., Bier, E. and Levine, M. (1992) The dorsal gradient morphogen regulates stripes of rhomboid expression in the presumptive neuroectoderm of the Drosophila embryo. Genes Dev., 6, 1728-1739.
    • (1992) Genes Dev. , vol.6 , pp. 1728-1739
    • Ip, Y.T.1    Park, R.E.2    Kosman, D.3    Bier, E.4    Levine, M.5
  • 18
    • 0033667672 scopus 로고    scopus 로고
    • Targeted inversion of a polar silencer within the HoxD complex re-allocates domains of enhancer sharing
    • Kmita, M., Kondo, T. and Duboule, D. (2000) Targeted inversion of a polar silencer within the HoxD complex re-allocates domains of enhancer sharing. Nat. Genet., 26, 451-454.
    • (2000) Nat. Genet. , vol.26 , pp. 451-454
    • Kmita, M.1    Kondo, T.2    Duboule, D.3
  • 19
    • 0036340406 scopus 로고    scopus 로고
    • GAGA factor and the TFIID complex collaborate in generating an open chromatin structure at the Drosophila melanogaster hsp26 promoter
    • Leibovitch, B.A., Lu, Q., Benjamin, L.R., Liu, Y., Gilmour, D.S. and Elgin, S.C. (2002) GAGA factor and the TFIID complex collaborate in generating an open chromatin structure at the Drosophila melanogaster hsp26 promoter. Mol. Cell. Biol., 22, 6148-6157.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 6148-6157
    • Leibovitch, B.A.1    Lu, Q.2    Benjamin, L.R.3    Liu, Y.4    Gilmour, D.S.5    Elgin, S.C.6
  • 20
    • 0018240421 scopus 로고
    • A gene complex controlling segmentation in Drosophila
    • Lewis, E.B. (1978) A gene complex controlling segmentation in Drosophila. Nature, 276, 565-570.
    • (1978) Nature , vol.276 , pp. 565-570
    • Lewis, E.B.1
  • 21
    • 0035908952 scopus 로고    scopus 로고
    • Drosophila fushi tarazu: A gene on the border of homeotic function
    • Lohr, U., Yussa, M. and Pick, L. (2001) Drosophila fushi tarazu: a gene on the border of homeotic function. Curr. Biol., 11, 1403-1412.
    • (2001) Curr. Biol. , vol.11 , pp. 1403-1412
    • Lohr, U.1    Yussa, M.2    Pick, L.3
  • 22
    • 0037007221 scopus 로고    scopus 로고
    • GAGA can mediate enhancer function in trans by linking two separate DNA molecules
    • Mahmoudi, T., Katsani, K.R. and Verrijzer, C.P. (2002) GAGA can mediate enhancer function in trans by linking two separate DNA molecules. EMBO J., 21, 1775-1781.
    • (2002) EMBO J. , vol.21 , pp. 1775-1781
    • Mahmoudi, T.1    Katsani, K.R.2    Verrijzer, C.P.3
  • 23
    • 0025093897 scopus 로고
    • Regulation of the segmentation gene fushi tarazu has been functionally conserved in Drosophila
    • Maier, D., Preiss, A. and Powell, J.R. (1990) Regulation of the segmentation gene fushi tarazu has been functionally conserved in Drosophila. EMBO J., 9, 3957-3966.
    • (1990) EMBO J. , vol.9 , pp. 3957-3966
    • Maier, D.1    Preiss, A.2    Powell, J.R.3
  • 24
    • 0027503502 scopus 로고
    • Conservation and change of the developmentally crucial fushi tarazu gene in Drosophila
    • Maier, D., Sperlich, D. and Powell, J.R. (1993) Conservation and change of the developmentally crucial fushi tarazu gene in Drosophila. J. Mol. Evol., 36, 315-326.
