Effect of 9,10-cyclic acetal stereochemistry on feasible operation of the α-ketol rearrangement in highly functionalized paclitaxel (Taxol) precursors

Journal of Organic Chemistry

Volumn 68, Issue 6, 2003, Pages 2266-2275

  Paquette, Leo A ^a   Hofferberth, John E ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RELATIVE STRAIN ENERGY;

ISOMERIZATION; ISOMERS; SYNTHESIS (CHEMICAL);

STEREOCHEMISTRY;

9,10 CYCLIC ACETAL; ACETAL; ACETAL DERIVATIVE; ALPHA KETOL; KETOL; PACLITAXEL; UNCLASSIFIED DRUG;

ARTICLE; CALCULATION; CHEMICAL STRUCTURE; ENERGY; ISOMERISM; OXYGENATION; PRECURSOR; REACTION ANALYSIS; STEREOCHEMISTRY; STEREOISOMERISM; SYNTHESIS;

ACETALS; CATALYSIS; COMBINATORIAL CHEMISTRY TECHNIQUES; CYCLIZATION; INDICATORS AND REAGENTS; KETONES; MOLECULAR STRUCTURE; NEURAMINIDASE; OXIDATION-REDUCTION; PACLITAXEL; STEREOISOMERISM;

EID: 0037459718     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo020627v     Document Type: Article

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