An immobilized metal ion affinity adsorption and scintillation proximity assay for receptor-stimulated phosphoinositide hydrolysis

Analytical Biochemistry

Volumn 318, Issue 1, 2003, Pages 91-99

  Liu, Jay Jie ^a   Hartman, Deborah S ^a   Bostwick, James Robert ^a  

^a ASTRAZENECA   (United Kingdom)

Author keywords

Iminodiacetic acid; IP3; Membrane receptor; Phosphatidylinositol; Phospholipase C; Signal transduction

Indexed keywords

AFFINITY CHROMATOGRAPHY; ALCOHOLS; AMINO ACIDS; CHELATION; HYDROLYSIS; ION CHROMATOGRAPHY; METAL IONS; PHOSPHATES; POLYOLS; SCINTILLATION; SIGNAL TRANSDUCTION; SUGARS;

HIGH THROUGHPUT SCREENING; IMINODIACETIC ACID; IMMOBILIZED METAL ION AFFINITY CHROMATOGRAPHIES; MEMBRANE RECEPTORS; PHOSPHATIDYLINOSITOL; PHOSPHOLIPASE C; PLATELET-DERIVED GROWTH FACTORS; SENSITIVE MEASUREMENT;

METALS;

ALUMINUM; G PROTEIN COUPLED RECEPTOR; GALLIUM; INOSITOL; INOSITOL PHOSPHATE; IRON; LUTETIUM; METAL ION; NEUROKININ 1 RECEPTOR; PHOSPHATIDYLINOSITIDE; PLATELET DERIVED GROWTH FACTOR RECEPTOR; SCANDIUM; SUBSTANCE P; TYROSINE KINASE RECEPTOR; ZIRCONIUM;

ANALYTIC METHOD; ANIMAL CELL; ARTICLE; CELL STRAIN 3T3; CHELATION; CHO CELL; CONTROLLED STUDY; FEMALE; HYDROLYSIS; IMMOBILIZED METAL AFFINITY CHROMATOGRAPHY; LIGAND BINDING; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIOACTIVITY; SCINTILLATION PROXIMITY ASSAY; SIGNAL TRANSDUCTION;

EID: 0037686457     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-2697(03)00159-3     Document Type: Article

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