Ets transcription factors ER81 and Elk1 regulate the transcription of the human presenilin 1 gene promoter

Molecular Brain Research

Volumn 113, Issue 1-2, 2003, Pages 57-66

  Pastorcic, Martine ^a   Das, Hriday K ^a  

^a UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER   (United States)

Author keywords

Elk 1; ER81; Ets factor; Presenilin; Transcription

Indexed keywords

CHLORAMPHENICOL ACETYLTRANSFERASE; PRESENILIN 1; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ELK 1; TRANSCRIPTION FACTOR ER81; TRANSCRIPTION FACTOR ETS 1; TRANSCRIPTION FACTOR ETS 2; TRANSCRIPTION FACTOR GABP ALPHA; TRANSCRIPTION FACTOR GABP BETA; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DNA LIBRARY; GENETIC SCREENING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; NEUROBLASTOMA CELL; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; TRANSCRIPTION REGULATION; YEAST;

CERVUS ELAPHUS; TRIXIS;

EID: 0037568275     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(03)00090-1     Document Type: Article

References (45)

1. Arber S., Ladle D.R., Lin J.H., Frank E., Jessell T.M., Arber S., Ladle D.R., Lin J.H., Frank E., Jessell T.M. ETS gene Er81 controls the formation of functional connections between group Ia sensory afferents and motor neurons. Cell. 101:2000;485-498.
2. Baert J.L., Beaudoin C., Coutte L., de Launoit Y. ERM transactivation is up-regulated by the repression of DNA binding after the PKA phosphorylation of a consensus site at the edge of the ETS domain. J. Biol. Chem. 277:2002;1002-1012.
3. Brown L.A., Amores A., Schilling T.F., Jowett T., Baert J.-L., Ingham P.W., de Launoit Y., Sharrocks A.D. Molecular characterization of the zebrafish PEA3 ETS-domain transcription factor. Oncogene. 17:1998;93-104.
4. Brown M.S., Ye J., Rawson R.B., Goldstein J.L. Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans. Cell. 100:2000;391-398.
5. Brown T.A., McKnight S.L. Specificities of protein-protein and protein-DNA interaction of GABP alpha and two newly defined ets-related proteins. Genes Dev. 6:1992;2502-2512.
6. Chang L., Thompson M.A. Activity of the distal positive element of the peripherin gene is dependent on proteins binding to an Ets-like recognition site and a novel inverted repeat site. J. Biol. Chem. 271:1996;6467-6475.
7. Chawla S., Hardingham G.E., Quinn D.R., Bading H. CBP: a signal-regulated transcriptional coactivator controlled by nuclear calcium and CaM kinase IV. Science. 281:1998;1505-1509.
8. Chen F., Yu G., Arawaka S., Nishimura M., Kawarai T., Yu H., Tandon A., Supala A., Song Y.-Q., Rogaeva E., Milman P., Sato C., Ahang L., Fraser P.E., St George-Hyslop P. Nicastrin binds to membrane-tethered Notch. Nat. Cell Biol. 3:2001;751-754.
9. Chinenov Y., Henzl M., Martin M.E. The alpha and beta subunits of the GA-binding protein form a stable heterodimer in solution. Revised model of heterotetrameric complex assembly. J. Biol. Chem. 275:2000;7749-7756.
10. Chotteau-Lelievre A., Desbiens X., Pelczar H., Defossez P.A., de Launoit Y. Differential expression patterns of the PEA3 group transcription factors through murine embryonic development. Oncogene. 15:1997;937-952.
11. Chotteau-Lelievre A., Dolle P., Peronne V., Coutte L., de Launoit Y., Desbiens X. Expression patterns of the Ets transcription factors from the PEA3 group during early stages of mouse development. Mech. Dev. 108:2001;191-195.
