Energetics of the specific binding interaction of the first three zinc fingers of the transcription factor TFIIIA with its cognate DNA sequence

Proteins: Structure, Function and Genetics

Volumn 41, Issue SUPPL. 4, 2000, Pages 50-62

  Luque, Irene ^a   Freire, Ernesto ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Calorimetry; Dehydration; Enthalpically driven; Isothermal titration calorimetry; Major groove; Negative heat capacity; Protein DNA association

Indexed keywords

CHICKEN OVALBUMIN UPSTREAM PROMOTER TRANSCRIPTION FACTOR; ZINC FINGER PROTEIN; DNA BINDING PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR IIIA;

ARTICLE; BINDING AFFINITY; CHEMICAL REACTION; DIFFERENTIAL SCANNING CALORIMETRY; DNA SEQUENCE; ENERGY TRANSFER; ENTHALPY; ENTROPY; FLUORESCENCE; HYDRATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DNA INTERACTION; PROTEIN PROTEIN INTERACTION; REACTION ANALYSIS; TEMPERATURE; THERMODYNAMICS; TITRIMETRY; XENOPUS LAEVIS; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM;

CALORIMETRY, DIFFERENTIAL SCANNING; DNA-BINDING PROTEINS; MODELS, MOLECULAR; PROTEIN BINDING; THERMODYNAMICS; TRANSCRIPTION FACTOR TFIIIA; TRANSCRIPTION FACTORS; ZINC FINGERS;

EID: 0033656801     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0134(2000)41:4+<50::AID-PROT50>3.0.CO;2-H     Document Type: Article

References (35)

1. Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes
2. The human genome contains hundreds of genes coding for finger proteins of the Kruppel type
3. A cluster of related zinc finger protein genes is deleted in the mouse embryonic lethal mutation tw18
4. Zinc fingers
5. Zinc finger-DNA recognition: Crystal structure of a Zif268-DNA complex at 2.1 Å
6. Crystal structure of a five-finger GLI-DNA complex: New perspectives on zinc fingers
7. The crystal structure of a two zinc-finger peptide reveals an extension to the rules for zinc-finger/DNA recognition
8. Zif268 protein-DNA complex refined at 1.6 Å: A model system for understanding zinc-finger DNA interactions
9. A 2.2 Å resolution crystal structure of a designed zinc finger protein bound to DNA
10. Solution structure of the first three zinc fingers of TFIIIA bound to the cognate DNA sequence: Determinants of affinity and sequence specificity
11. Domain packing and dynamics in the DNA complex of the N-terminal zinc fingers of TFIIIA
12. Physical basis of a protein-DNA recognition code
13. Coupling of local folding to site-specific binding of proteins to DNA
14. Energetics of folding and DNA binding of the MATα2 homeodomain
15. The energetics of HMG box interactions with DNA. Thermodynamics of the DNA binding to the HMG box from mouse Sox-5
16. Definition of the binding sites of individual zinc fingers in the TFIIIA-5 S RNA gene complex
17. TFIIIA: Nine fingers - Three hands?
18. Specific interaction of the first three zinc fingers of TFIIIA with the internal control region of the Xenopus 5 S RNA gene
19. Assessment of major and minor groove DNA interactions by the zinc fingers of Xenopus transcription factor IIIA
20. Long-range motional restrictions in a multidomain zinc-finger protein from anisotropic tumbling
21. 2 zinc fingers
22. Calculation of protein extinction coefficients from amino acid sequence data
23. Precise scanning calorimeter for studying thermal properties of biological macromolecules in dilute solution
24. The energetics of HMG box interactions with DNA. Thermodynamic description of the box from mouse Sox-5
25. Energetics of protein structure
26. The energetics of HMG box interactions with DNA. Thermodynamic description of the target DNA duplexes
27. The contribution of vibrational entropy to molecular association. The dimerization of insulin
28. Prediction of binding energetics from structure using empirical parameterization
29. Contribution of hydration to protein folding thermodynamics. I. The enthalpy of hydration
30. Buried surface area, conformational entropy, and protein stability
31. The price of lost freedom; the entropy of bimolecular complex formation
32. The entropy cost of protein association
33. On the entropy of protein folding
34. Dynamic contributions to the DNA binding entropy of the EcoRI and EcoRV restriction endonucleases