CP248, a derivative of exisulind, causes growth inhibition, mitotic arrest, and abnormalities in microtubule polymerization in glioma cells

Molecular Cancer Therapeutics

Volumn 1, Issue 6, 2002, Pages 393-404

  Yoon, Jung Taek ^a   Palazzo, Alexander F ^a   Xiao, Danhua ^a   Delohery, Thomas M ^b   Warburton, Peter E ^c   Bruce, Jeffrey N ^a   Thompson, W Joseph ^d   Sperl, Gerhard ^d   Whitehead, Clark ^d   Fetter, John ^d   Pamukcu, Rifat ^d   Gundersen, Gregg G ^a   Weinstein, I Bernard ^a  

^a Columbia University ^*  (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^d Cell Pathways Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3',5' CYCLIC NUCLEOTIDE PHOSPHODIESTERASE; ANTINEOPLASTIC AGENT; CELL CYCLE PROTEIN; CGMP BINDING, CGMP SPECIFIC 3',5' CYCLIC NUCLEOTIDE PHOSPHODIESTERASE; CGMP-BINDING, CGMP-SPECIFIC 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE; CP 461; CYCLIC GMP; CYCLIC GMP DEPENDENT PROTEIN KINASE; CYCLIC GMP PHOSPHODIESTERASE; DRUG DERIVATIVE; MPHOSPH1 PROTEIN, HUMAN; PHOSPHODIESTERASE; PHOSPHODIESTERASE 2A; PHOSPHOPROTEIN; SULINDAC; SULINDAC SULFONE; THYMIDINE;

ANIMAL; APOPTOSIS; ARTICLE; BRAIN TUMOR; CELL DIVISION; CELL STRAIN 3T3; DRUG EFFECT; ENZYME IMMUNOASSAY; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GLIOMA; HUMAN; IN VITRO STUDY; INTERPHASE; METABOLISM; MICROTUBULE; MITOSIS SPINDLE; MOUSE; PATHOLOGY; RAT;

3',5'-CYCLIC-GMP PHOSPHODIESTERASE; 3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; 3T3 CELLS; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BRAIN NEOPLASMS; CELL CYCLE PROTEINS; CELL DIVISION; CYCLIC GMP; CYCLIC GMP-DEPENDENT PROTEIN KINASES; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GLIOMA; HUMANS; IMMUNOENZYME TECHNIQUES; INTERPHASE; MICE; MICROTUBULES; MITOTIC SPINDLE APPARATUS; PHOSPHOPROTEINS; PHOSPHORIC DIESTER HYDROLASES; RATS; SULINDAC; THYMIDINE;

EID: 0037577193     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: None     Document Type: Article

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