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Volumn 964, Issue 1, 2003, Pages 9-20

Non-adrenergic exploratory behavior induced by moxonidine at mildly hypotensive doses

Author keywords

2 Adrenoceptor; Anti depressant; Anxiety; Blood pressure; Exploration; Guanabenz; Imidazoline receptors; Moxonidine

Indexed keywords

6 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 1H 3 BENZAZEPINE; ALPHA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; GUANABENZ; MOXONIDINE; SODIUM CHLORIDE;

EID: 0037458517     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(02)03754-X     Document Type: Article
Times cited : (10)

References (58)
  • 1
    • 0023712512 scopus 로고
    • General pharmacology of the novel centrally acting antihypertensive agent moxonidine
    • Armah B.I., Hofferber E., Stenzel W. General pharmacology of the novel centrally acting antihypertensive agent moxonidine. Arzneim.-Forsch. 38:1988;1426-1434.
    • (1988) Arzneim.-Forsch. , vol.38 , pp. 1426-1434
    • Armah, B.I.1    Hofferber, E.2    Stenzel, W.3
  • 2
    • 0013017883 scopus 로고
    • Relaxation response, physiology, history and clinical applications
    • Adelman G. Boston: Birkhauser
    • Benson H. Relaxation response, physiology, history and clinical applications. Adelman G. Encyclopedia of Neuroscience. Vol. II:1987;1045-1047 Birkhauser, Boston.
    • (1987) Encyclopedia of Neuroscience , vol.2 , pp. 1045-1047
    • Benson, H.1
  • 4
    • 0025718614 scopus 로고
    • Characterization of the alpha-2C adrenergic receptor subtype in the opossum kidney and in the OK cell line
    • Blaxall H.S., Murphy T.J., Baker J.C., Ray C., Bylund D.B. Characterization of the alpha-2C adrenergic receptor subtype in the opossum kidney and in the OK cell line. J. Pharmacol. Exp. Ther. 259:1991;323-329.
    • (1991) J. Pharmacol. Exp. Ther. , vol.259 , pp. 323-329
    • Blaxall, H.S.1    Murphy, T.J.2    Baker, J.C.3    Ray, C.4    Bylund, D.B.5
  • 5
    • 0026473764 scopus 로고
    • Neuropharmacologic and behavioral actions of clonidine: Interactions with central neurotransmitters
    • Academic Press
    • Buccafusco J.J. Neuropharmacologic and behavioral actions of clonidine: Interactions with central neurotransmitters. International Review of Neurobiology. Vol. 33:1992;55-107 Academic Press.
    • (1992) International Review of Neurobiology , vol.33 , pp. 55-107
    • Buccafusco, J.J.1
  • 7
    • 0027092516 scopus 로고
    • Moxonidine. A review of its pharmacology, and therapeutic use in essential hypertension
    • Chrisp P., Faulds D. Moxonidine. A review of its pharmacology, and therapeutic use in essential hypertension. Drugs. 44:1992;993-1012.
    • (1992) Drugs , vol.44 , pp. 993-1012
    • Chrisp, P.1    Faulds, D.2
  • 8
    • 0034746694 scopus 로고    scopus 로고
    • 2 agonist clonidine modulates behavioural and neuroanatomical correlates of human attentional orienting and alerting
    • 2 agonist clonidine modulates behavioural and neuroanatomical correlates of human attentional orienting and alerting. Cereb. Cortex. 11:2001;73-84.
    • (2001) Cereb. Cortex , vol.11 , pp. 73-84
    • Coull, J.T.1    Nobre, A.C.2    Frith, C.D.3
  • 9
    • 0019199013 scopus 로고
    • Preliminary report of a simple animal behavior model for the anxiolytic effects of benzodiazepines
    • Crawley J., Goodwin F.K. Preliminary report of a simple animal behavior model for the anxiolytic effects of benzodiazepines. Pharmacol. Biochem. Behav. 13:1980;167-170.
    • (1980) Pharmacol. Biochem. Behav. , vol.13 , pp. 167-170
    • Crawley, J.1    Goodwin, F.K.2
  • 12
    • 0022446133 scopus 로고
    • Behavioral effects of neurotensin in the open field: Structure-activity studies
    • Elliott P.J., Chan J., Parker Y.M., Nemeroff C.B. Behavioral effects of neurotensin in the open field: structure-activity studies. Brain Res. 381:1986;259-265.
