Exploring the potential of xanthene derivatives as trypanothione reductase inhibitors and chloroquine potentiating agents

Tetrahedron

Volumn 59, Issue 13, 2003, Pages 2289-2296

  Chibale, Kelly ^a   Visser, Mark ^a   Van Schalkwyk, Donelly ^b   Smith, Peter J ^b   Saravanamuthu, Ahilan ^c   Fairlamb, Alan H ^c  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b UNIVERSITY OF CAPE TOWN   (South Africa)

^c UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

9,9 dimethylxanthenes; Chloroquine potentiating agents; Leishmaniasis; Malaria; Trypanosomiasis; Trypanothione reductase inhibitors

Indexed keywords

CHLOROQUINE; ENZYME INHIBITOR; TRICYCLIC ANTIDEPRESSANT AGENT; TRYPANOTHIONE INHIBITOR; TRYPANOTHIONE REDUCTASE; UNCLASSIFIED DRUG; XANTHENE DERIVATIVE;

ANTIMALARIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG POTENTIATION; DRUG RESISTANCE; ENZYME ACTIVITY; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; SYNTHESIS;

PLASMODIUM FALCIPARUM;

EID: 0037463811     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(03)00240-0     Document Type: Article

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