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Volumn 33, Issue 6, 2003, Pages 834-841

Probing the mechanisms of low immunogenicity of a lipocalin allergen, Bos d 2, in a mouse model

Author keywords

Allergenicity; Animal allergen; Immune response; Immunogenicity; Lipocalin; T cell

Indexed keywords

ALLERGEN; AMINO ACID DERIVATIVE; ANTIGEN; CANCER GROWTH FACTOR; CARBOXYFLUORESCEIN DIACETATE SUCCINIMIDYL ESTER; CYTOKINE; DYE; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 2; INTERLEUKIN 4; LIPOCALIN; LYSOZYME; TETANUS TOXOID;

EID: 0037533027     PISSN: 09547894     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2222.2003.01669.x     Document Type: Article
Times cited : (8)

References (37)
  • 1
    • 0033836431 scopus 로고    scopus 로고
    • Structural biology of allergens
    • Aalberse RC. Structural biology of allergens. J Allergy Clin Immunol 2000; 106:228-38.
    • (2000) J Allergy Clin Immunol , vol.106 , pp. 228-238
    • Aalberse, R.C.1
  • 2
    • 0344327066 scopus 로고    scopus 로고
    • T cell epitopes of a lipocalin allergen colocalize with the conserved regions of the molecule
    • Zeiler T, Mäntyjärvi R, Rautiaine J et al. T cell epitopes of a lipocalin allergen colocalize with the conserved regions of the molecule. J Immunol 1999; 162:1415-22.
    • (1999) J Immunol , vol.162 , pp. 1415-1422
    • Zeiler, T.1    Mäntyjärvi, R.2    Rautiaine, J.3
  • 3
    • 0026528871 scopus 로고
    • IgG and IgE antibody responses to cow dander and urine in farmers with cow-induced asthma
    • Ylönen J, Mäntyjärvi R, Taivainen A, Virtanen T. IgG and IgE antibody responses to cow dander and urine in farmers with cow-induced asthma. Clin Exp Allergy 1992; 22:83-90.
    • (1992) Clin Exp Allergy , vol.22 , pp. 83-90
    • Ylönen, J.1    Mäntyjärvi, R.2    Taivainen, A.3    Virtanen, T.4
  • 4
    • 0036408856 scopus 로고    scopus 로고
    • Threshold levels of purified natural Bos d 2 for inducing bronchial airway response in asthmatic patients
    • Zeiler T, Taivainen A, Mäntyjärvi R et al. Threshold levels of purified natural Bos d 2 for inducing bronchial airway response in asthmatic patients. Clin Exp Allergy 2002; 32:1454-60.
    • (2002) Clin Exp Allergy , vol.32 , pp. 1454-1460
    • Zeiler, T.1    Taivainen, A.2    Mäntyjärvi, R.3
  • 5
    • 0036207314 scopus 로고    scopus 로고
    • Lipocalin allergen Bos d 2 is a weak immunogen
    • Saarelainen S, Zeiler T, Rautiainen J et al. Lipocalin allergen Bos d 2 is a weak immunogen. Int Immunol 2002; 14:401-9.
    • (2002) Int Immunol , vol.14 , pp. 401-409
    • Saarelainen, S.1    Zeiler, T.2    Rautiainen, J.3
  • 6
    • 0033199285 scopus 로고    scopus 로고
    • Allergy to lipocalins: A consequence of misguided T-cell recognition of self and nonself?
    • Virtanen T, Zeiler T, Rautiainen J, Mäntyjärvi R. Allergy to lipocalins: a consequence of misguided T-cell recognition of self and nonself? Immunol Today 1999; 20:398-400.
    • (1999) Immunol Today , vol.20 , pp. 398-400
    • Virtanen, T.1    Zeiler, T.2    Rautiainen, J.3    Mäntyjärvi, R.4
  • 7
    • 0030801002 scopus 로고    scopus 로고
    • Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
    • Altschul SF, Madden TL, Schaffer AA et al. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucl Acids Res 1997; 25:3389-402.
    • (1997) Nucl Acids Res , vol.25 , pp. 3389-3402