    • (1986) Brain Res. , vol.381 , pp. 259-265
    • Elliott, P.J.1    Chan, J.2    Parker, Y.M.3    Nemeroff, C.B.4
  • 13
    • 0031278681 scopus 로고    scopus 로고
    • 1-imidazoline-binding site is a functional receptor mediating vasodepression via the ventral medulla
    • 1-imidazoline-binding site is a functional receptor mediating vasodepression via the ventral medulla. Am. J. Physiol. 42:1997;R1572-R1579.
    • (1997) Am. J. Physiol. , vol.42 , pp. 1572-R1579
    • Ernsberger, P.1    Haxhiu, M.A.2
  • 15
    • 0033992159 scopus 로고    scopus 로고
    • 2 adrenergic receptor agonist, synergizes with morphine and deltorphin II to inhibit substance P-induced behavior in mice
    • 2 adrenergic receptor agonist, synergizes with morphine and deltorphin II to inhibit substance P-induced behavior in mice. Pain. 84:2000;13-20.
    • (2000) Pain , vol.84 , pp. 13-20
    • Fairbanks, C.A.1    Posthumus, I.J.2    Kitto, K.F.3    Stone, L.S.4    Wilcox, G.L.5
  • 16
    • 0032589078 scopus 로고    scopus 로고
    • 2-adrenergic and imidazoline receptor agonist, produces spinal antinociception in mice
    • 2-adrenergic and imidazoline receptor agonist, produces spinal antinociception in mice. J. Pharmacol. Exp. Ther. 290:1999;403-412.
    • (1999) J. Pharmacol. Exp. Ther. , vol.290 , pp. 403-412
    • Fairbanks, C.A.1    Wilcox, G.L.2
  • 17
    • 0028986474 scopus 로고
    • 1 imidazoline receptor agonist, moxonidine, on gastric secretion and gastric mucosal injury in rats
    • 1 imidazoline receptor agonist, moxonidine, on gastric secretion and gastric mucosal injury in rats. Br. J. Pharmacol. 114:1995;751-754.
    • (1995) Br. J. Pharmacol. , vol.114 , pp. 751-754
    • Glavin, G.B.1    Smyth, D.D.2
  • 18
  • 19
    • 0021183219 scopus 로고
    • 2-adrenoceptor agonists and antagonists in a maze-exploration model of 'fear'-motivated behaviour
    • 2-adrenoceptor agonists and antagonists in a maze-exploration model of 'fear'-motivated behaviour. Naunyn Schmiedebergs Arch. Pharmacol. 327:1984;1-5.
    • (1984) Naunyn Schmiedebergs Arch. Pharmacol. , vol.327 , pp. 1-5
    • Handley, S.L.1    Mithani, S.2
  • 21
    • 0032775823 scopus 로고    scopus 로고
    • 2-receptors involved in the cardiovascular actions of centrally acting antihypertensive agents
    • 2-receptors involved in the cardiovascular actions of centrally acting antihypertensive agents. Ann. N Y Acad. Sci. 881:1999;279-286.
    • (1999) Ann. N Y Acad. Sci. , vol.881 , pp. 279-286
    • Head, G.A.1
  • 24
    • 0002228762 scopus 로고    scopus 로고
    • Harmane, norharmane and tetrahydro beta-carboline have high affinity for rat imidazoline binding sites
    • Hudson A., Price R., Tyacke R.J., Lalies M.D., Parker C.A., Nutt D.J. Harmane, norharmane and tetrahydro beta-carboline have high affinity for rat imidazoline binding sites. Br. J. Pharmacol. 126:1999;2P.
    • (1999) Br. J. Pharmacol. , vol.126
    • Hudson, A.1    Price, R.2    Tyacke, R.J.3    Lalies, M.D.4    Parker, C.A.5    Nutt, D.J.6
  • 27
    • 0023255981 scopus 로고
    • The use of a plus-maze to measure anxiety in the mouse
    • Lister R.G. The use of a plus-maze to measure anxiety in the mouse. Psychopharmacology. 92:1987;180-185.
    • (1987) Psychopharmacology , vol.92 , pp. 180-185
    • Lister, R.G.1
  • 28
    • 0024509537 scopus 로고
    • Mechanism of action of clonidine in the forced-swimming test in mice
    • Malinge M., Colombel M.C., Bourin M. Mechanism of action of clonidine in the forced-swimming test in mice. Encephale. 15:1989;37-41.
    • (1989) Encephale , vol.15 , pp. 37-41
    • Malinge, M.1    Colombel, M.C.2    Bourin, M.3
  • 29
    • 0014691991 scopus 로고
    • Circulatory effects at rest and exercise of clonidine, an imidazoline derivative with hypotensive properties
