Gene expression of Toll-like receptors and associated molecules induced by inflammatory stimuli in the primary alveolar macrophage

Biochemical and Biophysical Research Communications

Volumn 305, Issue 3, 2003, Pages 649-655

  Oshikawa, Katsuhisa ^a   Sugiyama, Yukihiko ^a  

^a JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

Acute lung injury; Lipopolysaccharide; Proinflammatory cytokine; Toll like receptor

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CD14 ANTIGEN; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MEDIATED LYMPHOLYSIS; CELL STIMULATION; DOWN REGULATION; GENE EXPRESSION; HUMORAL IMMUNITY; IN VITRO STUDY; LUNG ALVEOLUS MACROPHAGE; LUNG INJURY; LUNG PARENCHYMA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY TRACT INFECTION; TISSUE REACTION; UPREGULATION;

BACTERIA (MICROORGANISMS); MURINAE;

EID: 0037564286     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(03)00837-4     Document Type: Article

References (39)

1. Glauser M.P., Zanetti G., Baumgartner J.D., Cohen J. Septic shock: pathogenesis. Lancet. 338:1991;732-736.
2. Rietschel E.T., Brade H. Bacterial endotoxins. Sci. Am. 267:1992;54-61.
3. Hailman E., Lichenstein H.S., Wurfel M.M., Miller D.S., Johnson D.A., Kelley M., Busse L.A., Zukowski M.M., Wright S.D. Lipopolysaccharide (LPS)-binding protein accelerates the binding of LPS to CD14. J. Exp. Med. 179:1994;269-277.
4. Medzhitov R., Janeway C. Innate immunity. N. Engl. J. Med. 343:2000;338-344.
5. Aderem A., Ulevitch R.J. Toll-like receptors in the induction of the innate immune response. Nature. 406:2000;782-787.
6. Rock F.L., Hardiman G., Timans J.C., Kastelein R.A., Bazan J.F. A family of human receptors structurally related to Drosophila Toll. Proc. Natl. Acad. Sci. USA. 95:1998;588-593.
7. Du X., Poltorak A., Wei Y., Beutler B. Three novel mammalian Toll-like receptors: gene structure, expression, and evolution. Eur. Cytokine Netw. 11:2000;362-371.
8. Hirschfeld M., Ma Y., Weis J.H., Vogel S.N., Weis J.J. Cutting edge: repurification of lipopolysaccharide eliminates signaling through both human and murine toll-like receptor 2. J. Immunol. 165:2000;618-622.
9. Takeuchi O., Hoshino K., Kawai T., Sanjo H., Takada H., Ogawa T., Takeda K., Akira S. Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components. Immunity. 11:1999;443-451.
10. Heine H., Kirschning C.J., Lien E., Monks B.G., Rothe M., Golenbock D.T. Cutting edge: cells that carry a null allele for toll-like receptor 2 are capable of responding to endotoxin. J. Immunol. 162:1999;6971-6975.
11. Schwandner R., Dziarski R., Wesche H., Rothe M., Kirschning C.J. Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2. J. Biol.Chem. 274:1999;17406-17409.
12. Lien E., Sellati T.J., Yoshimura A., Flo T.H., Rawadi G., Finberg R.W., Carroll J.D., Espevik T., Ingalls R.R., Radolf J.D., Golenbock D.T. Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products. J. Biol. Chem. 274:1999;33419-33425.
13. Brightbill H.D., Libraty D.H., Krutzik S.R., Yang R.B., Belisle J.T., Bleharski J.R., Maitland M., Norgard M.V., Plevy S.E., Smale S.T., Brennan P.J., Bloom B.R., Godowski P.J., Modlin R.L. Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors. Science. 285:1999;732-736.
14. Yoshimura A., Lien E., Ingalls R.R., Tuomanen E., Dziarski R., Golenbock D. Cutting edge: recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2. J. Immunol. 163:1999;1-5.
15. Poltorak A., He X., Smirnova I., Liu M.Y., Huffel C.V., Du X., Birdwell D., Alejos E., Silva M., Galanos C., Freudenberg M., Ricciardi-Castagnoli P., Layton B., Beutler B. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science. 282:1998;2085-2088.
16. Hoshino K., Takeuchi O., Kawai T., Sanjo H., Ogawa T., Takeda Y., Takeda K., Akira S. Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product. J. Immunol. 162:1999;3749-3752.
17. Takeuchi O., Hoshino K., Akira S. Cutting edge: TLR2-deficient and MyD88-deficient mice are highly susceptible to Staphylococcus aureus infection. J. Immunol. 165:2000;5392-5396.
18. Muzio M., Natoli G., Saccani S., Levrero M., Mantovani A. The human toll signaling pathway: divergence of nuclear factor kappaB and JNK/SAPK activation upstream of tumor necrosis factor receptor-associated factor 6 (TRAF6). J. Exp. Med. 187:1998;2097-2101.
19. Cario E., Rosenberg I.M., Brandwein S.L., Beck P.L., Reinecker H.C., Podolsky D.K. Lipopolysaccharide activates distinct signaling pathways in intestinal epithelial cell lines expressing Toll-like receptors. J. Immunol. 164:2000;966-972.
