Salicylate induces tinnitus through activation of cochlear NMDA receptors

Journal of Neuroscience

Volumn 23, Issue 9, 2003, Pages 3944-3952

  Guitton, Matthieu J ^a   Caston, Jean ^b   Ruel, Jérôme ^a   Johnson, Randolph M ^c   Pujol, Rémy ^a   Puel, Jean Luc ^a  

^a INSERM   (France)

^b UNIVERSITÉ DE ROUEN   (France)

^c DURECT Corporation   (United States)

Author keywords

Behavioral model; Cyclooxygenase pathway; Local therapy; NMDA receptor; Salicylate; Tinnitus

Indexed keywords

ARACHIDONIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PROSTAGLANDIN SYNTHASE; SALICYLIC ACID DERIVATIVE; MEFENAMIC ACID; PROSTAGLANDIN SYNTHASE INHIBITOR;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARACHIDONIC ACID METABOLISM; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INHIBITION; FEMALE; HEARING; HORMONE RECEPTOR INTERACTION; MOTOR ACTIVITY; NEUROPHARMACOLOGY; NONHUMAN; OTOTOXICITY; PERCEPTION; PRIORITY JOURNAL; RAT; TASK PERFORMANCE; TINNITUS; ACTION POTENTIAL; ANIMAL; CHEMICALLY INDUCED DISORDER; COCHLEA; COCHLEAR NERVE; CONDITIONED REFLEX; DISEASE MODEL; DRUG EFFECT; ELECTRIC SHOCK; ELECTRODE; LABORATORY DIAGNOSIS; LONG EVANS RAT; METABOLISM; PATHOPHYSIOLOGY; SPONTANEOUS OTOACOUSTIC EMISSION;

ACTION POTENTIALS; ANIMALS; BEHAVIOR, ANIMAL; COCHLEA; COCHLEAR NERVE; CONDITIONING, CLASSICAL; CYCLOOXYGENASE INHIBITORS; DISEASE MODELS, ANIMAL; ELECTRODES, IMPLANTED; ELECTROSHOCK; FALSE POSITIVE REACTIONS; FEMALE; MEFENAMIC ACID; OTOACOUSTIC EMISSIONS, SPONTANEOUS; RATS; RATS, LONG-EVANS; RECEPTORS, N-METHYL-D-ASPARTATE; SALICYLATES; TINNITUS;

EID: 0037868895     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.23-09-03944.2003     Document Type: Article

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