12. Coutte L., Monté D., Imai K., Pouilly L., Dewitte F., Vidaud M., Adamski J., Baert J.-L., de Launoit Y. Characterization of the human and mouse ETV1/ER81 transcription factor genes: role of the two alternatively spliced isoforms in the human. Oncogene. 18:1999;6278-6286.
13. Garvie C.W., Pufall M.A., Graves B.J., Wolberger C. Structural analysis of the autoinhibition of Ets-1 and its role in protein partnerships. J. Biol. Chem. 277:2002;45529-45536.
14. Graves B.J., Petersen J. Specificity within the ets family of transcription factors. Adv. Cancer Res. 75:1998;1-5.
15. Janknecht R. Analysis of the ERK-stimulated ETS transcription factor ER81. Mol. Cell. Biol. 16:1996;1550-1556.
16. Janknecht R., Monté D., Baert J.-L., de Launoit Y. The ETS-related transcription factor ERM is a nuclear target of signaling cascades involving MAPK and PKA. Oncogene. 13:1996;1745-1754.
17. Jeon I.S., Davis J.N., Braun B.S., Sublett J.E., Roussel M.F., Denny C.T., Shapiro D.N. A variant Ewing's sarcoma translocation (7;22) fuses the EWS gene to the ETS gene ETV1. Oncogene. 10:1995;1229-1234.
18. Laudet V., Hanni C., Stehelin D., Duterque-Coquillaud M. Molecular phylogeny of the ETS gene family. Oncogene. 18:1999;1351-1359.
19. Leem J.Y., Vijayan S., Han P., Cai D., Machura M., Lopes K.O., Veselits M.L., Xu H., Thinakaran G. Presenilin 1 is required for maturation and cell surface accumulation of nicastrin. J. Biol. Chem. 277:2002;19236-19240.
20. Li X., Greenwald I. Membrane topology of the C. elegans SEL-12 presenilin. Neuron. 17:1996;1015-1021.
21. Li X., Greenwald I. Additional evidence for an eight-transmembrane-domain topology for Caenorhabditis elegans and human presenilins. Proc. Natl. Acad. Sci. USA. 95:1998;7109-7114.
22. Li Y.-M., Lai M.-T., Xu M., Huang Q., DiMuzio-Mower J., Sardana M.K., Shi X.-P., Yin K.-C., Shafer J.A., Gardell S.J. Presenilin 1 is linked with gamma-secretase activity in the detergent solubilized state. Proc. Natl. Acad. Sci. USA. 97:2000;6138-6143.
23. McDonough J., Francis N., Miller T., Deneris E.S. Regulation of transcription in the neuronal nicotinic receptor subunit gene cluster by a neuron-selective enhancer and ETS domain factors. J. Biol. Chem. 75:2000;28962-28970.
24. Monte D., Coutte L., Baert J.L., Angeli I., Stehelin D., de Launoit Y. Molecular characterization of the Ets-related human transcription factor ER81. Oncogene. 11:1995;771-779.
25. Neves S.R., Ram P.T., Iyengar R. G protein pathways. Science. 296:2002;1636-1639.
26. O'Hagan R.C., Tozer R.G., Symons M., McCormick F., Hassell J.A. The activity of the Ets transcription factor PEA3 is regulated by two distinct MAPK cascades. Oncogene. 13:1996;1323-1333.
27. Pastorcic M., Das H.K. An upstream element containing an ETS binding site is crucial for transcription of the human presenilin-1 gene. J. Biol. Chem. 274:1999;24297-24307.
28. Pastorcic M., Das H.K. Regulation of transcription of the human presenilin-1 gene by Ets transcription factors and the p53 protooncogene. J. Biol. Chem. 275:2000;34938-34945.
29. Petersohn D., Schoch S., Brinkmann D.R., Thiel G. The human synapsin II gene promoter. Possible role for the transcription factor zif268/egr-1, polyoma enhancer activator 3, and AP2. J. Biol. Chem. 270:1995;24361-24369.
30. Pufall M.A., Graves B.J. Ets-1 flips for new partner Pax-5. Structure (Camb.). 10:2002;11-14.