    • Muir A.L., Burton J.L., Lawrie D.M. Circulatory effects at rest and exercise of clonidine, an imidazoline derivative with hypotensive properties. Lancet. 2:1969;181-184.
    • (1969) Lancet , vol.2 , pp. 181-184
    • Muir, A.L.1    Burton, J.L.2    Lawrie, D.M.3
  • 31
    • 0022374863 scopus 로고
    • Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat
    • Pellow S., Chopin P., File S.E., Briley M. Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. J. Neurosci. Methods. 14:1985;149-167.
    • (1985) J. Neurosci. Methods , vol.14 , pp. 149-167
    • Pellow, S.1    Chopin, P.2    File, S.E.3    Briley, M.4
  • 34
    • 0027716921 scopus 로고
    • Non-adrenergic imidazoline binding sites on human platelets
    • Piletz J.E., Sletten K. Non-adrenergic imidazoline binding sites on human platelets. J. Pharmacol. Exp. Ther. 267:1993;1493-1502.
    • (1993) J. Pharmacol. Exp. Ther. , vol.267 , pp. 1493-1502
    • Piletz, J.E.1    Sletten, K.2
  • 36
    • 0017651126 scopus 로고
    • Behavioral despair in mice: A primary screening test for antidepressants
    • Porsolt R.D., Bertin A., Jalfre M. Behavioral despair in mice: a primary screening test for antidepressants. Arch. Int. Pharmacodyn. Ther. 229:1977;327-336.
    • (1977) Arch. Int. Pharmacodyn. Ther. , vol.229 , pp. 327-336
    • Porsolt, R.D.1    Bertin, A.2    Jalfre, M.3
  • 37
    • 0031034267 scopus 로고    scopus 로고
    • Relationship between imidazoline and guanidinium receptive sites and monoamine oxidase A and B
    • Raddatz R., Lanier S.M. Relationship between imidazoline and guanidinium receptive sites and monoamine oxidase A and B. Neurochem. Int. 30:1997;109-117.
    • (1997) Neurochem. Int. , vol.30 , pp. 109-117
    • Raddatz, R.1    Lanier, S.M.2
  • 40
    • 0028911164 scopus 로고
    • Excess catecholamines and the metabolic syndrome: Should central imidazoline receptors be a therapeutic target?
    • Rupp H., Jacob R. Excess catecholamines and the metabolic syndrome: should central imidazoline receptors be a therapeutic target? Med. Hypotheses. 44:1995;217-225.
    • (1995) Med. Hypotheses , vol.44 , pp. 217-225
    • Rupp, H.1    Jacob, R.2
  • 43
    • 0031668060 scopus 로고    scopus 로고
    • Safety and tolerability of moxonidine in the treatment of hypertension
    • Schachter M., Luszick J., Jager B., Verboom C., Sohlke E. Safety and tolerability of moxonidine in the treatment of hypertension. Drug Saf. 19:1998;191-203.
    • (1998) Drug Saf. , vol.19 , pp. 191-203
    • Schachter, M.1    Luszick, J.2    Jager, B.3    Verboom, C.4    Sohlke, E.5
  • 44
    • 0035815077 scopus 로고    scopus 로고
    • Evaluation of the alpha2C-adrenoceptor as a neuropsychiatric drug target studies in transgenic mouse models
    • Scheinin M., Sallinen J., Haapalinna A. Evaluation of the alpha2C-adrenoceptor as a neuropsychiatric drug target studies in transgenic mouse models. Life Sci. 68:2001;2277-2285.
    • (2001) Life Sci. , vol.68 , pp. 2277-2285
    • Scheinin, M.1    Sallinen, J.2    Haapalinna, A.3
  • 46
    • 0035399969 scopus 로고    scopus 로고
    • The alpha(2a)-adrenergic receptor plays a protective role in mouse behavioral models of depression and anxiety
    • Schramm N.L., McDonald M.P., Limbird L.E. The alpha(2a)-adrenergic receptor plays a protective role in mouse behavioral models of depression and anxiety. J. Neurosci. 21:2001;4875-4882.
    • (2001) J. Neurosci. , vol.21 , pp. 4875-4882
    • Schramm, N.L.1    McDonald, M.P.2    Limbird, L.E.3
  • 48
    • 0017182862 scopus 로고
    • Guanabenz effects on blood pressure and non-invasive parameters of cardiac performance in patients with hypertension
    • Shah R.S., Walker B.R., Vanov S.K., Helfant R.H. Guanabenz effects on blood pressure and non-invasive parameters of cardiac performance in patients with hypertension. Clin. Pharmacol. Ther. 19:1976;732-737.
