Expression and regulation of voltage-gated sodium channel β1 subunit protein in human gliosis-associated pathologies

Acta Neuropathologica

Volumn 105, Issue 5, 2003, Pages 515-523

  Aronica, Eleonora ^a,b   Troost, Dirk ^a,b   Rozemuller, Annemieke J ^a   Yankaya, Bulent ^a   Jansen, Gerard H ^c   Isom, Lori L ^d   Gorter, Jan A ^b,e  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b STICHTING EPILEPSIE INSTELLINGEN NEDERLAND SEIN   (Netherlands)

^c UNIVERSITY OF OTTAWA   (Canada)

^d UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^e UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Astrogliosis; Cell culture; Epilepsy; Growth factors; Pathology

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CELL ADHESION MOLECULE; GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN SUBUNIT; SODIUM CHANNEL; ENZYME INHIBITOR; GLIAL FIBRILLARY ACIDIC PROTEIN; GROWTH PROMOTOR; HLA DR ANTIGEN; ORGANIC COMPOUND; PD 98058; PEPTIDE FRAGMENT; VIMENTIN;

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; ASTROCYTE; ASTROCYTOSIS; BRAIN INFARCTION; BRAIN TISSUE; CELL FUNCTION; CELL STRUCTURE; CONTROLLED STUDY; CORTICAL DYSPLASIA; ENVIRONMENT; ENZYME INHIBITION; GENE OVEREXPRESSION; GLIOSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOREACTIVITY; IN VITRO STUDY; IN VIVO STUDY; MACROGLIA; MENINGOENCEPHALITIS; MODULATION; MULTIPLE SCLEROSIS; NERVE CELL CULTURE; NERVE CELL PLASTICITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; TEMPORAL LOBE EPILEPSY; UPREGULATION; AMINO ACID SEQUENCE; CASE CONTROL STUDY; CELL CULTURE; CHEMISTRY; COMPARATIVE STUDY; DRUG EFFECT; EPILEPSY; EXTRACELLULAR SPACE; IMMUNOHISTOCHEMISTRY; METABOLISM; PATHOLOGY; SPINAL CORD; TEMPORAL LOBE; TISSUE DISTRIBUTION; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ASTROCYTES; BLOTTING, WESTERN; CASE-CONTROL STUDIES; CELLS, CULTURED; ENZYME INHIBITORS; EPILEPSY; EXTRACELLULAR SPACE; GLIAL FIBRILLARY ACIDIC PROTEIN; GLIOSIS; GROWTH SUBSTANCES; HLA-DR ANTIGENS; HUMANS; IMMUNOHISTOCHEMISTRY; ORGANIC CHEMICALS; PEPTIDE FRAGMENTS; PROTEIN SUBUNITS; SODIUM CHANNELS; SPINAL CORD; TEMPORAL LOBE; TISSUE DISTRIBUTION; VIMENTIN;

EID: 0037712823     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00401-003-0677-2     Document Type: Article

References (55)