    • Altschul, S.F.1    Madden, T.L.2    Schaffer, A.A.3
  • 8
    • 0028032155 scopus 로고
    • Positive selection of lymphocytes
    • von Boehmer H. Positive selection of lymphocytes. Cell 1994; 76:219-28.
    • (1994) Cell , vol.76 , pp. 219-228
    • Von Boehmer, H.1
  • 9
    • 0028151819 scopus 로고
    • Negative selection of lymphocytes
    • Nossal GJV. Negative selection of lymphocytes. Cell 1994; 76:229-39.
    • (1994) Cell , vol.76 , pp. 229-239
    • Nossal, G.J.V.1
  • 12
    • 0031966005 scopus 로고    scopus 로고
    • How the MHC selects Th1/Th2 immunity
    • Murray JS. How the MHC selects Th1/Th2 immunity. Immunol Today 1998; 19:157-63.
    • (1998) Immunol Today , vol.19 , pp. 157-163
    • Murray, J.S.1
  • 14
    • 0032577941 scopus 로고    scopus 로고
    • Molecular and crystal properties of Bos d 2, an allergenic protein of the lipocalin family
    • Rautiainen J, Auriola S, Rouvinen J et al. Molecular and crystal properties of Bos d 2, an allergenic protein of the lipocalin family. Bioch Biophys Res Comm 1998; 247:746-50.
    • (1998) Bioch Biophys Res Comm , vol.247 , pp. 746-750
    • Rautiainen, J.1    Auriola, S.2    Rouvinen, J.3
  • 15
    • 0033593449 scopus 로고    scopus 로고
    • Probing the molecular basis of allergy - Three-dimensional structure of the bovine lipocalin allergen Bos d 2
    • Rouvinen J, Rautiainen J, Virtanen T et al. Probing the molecular basis of allergy - three-dimensional structure of the bovine lipocalin allergen Bos d 2. J Biol Chem 1999; 274:2337-43.
    • (1999) J Biol Chem , vol.274 , pp. 2337-2343
    • Rouvinen, J.1    Rautiainen, J.2    Virtanen, T.3
  • 16
    • 0002230857 scopus 로고    scopus 로고
    • Morphological, biochemical and flow cytometric assays of apoptosis
    • Coico R, ed. Chichester: John Wiley & Sons
    • Martin D, Lenardo M. Morphological, biochemical and flow cytometric assays of apoptosis. In: Coico R, ed. Current Protocols in Immunology. Chichester: John Wiley & Sons, 1998:3.17.1-3.17.39.
    • (1998) Current Protocols in Immunology , pp. 3171-31739
    • Martin, D.1    Lenardo, M.2
  • 17
    • 0032526853 scopus 로고    scopus 로고
    • Endogenous myelin basic protein inactivates the high avidity T cell repertoire
    • Targoni OS, Lehmann PV. Endogenous myelin basic protein inactivates the high avidity T cell repertoire. J Exp Med 1998; 187:2055-63.
    • (1998) J Exp Med , vol.187 , pp. 2055-2063
    • Targoni, O.S.1    Lehmann, P.V.2
  • 18
    • 0028354216 scopus 로고
    • Small splenic B cells that bind to antigen-specific T helper (Th) cells and face the site of cytokine production in the Th cells selectively proliferate: Immunofluorescence microscopic studies of Th-B antigen-presenting cell interactions
    • Kupfer H, Monks CR, Kupfer A. Small splenic B cells that bind to antigen-specific T helper (Th) cells and face the site of cytokine production in the Th cells selectively proliferate: immunofluorescence microscopic studies of Th-B antigen-presenting cell interactions. J Exp Med 1994; 179:1507-15.
    • (1994) J Exp Med , vol.179 , pp. 1507-1515
    • Kupfer, H.1    Monks, C.R.2    Kupfer, A.3
  • 19
    • 0031571809 scopus 로고    scopus 로고
    • Immunodominance is independent of structural constraints - Each region within hen eggwhite lysozyme is potentially available upon processing of native antigen
