A dominant negative mutant β2-microglobulin blocks the extracellular folding of a major histocompatibility complex class I heavy chain

Journal of Biological Chemistry

Volumn 278, Issue 8, 2003, Pages 5630-5638

  Hill, Dawn M ^b   Kasliwal, Tina ^b   Schwarz, Elie ^b   Hebert, Andrea M ^b   Chen, Trina ^b   Gubina, Elena ^b   Zhang, Lei ^b   Kozlowski, Steven ^a  

^a CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; PROTEINS; TOXIC MATERIALS;

NEGATIVE MUTANTS;

MOLECULAR BIOLOGY;

BETA 2 MICROGLOBULIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; HLA ANTIGEN CLASS 1; PRIMER DNA; RECOMBINANT PROTEIN;

ACCURACY; ANIMAL CELL; ARTICLE; COMPLEX FORMATION; CYTOTOXIC T LYMPHOCYTE; MODEL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN STRUCTURE; STRUCTURE ANALYSIS; THERMODYNAMICS; AMINO ACID SUBSTITUTION; ANIMAL; CELL CULTURE; CELL LINE; CHEMISTRY; DOMINANT GENE; GENE; GENETIC TRANSFECTION; GENETICS; HUMAN; IMMUNOLOGY; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PROTEIN SECONDARY STRUCTURE; SITE DIRECTED MUTAGENESIS; T CELL LYMPHOMA;

ANIMALIA;

AMINO ACID SUBSTITUTION; ANIMALS; BASE SEQUENCE; BETA 2-MICROGLOBULIN; CELL LINE; CLONING, MOLECULAR; DNA PRIMERS; GENES, DOMINANT; GENES, MHC CLASS I; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; LYMPHOMA, T-CELL; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; POLYMERASE CHAIN REACTION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; T-LYMPHOCYTES, CYTOTOXIC; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0037458575     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M208381200     Document Type: Article

References (68)