1. Aronica E, Vliet EA van, Mayboroda OA, Troost D, Silva FH da, Gorter JA (2000) Upregulation of metabotropic glutamate receptor subtype mGluR3 and mGluR5 in reactive astrocytes in a rat model of mesial temporal lobe epilepsy. Eur J Neurosci 12:2333-2344
2. Aronica E, Catania MV, Geurts J, Yankaya B, Troost D (2001) Immunohistochemical localization of group I and II metabotropic glutamate receptors in control and amyotrophic lateral sclerosis human spinal cord: upregulation in reactive astrocytes. Neuroscience 105:509-520
3. Aronica E, Yankaya B, Jansen GH, Leenstra S, Veelen CW van, Gorter JA, Troost D (2001) Ionotropic and metabotropic glutamate receptor protein expression in glioneuronal tumours from patients with intractable epilepsy. Neuropathol Appl Neurobiol 27:223-237
4. Barres BA, Chun LL, Corey DP (1989) Glial and neuronal forms of the voltage-dependent sodium channel: characteristics and cell-type distribution. Neuron 2:1375-1388
5. Bevan S, Chiu SY, Gray PT, Ritchie JM (1985) The presence of voltage-gated sodium, potassium and chloride channels in rat cultured astrocytes. Proc R Soc Lond B Biol Sci 225:299-313
6. Bevan S, Lindsay RM, Perkins MN, Raff MC (1987) Voltage gated ionic channels in rat cultured astrocytes, reactive astrocytes and an astrocyte-oligodendrocyte progenitor cell. J Physiol 82:327-335
7. Black JA, Waxman SG (1996) Sodium channel expression: a dynamic process in neurons and non-neuronal cells. Dev Neurosci 18:139-152
8. Bordey A, Sontheimer H (1997) Postnatal development of ionic currents in rat hippocampal astrocytes in situ. J Neurophysiol 78:461-477
9. Bordey A, Sontheimer H (1998) Electrophysiological properties of human astrocytic tumor cells In situ: enigma of spiking glial cells. J Neurophysiol 79:2782-2793
10. Bordey A, Sontheimer H (1998) Properties of human glial cells associated with epileptic seizure foci. Epilepsy Res 32:286-303
11. Catterall WA (1995) Structure and function of voltage-gated ion channels. Annu Rev Biochem 64:493-531
12. Catterall WA (1999) Molecular properties of brain sodium channels: an important target for anticonvulsant drugs. Adv Neurol 79:441-456
13. Clarke WE, Berry M, Smith C, Kent A, Logan A (2001) Coordination of fibroblast growth factor receptor 1 (FGFR1) and fibroblast growth factor-2 (FGF-2) trafficking to nuclei of reactive astrocytes around cerebral lesions in adult rats. Mol Cell Neurosci 17:17-30
14. De Groot CJ, Langeveld CH, Jongenelen CA, Montagne L, Van Der Valk P, Dijkstra CD (1997) Establishment of human adult astrocyte cultures derived from postmortem multiple sclerosis and control brain and spinal cord regions: immunophenotypical and functional characterization. J Neurosci Res 49:342-354
15. D'Onofrio M, Cuomo L, Battaglia G, Ngomba RT, Storto M, Kingston AE, Orzi F, De Blasi A, Di Iorio P, Nicoletti F, Bruno V (2001) Neuroprotection mediated by glial group-II metabotropic glutamate receptors requires the activation of the MAP kinase and the phosphatidylinositol-3-kinase pathways. J Neurochem 78:435-445
16. Dudley DT, Pang L, Decker SJ, Bridges AJ, Saltiel AR (1995) A synthetic inhibitor of the mitogen-activated protein kinase cascade. Proc Natl Acad Sci USA 92:7686-7689
17. Ferrer I, Alcantara S, Ballabriga J, Olive M, Blanco R, Rivera R, Carmona M, Berruezo M, Pitarch S, Planas AM (1996) Transforming growth factor-alpha (TGF-alpha) and epidermal growth factor-receptor (EGF-R) immunoreactivity in normal and pathologic brain. Prog Neurobiol 49:99-123
18. Gorter JA, Vliet EA van, Lopes da Silva FH, Isom L, Aronica E (2002) Sodium channel β1-subunit expression is increased in reactive astrocytes in a rat model for mesial temporal lobe epilepsy. Eur J Neurosci 16:360-364
19. Gotoh Y, Nishida E (1995) Activation mechanism and function of the MAP kinase cascade. Mol Reprod Dev 42:486-492
20. Hinterkeuser S, Schroder W, Hager G, Seifert G, Blumcke I, Elger CE, Schramm J, Steinhauser C (2000) Astrocytes in the hippocampus of patients with temporal lobe epilepsy display changes in potassium conductances. Eur J Neurosci 12:2087-2096
21. Isom LL (2001) Sodium channel beta subunits: anything but auxiliary. Neuroscientist 7:42-54
22. Isom LL, De Jongh KS, Patton DE, Reber BF, Offord J, Charbonneau H, Walsh K, Goldin AL, Catterall WA (1992) Primary structure and functional expression of the beta 1 subunit of the rat brain sodium channel. Science 256:839-842
23. Isom LL, Ragsdale DS, De Jongh KS, Westenbroek RE, Reber BF, Scheuer T, Catterall WA (1995) Structure and function of the beta 2 subunit of brain sodium channels, a transmembrane glycoprotein with a CAM motif. Cell 83:433-442
24. Isom LL, Scheuer T, Brownstein AB, Ragsdale DS, Murphy BJ, Catterall WA (1995) Functional co-expression of the beta 1 and type IIA alpha subunits of sodium channels in a mammalian cell line. J Biol Chem 270:3306-3312
25. Khurgel M, Ivy GO (1996) Astrocytes in kindling: relevance to epileptogenesis. Epilepsy Res 26:163-175