    • Moudgil KD, Sekiguchi D, Kim SY, Sercarz EE. Immunodominance is independent of structural constraints - each region within hen eggwhite lysozyme is potentially available upon processing of native antigen. J Immunol 1997; 159:2574-9.
    • (1997) J Immunol , vol.159 , pp. 2574-2579
    • Moudgil, K.D.1    Sekiguchi, D.2    Kim, S.Y.3    Sercarz, E.E.4
  • 20
    • 0344915162 scopus 로고    scopus 로고
    • Adjuvant-guided type-1 and type-2 immunity: Infectious/noninfectious dichotomy defines the class of response
    • Yip HC, Karulin AY, Tary-Lehmann M et al. Adjuvant-guided type-1 and type-2 immunity: infectious/noninfectious dichotomy defines the class of response. J Immunol 1999; 162:3942-9.
    • (1999) J Immunol , vol.162 , pp. 3942-3949
    • Yip, H.C.1    Karulin, A.Y.2    Tary-Lehmann, M.3
  • 21
    • 0031975213 scopus 로고    scopus 로고
    • + T cell clones mediate the in vivo inhibition of rat IgE
    • + T cell clones mediate the in vivo inhibition of rat IgE. J Immunol 1998; 160:580-7.
    • (1998) J Immunol , vol.160 , pp. 580-587
    • MacAry, P.A.1    Holmes, B.J.2    Kemeny, D.M.3
  • 22
    • 0030056468 scopus 로고    scopus 로고
    • Models of T cell anergy: Is there a common molecular mechanism?
    • Schwartz RH. Models of T cell anergy: is there a common molecular mechanism? J Exp Med 1996; 184:1-8.
    • (1996) J Exp Med , vol.184 , pp. 1-8
    • Schwartz, R.H.1
  • 23
    • 0033558119 scopus 로고    scopus 로고
    • Dose-dependent induction of distinct anergic phenotypes: Multiple levels of T cell anergy
    • Taams LS, van Eden W, Wauben MHM. Dose-dependent induction of distinct anergic phenotypes: multiple levels of T cell anergy. J Immunol 1999; 162:1974-81.
    • (1999) J Immunol , vol.162 , pp. 1974-1981
    • Taams, L.S.1    Van Eden, W.2    Wauben, M.H.M.3
  • 24
    • 0026687519 scopus 로고
    • Reversal of in vitro T cell clonal anergy by IL-2 stimulation
    • Beverly B, Kang SM, Lenardo MJ, Schwartz RH. Reversal of in vitro T cell clonal anergy by IL-2 stimulation. Int Immunol 1992; 4:661-71.
    • (1992) Int Immunol , vol.4 , pp. 661-671
    • Beverly, B.1    Kang, S.M.2    Lenardo, M.J.3    Schwartz, R.H.4
  • 25
    • 0031821875 scopus 로고    scopus 로고
    • + immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
    • + immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J Exp Med 1998; 188:287-96.
    • (1998) J Exp Med , vol.188 , pp. 287-296
    • Thornton, A.M.1    Shevach, E.M.2
  • 26
    • 0031743403 scopus 로고    scopus 로고
    • Neonatal exposure to a self-peptide-immunoglobulin chimera circumvents the use of adjuvant and confers resistance to autoimmune disease by a novel mechanism involving interleukin 4 lymph node deviation and interferon gamma-mediated splenic anergy
    • Min B, Legge KL, Pack C, Zaghouani H. Neonatal exposure to a self-peptide-immunoglobulin chimera circumvents the use of adjuvant and confers resistance to autoimmune disease by a novel mechanism involving interleukin 4 lymph node deviation and interferon gamma-mediated splenic anergy. J Exp Med 1998; 188:2007-17.
    • (1998) J Exp Med , vol.188 , pp. 2007-2017
    • Min, B.1    Legge, K.L.2    Pack, C.3    Zaghouani, H.4
  • 27
    • 0029847368 scopus 로고    scopus 로고
    • Functional diversity of helper T lymphocytes
    • Abbas AK, Murphy KM, Sher A. Functional diversity of helper T lymphocytes. Nature 1996; 383:787-93.
