Synergism between nuclear receptors bound to specific hormone response elements of the hepatic control region-1 and the proximal apolipoprotein C-II promoter mediate apolipoprotein C-II gene regulation by bile acids and retinoids

Biochemical Journal

Volumn 372, Issue 2, 2003, Pages 291-304

  Kardassis, Dimitris ^a,b   Roussou, Anastasia ^a   Papakosta, Paraskevi ^a   Boulias, Konstantinos ^b   Talianidis, Iannis ^b   Zannis, Vassilis I ^a,b  

^a UNIVERSITY OF CRETE   (Greece)

^b INSTITUTE OF MOLECULAR BIOLOGY AND BIOTECHNOLOGY   (Greece)

Author keywords

Apolipoprotein C II (apoC II); Bile acids; Gene regulation; Hepatic control region 1 (HCR 1); Hypertriglyceridaemia

Indexed keywords

CARBOXYLIC ACIDS; DIMERS; GENES; HORMONES; MUTAGENESIS; RNA;

SYNERGISM;

PROTEINS;

ALITRETINOIN; APOLIPOPROTEIN C2; BILE ACID; CELL NUCLEUS RECEPTOR; CHENODEOXYCHOLIC ACID; FARNESOID X RECEPTOR ALPHA; LIOTHYRONINE; MESSENGER RNA; NUCLEAR FACTOR; NUCLEAR FACTOR 4; RECEPTOR; RETINOID DERIVATIVE; RETINOID X RECEPTOR; RETINOID X RECEPTOR ALPHA; THYROID HORMONE RECEPTOR; THYROID HORMONE RECEPTOR BETA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL STRAIN HEPG2; CONTROLLED STUDY; GENE CLUSTER; GENE CONTROL; GENE MUTATION; HORMONE RESPONSIVE ELEMENT; HUMAN; HUMAN CELL; LIVER; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RECEPTOR BINDING; TRANSACTIVATION; TRANSCRIPTION INITIATION;

ANIMALS; ANTINEOPLASTIC AGENTS; APOLIPOPROTEIN C-II; APOLIPOPROTEINS C; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; BLOTTING, WESTERN; CERCOPITHECUS AETHIOPS; CHENODEOXYCHOLIC ACID; CHLORAMPHENICOL O-ACETYLTRANSFERASE; COS CELLS; DIMERIZATION; DNA PRIMERS; DNA-BINDING PROTEINS; DRUG SYNERGISM; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GASTROINTESTINAL AGENTS; GENE EXPRESSION REGULATION; HEPATOCYTE NUCLEAR FACTOR 4; HUMANS; LIVER NEOPLASMS; LUCIFERASES; PHOSPHOPROTEINS; PLASMIDS; PROMOTER REGIONS (GENETICS); RECEPTORS, RETINOIC ACID; RECEPTORS, THYROID HORMONE; REGULATORY SEQUENCES, NUCLEIC ACID; RETINOID X RECEPTORS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEQUENCE DELETION; THYROID HORMONE RECEPTORS BETA; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TRETINOIN;

ANIMALIA;

EID: 0037662830     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20021532     Document Type: Article

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