Molecularly imprinted cyclodextrin polymers as stationary phases of high performance liquid chromatography

Polymer Journal

Volumn 35, Issue 5, 2003, Pages 440-445

  Hishiya, Takayuki ^a,c   Asanuma, Hiroyuki ^a,b   Komiyama, Makoto ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c KYUSHU UNIVERSITY   (Japan)

Author keywords

Cyclodextrin; High performance liquid chromatography (HPLC); Molecular imprinting; Stationary phase; Steroids

Indexed keywords

AGENTS; BINDING ENERGY; CHEMICAL ANALYSIS; CHOLESTEROL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROPHOBICITY; MOLECULAR STRUCTURE;

MOLECULARLY IMPRINTED CYCLODEXTRIN POLYMERS; SELECTIVE RECOGNITION; STEROIDS;

ORGANIC POLYMERS;

EID: 0037774583     PISSN: 00323896     EISSN: None     Source Type: Journal    
DOI: 10.1295/polymj.35.440     Document Type: Article

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37. At a higher ratio of water in the eluent, peaks were too broadened to determine retention times percisely.
38. Present imprinting made the peak broadened as observed in the conventional imprinting. But, it did not affect the measuement of retention times for the guests at all.
39. High hydrophobicity of cholesterol compared with other steroids also contributed to this remarkable imprinting effect.
40. NOE was observed between CyD molecules and the guest (p-terphenyl) in DMSO, indicating that complex was formed during polymerization. UV spectrum was also changed (peak shift was observed) on addition of β-CyD in DMSO. This method has an advantage in preparing artificial receptors for the chemicals sparingly soluble in water.
41. Phenoxathiin is similar in structure to dioxin compounds except for the lack of halogen atoms.