    • (1993) J. Mol. Evol. , vol.36 , pp. 315-326
    • Maier, D.1    Sperlich, D.2    Powell, J.R.3
  • 25
    • 0029973108 scopus 로고    scopus 로고
    • Promoter specificity mediates the independent regulation of neighboring genes
    • Merli, C., Bergstrom, D.E., Cygan, J.A. and Blackman, R.K. (1996) Promoter specificity mediates the independent regulation of neighboring genes. Genes Dev., 10, 1260-1270.
    • (1996) Genes Dev. , vol.10 , pp. 1260-1270
    • Merli, C.1    Bergstrom, D.E.2    Cygan, J.A.3    Blackman, R.K.4
  • 26
    • 6844240870 scopus 로고    scopus 로고
    • Chromatin of domain boundaries in the Bithorax complex
    • Mihaly, J. et al. (1998) Chromatin of domain boundaries in the Bithorax complex. Cell. Mol. Life Sci., 54, 60-70.
    • (1998) Cell. Mol. Life Sci. , vol.54 , pp. 60-70
    • Mihaly, J.1
  • 27
    • 0035146753 scopus 로고    scopus 로고
    • The iab-7 polycomb response element maps to a nucleosome-free region of chromatin and requires both GAGA and pleiohomeotic for silencing activity
    • Mishra, R.K., Mihaly, J., Barges, S., Spierer, A., Karch, F., Hagstrom, K., Schweinsberg, S.E. and Schedl, P. (2001) The iab-7 polycomb response element maps to a nucleosome-free region of chromatin and requires both GAGA and pleiohomeotic for silencing activity. Mol. Cell. Biol., 21, 1311-1318.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 1311-1318
    • Mishra, R.K.1    Mihaly, J.2    Barges, S.3    Spierer, A.4    Karch, F.5    Hagstrom, K.6    Schweinsberg, S.E.7    Schedl, P.8
  • 30
    • 0032213217 scopus 로고    scopus 로고
    • GAGA mediates the enhancer blocking activity of the eve promoter in the Drosophila embryo
    • Ohtsuki, S. and Levine, M. (1998) GAGA mediates the enhancer blocking activity of the eve promoter in the Drosophila embryo. Genes Dev., 12, 3325-3330.
    • (1998) Genes Dev. , vol.12 , pp. 3325-3330
    • Ohtsuki, S.1    Levine, M.2
  • 31
    • 0032519586 scopus 로고    scopus 로고
    • Different core promoters possess distinct regulatory activities in the Drosophila embryo
    • Ohtsuki, S., Levine, M. and Cai, H.N. (1998) Different core promoters possess distinct regulatory activities in the Drosophila embryo. Genes Dev., 12, 547-556.
    • (1998) Genes Dev. , vol.12 , pp. 547-556
    • Ohtsuki, S.1    Levine, M.2    Cai, H.N.3
  • 32
    • 0025195639 scopus 로고
    • Analysis of the ftz upstream element: Germ layer-specific enhancers are independently autoregulated
    • Pick, L., Schier, A., Affolter, M., Schmidt-Glenewinkel, T. and Gehring, W.J. (1990) Analysis of the ftz upstream element: germ layer-specific enhancers are independently autoregulated. Genes Dev., 4, 1224-1239.
    • (1990) Genes Dev. , vol.4 , pp. 1224-1239
    • Pick, L.1    Schier, A.2    Affolter, M.3    Schmidt-Glenewinkel, T.4    Gehring, W.J.5
  • 33
    • 0035476530 scopus 로고    scopus 로고
    • Establishment of Polycomb silencing requires a transient interaction between PC and ESC
    • Poux, S., Melfi, R. and Pirrotta, V. (2001) Establishment of Polycomb silencing requires a transient interaction between PC and ESC. Genes Dev., 15, 2509-2514.
    • (2001) Genes Dev. , vol.15 , pp. 2509-2514
    • Poux, S.1    Melfi, R.2    Pirrotta, V.3
  • 34
    • 0019945644 scopus 로고
    • Genetic transformation of Drosophila with transposable element vectors
    • Rubin, G.M. and Spradling, A.C. (1982) Genetic transformation of Drosophila with transposable element vectors. Science, 218, 348-353.
