Activation of phosphatidylcholine-selective phospholipase C by I1-imidazoline receptors in PC12 cells and rostral ventrolateral medulla

Brain Research

Volumn 749, Issue 2, 1997, Pages 335-339

  Separovic, Duska ^a   Kester, Mark ^a   Haxhiu, Musa A ^a   Ernsberger, Paul ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

D609; diacylglycerol; I1 imidazoline receptor; moxonidine; PC PLC; PC12 cell; phosphocholine; rostral ventrolateral medulla; SHR rat

Indexed keywords

DIACYLGLYCEROL; EFAROXAN; ENZYME INHIBITOR; IMIDAZOLINE RECEPTOR; IMIDAZOLINE RECEPTOR AGONIST; MOXONIDINE; PHOSPHOLIPASE C; TRICYCLO[4.3.0.1]DECAN 9 YL XANTHOGENATE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE; CELL CULTURE; CONTROLLED STUDY; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MEDULLA OBLONGATA; NONHUMAN; PHEOCHROMOCYTOMA; PRIORITY JOURNAL; RAT; SPONTANEOUSLY HYPERTENSIVE RAT;

ADRENAL GLAND NEOPLASMS; ANIMALS; ANTIHYPERTENSIVE AGENTS; BRIDGED COMPOUNDS; DIGLYCERIDES; ENZYME ACTIVATION; IMIDAZOLES; MEDULLA OBLONGATA; MICROINJECTIONS; MODELS, BIOLOGICAL; NERVE GROWTH FACTORS; PC12 CELLS; PHEOCHROMOCYTOMA; PHOSPHOLIPASE C; RATS; RATS, INBRED SHR; RECEPTORS, DRUG; SIGNAL TRANSDUCTION; THIONES;

EID: 0031047272     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(96)01372-8     Document Type: Article

References (34)