20. Matsuguchi T., Musikacharoen T., Ogawa T., Yoshikai Y. Gene expressions of Toll-like receptor 2, but not Toll-like receptor 4, is induced by LPS and inflammatory cytokines in mouse macrophages. J. Immunol. 165:2000;5767-5772.
21. Matsuguchi T., Takagi K., Musikacharoen T., Yoshikai Y. Gene expressions of lipopolysaccharide receptors, toll-like receptors 2 and 4, are differently regulated in mouse T lymphocytes. Blood. 95:2000;1378-1385.
22. Faure E., Thomas L., Xu H., Medvedev A., Equils O., Arditi M. Bacterial lipopolysaccharide and IFN-gamma induce Toll-like receptor 2 and Toll-like receptor 4 expression in human endothelial cells: role of NF-kappa B activation. J. Immunol. 166:2001;2018-2024.
23. Muzio M., Bosisio D., Polentarutti N., D'amico G., Stoppacciaro A., Mancinelli R., van't Veer C., Penton-Rol G., Ruco L.P., Allavena P., Mantovani A. Differential expression and regulation of toll-like receptors (TLR) in human leukocytes: selective expression of TLR3 in dendritic cells. J. Immunol. 164:2000;5998-6004.
24. Sabroe I., Jones E.C., Usher L.R., Whyte M.K., Dower S.K. Toll-like receptor (TLR)2 and TLR4 in human peripheral blood granulocytes: a critical role for monocytes in leukocyte lipopolysaccharide responses. J. Immunol. 168:2002;4701-4710.
25. Akira S. Toll-like receptors and innate immunity. Adv. Immunol. 78:2001;1-56.
26. Hudson L.D., Milberg J.A., Anardi D., Maunder R.J. Clinical risks for development of the acute respiratory distress syndrome. Am. J. Resp. Crit. Care Med. 151:1995;293-301.
27. Martin T.R., Mathison J.C., Tobias P.S., Leturcq D.J., Moriarty A.M., Maunder R.J., Ulevitch R.J. Lipopolysaccharide binding protein enhances the responsiveness of alveolar macrophages to bacterial lipopolysaccharide. Implications for cytokine production in normal and injured lungs. J. Clin. Invest. 90:1992;2209-2219.
28. Meduri G.U., Kohler G., Headley S., Tolley E., Stentz F., Postlethwaite A. Inflammatory cytokines in the BAL of patients with ARDS. Persistent elevation over time predicts poor outcome. Chest. 108:1995;1303-1314.
29. Oshikawa K., Yanagisawa K., Tominaga S., Sugiyama Y. ST2 protein induced by inflammatory stimuli can modulate acute lung inflammation. Biochem. Biophys. Res. Commun. 299:2002;18-24.
30. Lin Y.Z., Yao S.Y., Veach R.A., Torgerson T.R., Hawiger J. Inhibition of nuclear translocation of transcription factor NF-kappa B by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence. J. Biol. Chem. 270:1995;14255-14258.
31. Szarka R.J., Wang N., Gordon L., Nation P.N., Smith R.H. A murine model of pulmonary damage induced by lipopolysaccharide via intranasal instillation. J. Immunol. Methods. 202:1997;49-57.
32. Oshikawa K., Yanagisawa K., Ohno S., Tominaga S., Sugiyama Y. Expression of ST2 in helper T lymphocytes of malignant pleural effusions. Am. J. Resp. Crit. Care Med. 165:2002;1005-1009.
33. Medvedev A.E., Kopydlowski K.M., Vogel S.N. Inhibition of lipopolysaccharide-induced signal transduction in endotoxin-tolerized mouse macrophages: dysregulation of cytokine, chemokine, and toll-like receptor 2 and 4 gene expression. J. Immunol. 164:2000;5564-5574.
34. Laskin D.L., Weinberger B., Laskin J.D. Functional heterogeneity in liver and lung macrophages. J. Leukoc. Biol. 70:2001;163-170.
35. Fan J., Ye R.D., Malik A.B. Transcriptional mechanisms of acute lung injury. Am. J. Physiol. Lung Cell. Mol. Physiol. 281:2001;1037-1050.
36. Jiang Q., Akashi S., Miyake K., Petty H.R. Lipopolysaccharide induces physical proximity between CD14 and toll-like receptor 4 (TLR4) prior to nuclear translocation of NF-kappa B. J. Immunol. 165:2000;3541-3544.
37. Nomura F., Akashi S., Sakao Y., Sato S., Kawai T., Matsumoto M., Nakanishi K., Kimoto M., Miyake K., Takeda K., Akira S. Cutting edge: endotoxin tolerance in mouse peritoneal macrophages correlates with down-regulation of surface toll-like receptor 4 expression. J. Immunol. 164:2000;3476-3479.
38. Musikacharoen T., Matsuguchi T., Kikuchi T., Yoshikai Y. NF-kappa B and STAT5 play important roles in the regulation of mouse Toll-like receptor 2 gene expression. J. Immunol. 166:2001;4516-4524.
39. Wang T., Lafuse W.P., Zwilling B.S. NFkappaB and Sp1 elements are necessary for maximal transcription of toll-like receptor 2 induced by Mycobacterium avium. J. Immunol. 167:2001;6924-6932.