    • (1982) Science , vol.218 , pp. 348-353
    • Rubin, G.M.1    Spradling, A.C.2
  • 35
    • 0026744792 scopus 로고
    • Regulation of even-skipped stripe 2 in the Drosophila embryo
    • Small, S., Blair, A. and Levine, M. (1992) Regulation of even-skipped stripe 2 in the Drosophila embryo. EMBO J., 11, 4047-4057.
    • (1992) EMBO J. , vol.11 , pp. 4047-4057
    • Small, S.1    Blair, A.2    Levine, M.3
  • 36
    • 0024319520 scopus 로고
    • A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback
    • Tautz, D. and Pfeifle, C. (1989) A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback. Chromosoma, 98, 81-85.
    • (1989) Chromosoma , vol.98 , pp. 81-85
    • Tautz, D.1    Pfeifle, C.2
  • 37
    • 0034704767 scopus 로고    scopus 로고
    • Evidence for the derivation of the Drosophila fushi tarazu gene from a Hox gene orthologous to lophotrochozoan Lox5
    • Telford, M.J. (2000) Evidence for the derivation of the Drosophila fushi tarazu gene from a Hox gene orthologous to lophotrochozoan Lox5. Curr. Biol., 10, 349-352.
    • (2000) Curr. Biol. , vol.10 , pp. 349-352
    • Telford, M.J.1
  • 38
    • 0037418234 scopus 로고    scopus 로고
    • Genomewide analysis of Drosophila GAGA factor target genes reveals context-dependent DNA binding
    • vanSteensel, B., Delrow, J. and Bussemaker, H.J. (2003) Genomewide analysis of Drosophila GAGA factor target genes reveals context-dependent DNA binding. Proc. Natl Acad. Sci. USA, 100, 2580-2585.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 2580-2585
    • VanSteensel, B.1    Delrow, J.2    Bussemaker, H.J.3
  • 39
    • 0036467996 scopus 로고    scopus 로고
    • Insulators: Many functions, many mechanisms
    • West, A.G., Gaszner, M. and Felsenfeld, G. (2002) Insulators: many functions, many mechanisms. Genes Dev., 16, 271-288.
    • (2002) Genes Dev. , vol.16 , pp. 271-288
    • West, A.G.1    Gaszner, M.2    Felsenfeld, G.3
  • 40
    • 0033544703 scopus 로고    scopus 로고
    • A novel cis-regulatory element, the PTS, mediates an anti-insulator activity in the Drosophila embryo
    • Zhou, J. and Levine, M. (1999) A novel cis-regulatory element, the PTS, mediates an anti-insulator activity in the Drosophila embryo. Cell, 99, 567-575.
    • (1999) Cell , vol.99 , pp. 567-575
    • Zhou, J.1    Levine, M.2
  • 41
    • 0030452423 scopus 로고    scopus 로고
    • The Fab-7 element of the bithorax complex attenuates enhancer-promoter interactions in the Drosophila embryo
    • Zhou, J., Barolo, S., Szymanski, P. and Levine, M. (1996) The Fab-7 element of the bithorax complex attenuates enhancer-promoter interactions in the Drosophila embryo. Genes Dev., 10, 3195-3201.
    • (1996) Genes Dev. , vol.10 , pp. 3195-3201
    • Zhou, J.1    Barolo, S.2    Szymanski, P.3    Levine, M.4
  • 42
    • 0032784608 scopus 로고    scopus 로고
    • Characterization of the transvection mediating region of the abdominal-B locus in Drosophila
    • Zhou, J., Ashe, H., Burks, C. and Levine, M. (1999) Characterization of the transvection mediating region of the abdominal-B locus in Drosophila. Development, 126, 3057-3065.
    • (1999) Development , vol.126 , pp. 3057-3065
    • Zhou, J.1    Ashe, H.2    Burks, C.3    Levine, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.