1. Baldi, E., Musial, A. and Kester, M., Endothelin stimulates phosphatidylcholine hydrolysis through both PLC and PLD pathways in mesangial cells, Am. J. Physiol., 266 (1994) F957-65.
2. Bousquet, P., Feldman, J., Bloch, R. and Schwartz, J., Central cardiovascular effects of α-adrenergic drugs: Differences between catecholamines and imidazolines, J. Pharmacol. Exp. Ther., 230 (1984) 232-236.
3. Bousquet, P. and Guertzenstein, P.G., Localization of the central cardiovascular action of clonidine, Br. J. Pharmacol., 49 (1973) 573-579.
4. Chan, C.K.S., Sannajust, F. and Head, G.A., Role of imidazoline receptors in the cardiovascular actions of moxonidine, rilmenidine and clonidine in conscious rabbits, J. Pharmacol. Exp. Ther., 276 (1996) 411-420.
5. 2-adrenoceptors in the human central nervous system, Neuroscience, 59 (1994) 589-598.
6. 2-adrenergic receptor subtypes in a cell type-specific manner, J. Biol. Chem., 267 (1992) 24045-24052.
7. 1 receptors in the ventrolateral medulla and their role in cardiorespiratory control. In O. Trouth, R. Millis, H. Kiwell-Schone and M. Schläfke (Eds.) Ventral Brainstem Mechanisms and Control Functions, Marcel Decker, New York, 1995, pp. 319-358.
8. 1-imidazoline sites, J. Pharmacol. Exp. Ther., 264 (1993) 172-182.
9. Ernsberger, P., Giuliano, R., Willette, R.N. and Reis, D.J., Role of imidazole receptors in the vasodepressor response to clonidine analogs in the rostral ventrolateral medulla, J. Pharmacol. Exp. Ther., 253 (1990) 408-418.
10. 1-imidazoline receptors: Definition, characterization, distribution and transmembrane signalling, Ann. N.Y. Acad. Sci., 763 (1995) 22-42.
11. 2-adrenoceptors in the ventrolateral medulla, Eur. J. Pharmacol., 134 (1987) 1-13.
12. 1-Imidazoline receptors mediate arachidonic acid release from PC12 pheochromocytoma cells, FASEB J., 9 (1995) A114 (Abstract).
13. 1-imidazoline binding sites, Neurochem. Int., 30 (1997) 17-23.
14. Exton, J.H., Phosphatidylcholine breakdown and signal transduction, Biochim. Biophys. Acta, 1212 (1994) 26-42.
15. Felsen, D., Ernsberger, P., Sutaria, P.M., Nejat, R.J., Nguyen, P., May, M., Breslin, D.S., Marion, D.N. and Vaughan, E.D., Jr., Identification, localization and functional analysis of imidazoline and α-adrenergic receptors in canine prostate, J. Pharmacol Exp. Ther., 268 (1994) 1063-1071.
16. Galella, G., Medini, L., Stragliotto, E., Stefanini, P., Rise, P., Tremoli, E. and Galli, C., In human monocytes interleukin-1 stimulates a phospholipase C active on phosphatidylcholine and inactive on phosphatidylinositol, Biochem. Pharmacol., 44 (1992) 715-720.
17. 1-imidazoline receptors in the rostal ventrolateral medulla, J. Cardiovasc. Pharmacol., 24 (Suppl. 1) (1994) S1-S8.
18. 1-imidazoline receptor activation on responses of hypoglossal and phrenic nerve to chemical stimulation, Ann. N.Y. Acad. Sci., 763 (1995) 445-462.
19. Kester, M., Simonson, M.S., Mene, P. and Sedor, J.R., Interleukin-1 generates transmembrane signals from phospholipids through novel pathways in cultured rat mesangial cells, J. Clin. Invest., 83 (1989) 718-723.
20. Lassegue, B., Alexander, R.W., Clark, M. and Griendling, K.K., Angiotensin II-induced phosphatidylcholine hydrolysis in cultured vascular smooth-muscle cells, Biochem. J., 276 (1991) 19-25.
21. 2-Adrenergic, but not imidazole, agonists activate NaCl cotransport in rabbit tracheal epithelial cells, Am. J. Physiol. Cell Physiol., 264 (1993) C568-C576.
22. Michel, M.C. and Erasberger, P., Keep an eye on the I site: Imidazoline-preferring receptors, Trends Pharmacol. Sci., 13 (1992) 369-370.
23. Murthy, K.S. and Makhlouf, G.M., Agonist-mediated activation of phosphatidylcholine-specific phospholipase C and D in intestinal smooth muscle, Mol. Pharmacol., 48 (1995) 293-304.
24. Müller-Decker, K., Interruption of TPA-induced signals by an antiviral and antitumoral xanthate compound: Inhibition of a phospholipase C-type reaction, Biochem. Biophys. Res. Comm., 162 (1989) 198-205.
25. Piletz, J.E. and Sletten, K., Nonadrenergic imidazoline binding sites on human platelets, J. Pharmacol. Exp. Ther., 267 (1993) 1493-1502.
26. Rao, P. and Mufson, R.A., Human interleukin-3 stimulates a phosphatidylcholine specific phospholipase C and protein kinase C translocation, Cancer Res., 54 (1994) 777-783.
27. Regunathan, S., Evinger, M.J., Meeley, M.P. and Reis, D.J., Effects of clonidine and other imidazole-receptor binding agents on second messenger systems and calcium influx in bovine adrenal chromaffin cells. Biochem. Pharmacol., 42 (1991) 2011-2018.
28. Regunathan, S. and Reis, D.J., Effects of moxonidine, an imidazoline antihypertensive agent, on second messenger systems in rat brain, Eur. J. Pharmacol. Mol. Pharmacol., 269 (1994) 273-276.
29. Schutze, S., Potthoff, K., Machleidt, T., Berkovic, D., Wiegmann, K. and Krönke, M., TNF activates NF-kB by phosphatidylcholine-specific phospholipase C-induced acidic sphingomyclin breakdown, Cell. 71 (1992) 765-776.
30. 1, subtype couple to phosphatidylcholine-selective phospholipase C (PC-PLC) in PC12 pheochromocytoma cells. FASEB J. 10 ( 1996) A416 (Abstract).
31. 1-imidazoline receptors to diacylglyceride accumulation in PC12 rat pheochromocytoma cells. Mol. Pharmacol., 49 (1996) 668-675.
32. 2-imidazoline binding sites on monoamine oxidases, J. Biol. Chem., 270 (1995) 9856-9861.
33. Tesson, F., Prip-Buus, C., Lemoine, A., Pegorier, J.-P. and Parini, A., Subcellular distribution of imidazoline-guanidinium-receptive sites in human and rabbit liver. Major localization to the mitochondrial outer membrane, J. Biol. Chem., 266 (1991) 155-160.
34. Yavin, E., Regulation of phospholipid metabolism in differentiating cells from rat brain cerebral hemispheres in culture, J. Biol. Chem., 251 (1976) 1392-1397.