    • (1976) Clin. Pharmacol. Ther. , vol.19 , pp. 732-737
    • Shah, R.S.1    Walker, B.R.2    Vanov, S.K.3    Helfant, R.H.4
  • 49
    • 0033597775 scopus 로고    scopus 로고
    • Efficient liver-specific deletion of a floxed human angiotensinogen transgene by adenoviral delivery of cre-recombinase in vivo
    • Stec D.E., Davisson R.L., Haskell R.E., Davidson B.L., Sigmund C.D. Efficient liver-specific deletion of a floxed human angiotensinogen transgene by adenoviral delivery of cre-recombinase in vivo. J. Biol. Chem. 274:1999;21285-21290.
    • (1999) J. Biol. Chem. , vol.274 , pp. 21285-21290
    • Stec, D.E.1    Davisson, R.L.2    Haskell, R.E.3    Davidson, B.L.4    Sigmund, C.D.5
  • 50
    • 0030608822 scopus 로고    scopus 로고
    • D3 dopamine receptor-deficient mouse: Evidence for reduced anxiety
    • Steiner H., Fuchs S., Accili D. D3 dopamine receptor-deficient mouse: evidence for reduced anxiety. Physiol. Behav. 63:1997;137-141.
    • (1997) Physiol. Behav. , vol.63 , pp. 137-141
    • Steiner, H.1    Fuchs, S.2    Accili, D.3
  • 51
    • 0037125987 scopus 로고    scopus 로고
    • Heterozygous alpha2A-adrenergic receptor mice unveil unique therapeutic benefits of partial agonists
    • Tan C.M., Wilson M.H., MacMillan L.B., Kobilka B.K., Limbird L.E. Heterozygous alpha2A-adrenergic receptor mice unveil unique therapeutic benefits of partial agonists. Proc. Natl. Acad. Sci. USA. 99:2002;12471-12476.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 12471-12476
    • Tan, C.M.1    Wilson, M.H.2    MacMillan, L.B.3    Kobilka, B.K.4    Limbird, L.E.5
  • 52
    • 0034678538 scopus 로고    scopus 로고
    • Alpha(2)-adrenergic receptors are not required for central anti-hypertensive action of moxonidine in mice
    • Tolentino-Silva F.P., Haxhiu M.A., Waldbaum S., Dreshaj I.A., Ernsberger P. Alpha(2)-adrenergic receptors are not required for central anti-hypertensive action of moxonidine in mice. Brain Res. 862:2000;26-35.
    • (2000) Brain Res. , vol.862 , pp. 26-35
    • Tolentino-Silva, F.P.1    Haxhiu, M.A.2    Waldbaum, S.3    Dreshaj, I.A.4    Ernsberger, P.5
  • 53
    • 0024158498 scopus 로고
    • Thigmotaxis as a test for anxiolytic activity in rats
    • Treit D., Fundytus M. Thigmotaxis as a test for anxiolytic activity in rats. Pharmacol. Biochem. Behav. 31:1988;959-962.
    • (1988) Pharmacol. Biochem. Behav. , vol.31 , pp. 959-962
    • Treit, D.1    Fundytus, M.2
  • 54
    • 0030608948 scopus 로고    scopus 로고
    • 1) receptors as targets of centrally acting antihypertensives: Moxonidine and rilmenidine
    • 1) receptors as targets of centrally acting antihypertensives: moxonidine and rilmenidine. J. Hypertens. 15:1997;117-125.
    • (1997) J. Hypertens. , vol.15 , pp. 117-125
    • Van Zwieten, P.A.1
  • 55
    • 0034107808 scopus 로고    scopus 로고
    • Moxonidine, a selective imidazoline-1 receptor agonist, suppresses the effects of ethanol withdrawal on the acoustic startle response in rats
    • Vandergriff J., Kallman M.J., Rasmussen K. Moxonidine, a selective imidazoline-1 receptor agonist, suppresses the effects of ethanol withdrawal on the acoustic startle response in rats. Biol. Psychiatry. 47:2000;874-879.
    • (2000) Biol. Psychiatry , vol.47 , pp. 874-879
    • Vandergriff, J.1    Kallman, M.J.2    Rasmussen, K.3
  • 56
    • 0018187319 scopus 로고
    • Interactions between clonidine and antidepressant drugs: A method for identifying antidepressant-like agents
    • Von Voigtlander P.F., Triezenberg H.J., Losey E.G. Interactions between clonidine and antidepressant drugs: a method for identifying antidepressant-like agents. Neuropharmacology. 17:1978;375-381.
    • (1978) Neuropharmacology , vol.17 , pp. 375-381
    • Von Voigtlander, P.F.1    Triezenberg, H.J.2    Losey, E.G.3


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