1. Townsend, A., and Bodmer, H. (1989) Annu. Rev. Immunol. 7, 601-624
2. Jones, E. Y., Tormo, J., Reid, S. W., and Stuart, D. I. (1998) Immunol. Rev. 163, 121-128
3. Germain, R. N., and Margulies, D. H. (1993) Annu. Rev. Immunol. 11, 403-450
4. Ljunggren, H. G., and Thorpe, C. J. (1996) Histol. Histopathol. 11, 267-274
5. Ozato, K., Evans, G. A., Shykind, B., Margulies, D. H., and Seidman, J. G. (1983) Proc. Natl. Acad. Sci. U. S. A. 80, 2040-2043
6. Bjorkman, P. J., Saper, M. A., Samraoui, B., Bennett, W. S., Strominger, J. L., and Wiley, D. C. (1987) Nature 329, 512-518
7. Davis, M. M., Boniface, J. J., Reich, Z., Lyons, D., Hampl, J., Arden, B., and Chien, Y. (1998) Annu. Rev. Immunol. 16, 523-544
8. Saper, M. A., Bjorkman, P. J., and Wiley, D. C. (1991) J. Mol. Biol. 219, 277-319
9. Santos-Aguado, J., Biro, P. A., Fuhrmann, U., Strominger, J. L., and Barbosa, J. A. (1987) Mol. Cell. Biol. 7, 982-990
10. Ribaudo, R. K., and Margulies, D. H. (1995) J. Immunol. 155, 3481-3493
11. Salter, R. D. (1992) Hum. Immunol. 35, 40-49
12. Seong, R. H., Clayberger, C. A., Krensky, A. M., and Parnes, J. R. (1988) J. Exp. Med. 167, 288-299
13. Zijlstra, M., Bix, M., Simister, N. E., Loring, J. M., Raulet, D. H., and Jaenisch, R. (1990) Nature 344, 742-746
14. Allen, H., Fraser, J., Flyer, D., Calvin, S., and Flavell, R. (1986) Proc. Natl. Acad. Sci. U. S. A. 83, 7447-7451
15. Bix, M., and Raulet, D. (1992) J. Exp. Med. 176, 829-834
16. Solheim, J. C., Johnson, N. A., Carreno, B. M., Lie, W. R., and Hansen, T. H. (1995) Eur. J. Immunol. 25, 3011-3016
17. Fink, A. L. (1999) Physiol. Rev. 79, 425-449
18. Solheim, J. C. (1999) Immunol. Rev. 172, 11-19
19. Cresswell, P., Bangia, N., Dick, T., and Diedrich, G. (1999) Immunol. Rev. 172, 21-28
20. Rock, K. L., Gramm, C., and Benacerraf, B. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 4200-4204
21. Otten, G. R., Bikoff, E., Ribaudo, R. K., Kozlowski, S., Margulies, D. H., and Germain, R. N. (1992) J. Immunol. 148, 3723-3732
22. Elliott, T., Cerundolo, V., Elvin, J., and Townsend, A. (1991) Nature 351, 402-406
23. Elliott, T., Elvin, J., Cerundolo, V., Allen, H., and Townsend, A. (1992) Eur. J. Immunol. 22, 2085-2091
24. Hyafil, F., and Strominger, J. L. (1979) Proc. Natl. Acad. Sci. U. S. A. 76, 5834-5838
25. Parker, K. C., and Strominger, J. L. (1985) Biochemistry 24, 5543-5550
26. Hochman, J. H., Shimizu, Y., DeMars, R., and Edidin, M. (1988) J. Immunol. 140, 2322-2329
27. Pedersen, L. O., Hansen, A. S., Olsen, A. C., Gerwien, J., Nissen, M. H., and Buus, S. (1994) Scand. J. Immunol. 39, 64-72
28. Shields, M. J., Moffat, L. E., and Ribaudo, R. K. (1998) Mol. Immunol. 35, 919-928
29. Whitman, M. C., Strohmaier, J., O'Boyle, K., Tingem, J. M., Wilkinson, Y., Goldstein, J., Chen, T., Brorson, K., Brunswick, M., and Kozlowski, S. (2000) Mol. Immunol. 37, 141-149
30. Hebert, A. M., Strohmaier, J., Whitman, M. C., Chen, T., Gubina, E., Hill, D. M., Lewis, M. S., and Kozlowski, S. (2001) Biochemistry 40, 5233-5242
31. Herskowitz, I. (1987) Nature 329, 219-222
32. Perlmutter, R. M., and Alberola-Ila, J. (1996) Curr. Opin. Immunol. 8, 285-290
33. Gill, S. C., and von Hippel, P. H. (1989) Anal. Biochem. 182, 319-326
34. Shields, M. J., Assefi, N., Hodgson, W., Kim, E. J., and Ribaudo, R. K. (1998) J. Immunol. 160, 2297-2307
35. Shields, M. J., Kubota, R., Hodgson, W., Jacobson, S., Biddison, W. E., and Ribaudo, R. K. (1998) J. Biol. Chem. 273, 28010-28018
36. Horton, R. M., Cai, Z. L., Ho, S. N., and Pease, L. R. (1990) Biotechniques 8, 528-535
37. Bikoff, E. K., Otten, G. R., and Robertson, E. J. (1991) Eur. J. Immunol. 21, 1997-2004
38. Chen, W., Yewdell, J. W., Levine, R. L., and Bennink, J. R. (1999) J. Exp. Med. 189, 1757-1764
