Constraints for zinc finger linker design as inferred from x-ray crystal structure of tandem Zif268-DNA complexes

Journal of Molecular Biology

Volumn 330, Issue 1, 2003, Pages 1-7

  Peisach, Ezra ^a,b   Pabo, Carl O ^a,c  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b Boston University Medical Campus   (United States)

^c SANGAMO BIOSCIENCES INC   (United States)

Author keywords

Linker design; Protein design; Protein DNA; Zif268; Zinc finger

Indexed keywords

DOUBLE STRANDED DNA; PROTEIN; PROTEIN ZIF268; UNCLASSIFIED DRUG; DNA; DNA BINDING PROTEIN; HETERODUPLEX; RECOMBINANT PROTEIN; TRANSCRIPTION FACTOR; ZINC FINGER PROTEIN;

ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; DNA BINDING MOTIF; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STRUCTURE; TANDEM REPEAT; X RAY CRYSTALLOGRAPHY; ZINC FINGER MOTIF; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; MACROMOLECULE; METABOLISM; MOLECULAR GENETICS; PROTEIN CONFORMATION;

AMINO ACID SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DNA; DNA-BINDING PROTEINS; MACROMOLECULAR SUBSTANCES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEIC ACID HETERODUPLEXES; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; TRANSCRIPTION FACTORS; ZINC FINGERS;

EID: 0037666988     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2836(03)00572-2     Document Type: Article

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