26. Labrakakis C, Patt S, Weydt P, Cervos-Navarro J, Meyer R, Kettenmann H (1997) Action potential-generating cells in human glioblastomas. J Neuropathol Exp Neurol 56:243-254
27. Lee SJ, Drabik K, Van Wagoner NJ, Lee S, Choi C, Dong Y, Benveniste EN (2000) ICAM-1-induced expression of proinflammatory cytokines in astrocytes: involvement of extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways. J Immunol 165:4658-4666
28. Malhotra JD, Kazen-Gillespie K, Hortsch M, Isom LL (2000) Sodium channel beta subunits mediate homophilic cell adhesion and recruit ankyrin to points of cell-cell contact. J Biol Chem 275:11383-11388
29. + channel function in the extracellular, domain of the beta 1 subunit. J Biol Chem 273:3954-3962
30. Miller S, Romano C, Cotman CW (1995) Growth factor upregulation of a phosphoinositide-coupled metabotropic glutamate receptor in cortical astrocytes. J Neurosci 15:6103-6109
31. Morgan K, Stevens EB, Shah B, Cox PJ, Dixon AK, Lee K, Pinnock RD, Hughes J, Richardson PJ, Mizuguchi K, Jackson AP (2000) Beta 3: an additional auxiliary subunit of the voltage-sensitive sodium channel that modulates channel gating with distinct kinetics. Proc Natl Acad Sci USA 97:2308-2313
32. + channel is expressed in glial cells. Proc Natl Acad Sci USA 91:9985-9989
33. + channel beta 1 subunit mRNA expression in stellate and flat astrocytes cultured from rat cortex and cerebellum: a combined in situ hybridization and immunocytochemistry study. Glia 13:166-173
34. + channel mRNAs in astrocytes. Brain Res Mol Brain Res 23:57-65
35. + channel beta 1 and beta 2 subunit mRNA levels in cultured rat astrocytes. Neurosci Lett 234:107-110
36. Ojeda SR, Dissen GA, Junier MP (1992) Neurotrophic factors and female sexual development. Front Neuroendocrinol 13: 120-162
37. Opanashuk LA, Mark RJ, Porter J, Damm D, Mattson MP, Seroogy KB (1999) Heparin-binding epidermal growth factor-like growth factor in hippocampus: modulation of expression by seizures and anti-excitotoxic action. J Neurosci 19:133-146
38. Patt S, Labrakakis C, Bernstein M, Weydt P, Cervos-Navarro J, Nisch G, Kettenmann H (1996) Neuron-like physiological properties of cells from human oligodendroglial tumors. Neuroscience 71:601-611
39. Patton DE, Isom LL, Catterall WA, Goldin AL (1994) The adult rat brain beta 1 subunit modifies activation and inactivation gating of multiple sodium channel alpha subunits. J Biol Chem 269:17649-17655
40. Planas AM, Justicia C, Soriano MA, Ferrer I (1998) Epidermal growth factor receptor in proliferating reactive glia following transient focal ischemia in the rat brain. Glia 23:120-129
41. Pollenz RS, McCarthy KD (1986) Analysis of cyclic AMP-dependent changes in intermediate filament protein phosphorylation and cell morphology in cultured astroglia. J Neurochem 47:9-17
42. Rajan P, McKay RD (1998) Multiple routes to astrocytic differentiation in the CNS. J Neurosci 18:3620-3629
43. Rosenberger J, Petrovics G, Buzas B (2001) Oxidative stress induces proorphanin FQ and proenkephalin gene expression in astrocytes through p38- and ERK-MAP kinases and NF-kappaB. J Neurochem 79:35-44
44. + channel beta 1 subunit mRNA expression in developing rat central nervous system. Brain Res Mol Brain Res 34:239-250
45. Shah BS, Stevens EB, Pinnock RD, Dixon AK, Lee K (2001) Developmental expression of the novel voltage-gated sodium channel auxiliary subunit beta3, in rat CNS. J Physiol 534:763-776
46. Smith PK, Krohn RI, Hermanson GT, Mallia AK, Gartner FH, Provenzano MD, Fujimoto EK, Goeke NM, Olson BJ, Klenk DC (1985) Measurement of protein using bicinchoninic acid. Anal Biochem 150:76-85
47. + current types. J Neurophysiol 68:1001-1011
48. Stachowiak MK, Moffett J, Maher P, Tucholski J, Stachowiak EK (1997) Growth factor regulation of cell growth and proliferation in the nervous system. A new intracrine nuclear mechanism. Mol Neurobiol 15:257-283
49. Vandeputte DA, Troost D, Leenstra S, Ijlst-Keizers H, Ramkema M, Bosch DA, Baas F, Das NK, Aronica E (2002) Expression and distribution of id helix-loop-helix proteins in human astrocytic tumors. Glia 38:329-338
50. Verkhratsky A, Steinhauser C (2000) Ion channels in glial cells. Brain Res Brain Res Rev 32:380-412
51. Wandosell F, Bovolenta P, Nieto-Sampedro M (1993) Differences between reactive astrocytes and cultured astrocytes treated with di-butyryl-cyclic AMP. J Neuropathol Exp Neurol 52:205-215
52. Whitaker WR, Clare JJ, Powell AJ, Chen YH, Faull RL, Emson PC (2000) Distribution of voltage-gated sodium channel alpha-subunit and beta-subunit mRNAs in human hippocampal formation, cortex, and cerebellum. J Comp Neurol 422:123-139
53. Xiao ZC, Ragsdale DS, Malhotra JD, Mattei LN, Braun PE, Schachner M, Isom LL (1999) Tenascin-R is a functional modulator of sodium channel beta subunits. J Biol Chem 274: 26511-26517
54. Yamada M, Ikeuchi T, Hatanaka H (1997) The neurotrophic action and signalling of epidermal growth factor. Prog Neurobiol 51:19-37
55. Zhang L, Zhao W, Li B, Alkon DL, Barker JL, Chang YH, Wu M, Rubinow DR (2000) TNF-alpha induced over-expression of GFAP is associated with MAPKs. Neuroreport 11:409-412