39. Kozlowski, S., Takeshita, T., Boehncke, W. H., Takahashi, H., Boyd, L. F., Germain, R. N., Berzofsky, J. A., and Margulies, D. H. (1991) Nature 349, 74-77
40. Takahashi, H., Cohen, J., Hosmalin, A., Cease, K. B., Houghten, R., Cornette, J. L., DeLisi, C., Moss, B., Germain, R. N., and Berzofsky, J. A. (1988) Proc. Natl. Acad. Sci. U. S. A. 85, 3105-3109
41. Kozlowski, S., Corr, M., Takeshita, T., Boyd, L. F., Pendleton, C. D., Germain, R. N., Berzofsky, J. A., and Margulies, D. H. (1992) J. Exp. Med. 175, 1417-1422
42. Takeshita, T., Takahashi, H., Kozlowski, S., Ahlers, J. D., Pendleton, C. D., Moore, R. L., Nakagawa, Y., Yokomuro, K., Fox, B. S., and Margulies, D. H., et al. (1995) J. Immunol. 154, 1973-1986
43. Johnsson, B., Lofas, S., and Lindquist, G. (1991) Anal. Biochem. 198, 268-277
44. Ashwell, J. D., Cunningham, R. E., Noguchi, P. D., and Hernandez, D. (1987) J. Exp. Med. 165, 173-194
45. Li, H., Natarajan, K., Malchiodi, E. L., Margulies, D. H., and Mariuzza, R. A. (1998) J. Mol. Biol. 283, 179-191
46. Fukazawa, T., Hermann, E., Edidin, M., Wen, J., Huang, F., Kellner, H., Floege, J., Farahmandian, D., Williams, K. M., and Yu, D. T. (1994) J. Immunol. 153, 3543-3550
47. Achour, A., Persson, K., Harris, R. A., Sundback, J., Sentman, C. L., Lindqvist, Y., Schneider, G., and Karre, K. (1998) Immunity 9, 199-208
48. Tormo, J., Natarajan, K., Margulies, D. H., and Mariuzza, R. A. (1999) Nature 402, 623-631
49. Shields, M. J., Hodgson, W., and Ribaudo, R. K. (1999) Mol. Immunol. 36, 561-573
50. Garboczi, D. N., Madden, D. R., and Wiley, D. C. (1994) J. Mol. Biol. 239, 581-587
51. Ljunggren, H. G., Stam, N. J., Ohlen, C., Neefjes, J. J., Hoglund, P., Heemels, M. T., Bastin, J., Schumacher, T. N., Townsend, A., and Karre, K., et al. (1990) Nature 346, 476-480
52. Abastado, J. P., Casrouge, A., and Kourilsky, P. (1993) J. Immunol. 151, 3569-3575
53. Noun, G., Reboul, M., Abastado, J. P., Jaulin, C., Kourilsky, P., and Pla, M. (1996) J. Immunol. 157, 2455-2461
54. Anderson, K. S., Alexander, J., Wei, M., and Cresswell, P. (1993) J. Immunol. 151, 3407-3419
55. Smith, M. H., and Barber, B. H. (1990) Mol. Immunol. 27, 169-180
56. Elliott, T. (1991) Immunol. Today 12, 386-388
57. Ribaudo, R. K., and Margulies, D. H. (1992) J. Immunol. 149, 2935-2944
58. Wang, J., Whitman, M. C., Natarajan, K., Tormo, J., Mariuzza, R. A., and Margulies, D. H. (2002) J. Biol. Chem. 277, 1433-1442
59. Michaelsson, J., Achour, A., Rolle, A., and Karre, K. (2001) J. Immunol. 166, 7327-7334
60. Glick, M., Price, D. A., Vuidepot, A. L., Andersen, T. B., Hutchinson, S. L., Laugel, B., Sewell, A. K., Boulter, J. M., Dunbar, P. R., Cerundolo, V., Oxenius, A., Bell, J. I., Richards, W. G., and Jakobsen, B. K. (2002) J. Biol. Chem. 277, 20840-20846
61. Rock, K. L., Gamble, S., Rothstein, L., Gramm, C., and Benacerraf, B. (1991) Cell 65, 611-620
62. Smith, J. D., Lie, W. R., Gorka, J., Myers, N. B., and Hansen, T. H. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 7767-7771
63. Vitiello, A., Potter, T. A., and Sherman, L. A. (1990) Science 250, 1423-1426
64. Rock, K. L., Rothstein, L. E., Gamble, S. R., and Benacerraf, B. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 7517-7521
65. Kane, K. P., Sherman, L. A., and Mescher, M. F. (1991) Eur. J. Immunol. 21, 2289-2292
66. Sherman, L. A., Burke, T. A., and Biggs, J. A. (1992) J. Exp. Med. 175, 1221-1226
67. Falo, L. D., Jr., Colarusso, L. J., Benacerraf, B., and Rock, K. L. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 8347-8350
68. Kozlowski, S., Corr, M., Shirai, M., Boyd, L. F., Pendleton, C. D., Berzofsky, J. A., and Margulies, D. H. (1993) J. Immunol. 151, 4033-4044