Direct interaction with and activation of p53 by SMAR1 retards cell-cycle progression at G2/M phase and delays tumor growth in mice

International Journal of Cancer

Volumn 103, Issue 5, 2003, Pages 606-615

  Kaul, Ruchika ^a   Mukherjee, Sujoy ^a   Ahmed, Farid ^a   Bhat, Manoj Kumar ^a   Chhipa, Rishiraj ^a   Galande, Sanjeev ^a   Chattopadhyay, Samit ^a  

^a NATIONAL CENTRE FOR CELL SCIENCE   (India)

Author keywords

G2 M arrest; Matrix attachment region; p21; p53; SMAR1

Indexed keywords

APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CELL DNA; CELL PROTEIN; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; MESSENGER RNA; PROTEIN BAX; PROTEIN MDM2; PROTEIN P21; PROTEIN P53;

ANIMAL CELL; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER INHIBITION; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CONTROLLED STUDY; EMBRYO; GENE ACTIVATION; GENE ACTIVITY; GENE EXPRESSION; GENE FUNCTION; GENE IDENTIFICATION; GENE INTERACTION; GENE OVEREXPRESSION; GENE TARGETING; GENETIC CODE; HUMAN; HUMAN CELL; IN VIVO STUDY; MELANOMA CELL; MITOSIS INHIBITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; SMAR1 GENE; TUMOR GROWTH; TUMOR SUPPRESSOR GENE;

ALTERNATIVE SPLICING; ANIMALS; BLOTTING, WESTERN; CELL CYCLE PROTEINS; CHLORAMPHENICOL O-ACETYLTRANSFERASE; DNA-BINDING PROTEINS; FLOW CYTOMETRY; G2 PHASE; HUMANS; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL; MITOSIS; NUCLEAR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, NEOPLASM; TRANSFECTION; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0037455822     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.10881     Document Type: Article

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