    • (1996) Nature , vol.383 , pp. 787-793
    • Abbas, A.K.1    Murphy, K.M.2    Sher, A.3
  • 28
    • 0032861775 scopus 로고    scopus 로고
    • What is the role of regulatory T cells in transplantation tolerance?
    • Zhai Y, Kupiec-Weglinski JW. What is the role of regulatory T cells in transplantation tolerance? Curr Opin Immunol 1999; 11:497-503.
    • (1999) Curr Opin Immunol , vol.11 , pp. 497-503
    • Zhai, Y.1    Kupiec-Weglinski, J.W.2
  • 30
    • 0023501915 scopus 로고
    • Heterogeneity of helper/inducer T lymphocytes. I. Lymphokine production and lymphokine responsiveness
    • Kurt-Jones EA, Hamberg S, Ohara J, Paul WE, Abbas AK. Heterogeneity of helper/inducer T lymphocytes. I. Lymphokine production and lymphokine responsiveness. J Exp Med 1987; 166:1774-87.
    • (1987) J Exp Med , vol.166 , pp. 1774-1787
    • Kurt-Jones, E.A.1    Hamberg, S.2    Ohara, J.3    Paul, W.E.4    Abbas, A.K.5
  • 31
    • 0026316280 scopus 로고
    • Clonal anergy blocks the response to IL-4, as well as the production of IL-2, in dual-producing T helper cell clones
    • Mueller DL, Chiodetti L, Bacon PA, Schwartz RH. Clonal anergy blocks the response to IL-4, as well as the production of IL-2, in dual-producing T helper cell clones. J Immunol 1991; 147:4118-25.
    • (1991) J Immunol , vol.147 , pp. 4118-4125
    • Mueller, D.L.1    Chiodetti, L.2    Bacon, P.A.3    Schwartz, R.H.4
  • 32
    • 0030704726 scopus 로고    scopus 로고
    • + T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
    • + T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature 1997; 389:737-42.
    • (1997) Nature , vol.389 , pp. 737-742
    • Groux, H.1    O'Garra, A.2    Bigler, M.3
  • 34
    • 0034163391 scopus 로고    scopus 로고
    • A conserved mycobacterial heat shock protein (HSP) 70 sequence prevents adjuvant arthritis upon nasal administration and induces IL-10-producing T cells that cross-react with the mammalian self-HSP70 homologue
    • Wendling U, Paul L, van der Zee R, Prakken B, Singh M, van Eden W. A conserved mycobacterial heat shock protein (HSP) 70 sequence prevents adjuvant arthritis upon nasal administration and induces IL-10-producing T cells that cross-react with the mammalian self-HSP70 homologue. J Immunol 2000; 164:2711-7.
    • (2000) J Immunol , vol.164 , pp. 2711-2717
    • Wendling, U.1    Paul, L.2    Van Der Zee, R.3    Prakken, B.4    Singh, M.5    Van Eden, W.6
  • 35
    • 0032921181 scopus 로고    scopus 로고
    • IL-10-induced anergy in peripheral T cell and reactivation by microenvironmental cytokines: Two key steps in specific immunotherapy
    • Akdis CA, Blaser K. IL-10-induced anergy in peripheral T cell and reactivation by microenvironmental cytokines: two key steps in specific immunotherapy. FASEB J 1999; 13:603-9.
    • (1999) FASEB J , vol.13 , pp. 603-609
    • Akdis, C.A.1    Blaser, K.2
  • 37
    • 0032564340 scopus 로고    scopus 로고
    • In vivo antagonism of a T cell response by an endogenously expressed ligand
    • Basu D, Williams CB, Allen PM. In vivo antagonism of a T cell response by an endogenously expressed ligand. Proc Natl Acad Sci USA 1998; 95:14332-6.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 14332-14336
    • Basu, D.1    Williams, C.B.2    Allen, P.M.3


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