31. Rao V.N., Huebner K., Isobe M., ar-Rushdi A., Croce C.M., Reddy E.S. elk, tissue-specific Ets-related genes on chromosomes X and 14 near translocation breakpoints. Science. 244:1989;66-70.
32. Rogaev E.I., Sherrington R., Rogaeva E.A., Levesque G., Ikeda M., Liang Y., Chi H., Lin C., Holman K., Tsuda T., Mar L., Sorbi S., Nacmias B., Piacentini S., Chumakov I., Cohen D., Lannfelt L., Fraser P.E., Rommens J.M., St George-Hyslop P.H. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature. 376:1995;775-778.
33. Rosen L.B., Ginty D.D., Weber M.J., Greenberg M.E. Membrane depolarization and calcium influx stimulate MEK and MAP kinase via activation of Ras. Neuron. 12:1994;1207-1221.
34. Schaeffer L., Duclert N., Huchet-Dymanus M., Changeux J.P. Implication of a multisubunit Ets-related transcription factor in synaptic expression of the nicotinic acetylcholine receptor. EMBO J. 17:1998;3078-3090.
35. Schaeffer L., de Kerchove d'Exaerde A., Changeux J.P. Targeting transcription to the neuromuscular synapse. Neuron. 31:2001;15-22.
36. Selkoe D.J. Translating cell biology into therapeutic advances in Alzheimer's disease. Nature. 399:1999;23-31.
37. Shen J., Bronson R.T., Chen D.F., Xia W., Selkoe D.J., Tonegawa S. Skeletal and CNS defects in Presenilin-1-deficient mice. Cell. 89:1997;629-639.
38. Sherrington R., Rogaev E.I., Liang Y., Rogaeva E.A., Levesque G., Ikeda M., Chi H., Lin C., Li G., Holman K., Tsuda T., Mar L., Foncin J.F., Bruni A.C., Montesi M.P., Sorbi S., Rainero L., Pinessi L., Nee L., Chumakov I., Pollen D., Brookes A., Sanseau P., Polinski R.G., Wasco W., da Silva H.A.R., Haines J.L., Pericak-Vance M.A., Tanzi R.E., Roses A.D., Fraser P.E., Rommens J.M., St. George-Hyslop P.H. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature. 375:1995;754-760.
39. Shore P., Bisset L., Lakey J., Waltho J.P., Virden R., Sharrocks A.D. Characterization of the Elk-1 ETS DNA-binding domain. J. Biol. Chem. 270:1995;5805-5811.
40. Taniguchi Y., Karlstrom H., Lundkvist J., Mizutani T., Otaka A., Vestling M., Bernstein A., Donoviel D., Lendahl U., Honjo T. Notch receptor cleavage depends on but is not directly executed by presenilins. Proc. Natl. Acad. Sci. USA. 99:2002;4014-4019.
41. Tanzi R.E., Kowacs D.M., Kim T.-W., Moir R.D., Guenette S.Y., Wasco W. The gene defects responsible for familial Alzheimer's disease. Neurobiol. Dis. 3:1996;159-168.
42. Wong P.C., Zeng H., Chen H., Becher M.W., Sirinathsinghji D.J.S., Trumbauer M.E., Chen H.Y., Price D.L., Van der Ploeg L.H.T., Sisodia S.S. Presenilin 1 is required for Notch1 and DII1 expression in the paraxial mesoderm. Nature. 387:1997;288-292.
43. Wu J., Janknecht R. Regulation of the ETS transcription factor ER81 by the 90-kDa ribosomal S6 kinase 1 and protein kinase A. J. Biol. Chem. 277:2002;42669-42679.
44. Yu G., Nishimura M., Arawaka S., Levitan D., Zhang L., Tandon A., Song Y.-Q., Rogaeva E., Chen F., Kawarai T., Supala A., Levesque L., Yu H., Yang D.-S., Holmes E., Milman P., Liang Y., Zhang D.M., Xu D.H., Sato C., Rogaev E., Smith M., Janus C., Zhang Y., Aebersold R., Farrer L., Sorbi S., Bruni A., Fraser P.E., St George-Hyslop P. Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing. Nature. 407:2000;48-54.
45. Zhou J., Liyanage U., Medina M., Ho C., Simmons A.D., Lovett M., Kosik K.S. Presenilin 1 interaction in the brain with a novel member of the Armadillo family. Neuroreport. 8:1997;2085-2090.