ERK signaling pathway is involved in p15INK4b/p16INK4a expression and HepG2 growth inhibition triggered by TPA and Saikosaponin a

Oncogene

Volumn 22, Issue 7, 2003, Pages 955-963

  Wu, Wen Sheng ^a  

^a TZU CHI UNIVERSITY   (Taiwan)

Author keywords

ERK; Growth inhibition; p15INK4b; p16INK4a

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; MITOGEN ACTIVATED PROTEIN KINASE; PHORBOL 13 ACETATE 12 MYRISTATE; PHORBOL ESTER; PROTEIN C FOS; PROTEIN C JUN; PROTEIN DERIVATIVE; PROTEIN P15; PROTEIN P16; RNA; SAIKOSAPONIN A; SYNAPTOPHYSIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR JUNB; UNCLASSIFIED DRUG;

ARTICLE; CAPILLARY ELECTROPHORESIS; CELL GROWTH; CELL LINE; CHINESE HERB; CONTROLLED STUDY; DNA BINDING; FLUORESCENCE ANALYSIS; GENE EXPRESSION; GROWTH INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTO ONCOGENE; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ACTIVATING TRANSCRIPTION FACTOR 2; CARCINOMA, HEPATOCELLULAR; CELL CYCLE PROTEINS; CELL DIVISION; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIN-DEPENDENT KINASE INHIBITOR P15; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DEPRESSION, CHEMICAL; ELECTROPHORESIS, CAPILLARY; ENZYME INDUCTION; ENZYME INHIBITORS; FLAVONOIDS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, FOS; GENES, JUN; GENES, P16; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIVER NEOPLASMS; MAP KINASE KINASE 1; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; NEOPLASM PROTEINS; OLEANOLIC ACID; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-FOS; PROTO-ONCOGENE PROTEINS C-JUN; SAPONINS; TETRADECANOYLPHORBOL ACETATE; TIME FACTORS; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEINS;

EID: 0037455723     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1206237     Document Type: Article

References (44)

1. Agadir A, Cen G-Q, Bost F, Li Y, Mercola D and Zhang X-K. (1999). J. Biol. Chem., 274(42), 29779-29785.
2. Bosch M, Gil J, Bachs O and Agell N (1998). J. Biol. Chem., 273, 22145-22150.
3. Campbell I, Magliocco A, Moyana T, Zheng C and Xiang J. (2000). Cancer Gene Ther 7(9), 1270-1278.
4. Cocolakis E, Lemay S, Ali S and Lebrun J-J. (2001). J. Biol. Chem., 276(21), 18430-18436.
5. Dam HV and Castellazzi M. (2001). Oncogene, 20, 2453-2464.
6. Derynck R, Akhurst RJ and Balmian A. (2001). Nat. Genet., 29, 117-129.
7. Faacchini LM and Penn LZ. (1998). FASEB J. 12, 633-651.
8. Fatima M-G, Damien G and Moshe Y. (2001). Oncogene, 20, 2378-2389.
9. Foulds GJ and Etzkorn FA. (1998). Nucleic Acid Res., 26(18), 4404-4305.
10. Franklin CC and Kraft AS. (1995). Oncogene, 11(11), 2365-2374.
11. Fuxe J, Akusjarvi G, Goike HM, Roos G, Collins VP and Pettersson RF. (2000). Cell growth Diff., 11(7), 373-384.
12. Gille H, Strahl T and Shaw PE. (1995). Curr. Biol., 5(10), 1191-1200.
13. Gold LI. (1999). Crit. Rev. Oncogen., 14(4), 303-360.
14. Halfter H, Friedrich M, Postert C, Ringelstein EB and Stogbauer F. (1999). Mol. Cell. Biol. Res. Commu., 1(2), 109-116.
15. Hartsough MT, Frey RS, Zipfel PA, Buard A, Cook SJ, McCromick F and Mulder KM. (1996). J. Biol. Chem., 271, 22368-22375.
16. Hochholdinger F, Baier G, Nogalo A, Bauer B, Grunicke HH and Uberall F. (1999). Mol. Cell. Biol., 19(12), 8042 8065.
17. Jin M, Piao Z, Kim NG, Park C, Shin EC, Park JM, Jung HJ, Kim CG and Kim H. (2000). Cancer, 89(1), 60-68.
18. Karin M. (1995). J. Biol. Chem., 270, 16483-16486.
19. Karin M, Liu Z and Zandi E. (1997). Curr. Opin Cell Biol., 9, 240-246.
20. Kavanagh KT, Hafer LJ, Kim DW, Mann KK, Sherr DH, Rogers AE and Sonenshein GE. (2001). J. Cell. Biochem., 82(3), 387-398.
21. Kimura A, Ohmichi M, Kurachi H, Ikegami H, Hayakawa J, Tasaka K, Kanda Y, Nishio Y, Jikihara H, Matsuura N and Murata Y. (1999). Cancer Res., 59(20), 5133-5142.
22. Latres E, Malumbres M, Sotillo R, Martin J, Ortega S, Martin- Caballero J, Flores JM, Cordon-Cardo C and Barbacid M. (2000). EMBO J., 19(13), 3496-3506.
23. Lin AW, Barradas M, Stone JC, Van Aelst L, Serrano M and Lowe SW. (1998). Genes Dev., 12, 3008-3019.
24. Lloyd AC. (1998). Curr. Opin. Genet Dev., 8, 43-48.
25. Malumbers M, Perez De Castro I, Hernaandez MI, Jimenez M, Corral T and Pellicer A. (2000). Mol. Cell. Biol., 20(8), 2915-2925.
26. Onishi T, Yamakawa K, Franco OE, Suzuki R and Kawamura J. (2000). Anticancer Res., 20(5A), 3075-3081.
27. Passegue E and Wagner EF. (2000). EMBO J., 19(12), 2969-2979.
28. Pumiglia KM and Decker SJ. (1997). Proc. Natl. Acad. Sci. USA, 94, 448-452.
29. Robson CN, Gnanapragasam V, Byrne RL, Collins AT and Neal DE. (1999). J. Endocrinol., 160, 257-266.
30. Roovers K and Assoian RK. (2000). BioEssays, 22, 818-826.
31. Roussel MF. (1999). Oncogene, 18(38), 5311-5317.
32. Seoane J, Pouponnot C, Staller P, Schader M, Eilers M and Massague J. (2001). Nat. Cell Biol., 3, 400-408.
33. Serrano M, Lee H-W, Chin L, Cordon-Cardo C, Beach D and Depinho RA. (1996). Cell, 85, 27-37.
34. Serrano M, Lin AW, McCurrach ME, Beach D and Lowe SW. (1997). Cell, 88, 593-602.
35. Shaulian E and Karian M. (2001). Oncogene, 20, 2390-2400.
36. Verlinden L, Verstuyf A, Van Camp M, Marcelis S, Sabbe K, Zhao XY, De Clercq P, Vandewalle M and Bouillon R. (2000). Cancer Res., 60(10), 2673-2679.
37. Wang Y and Prywes R. (2000). Oncogene, 19(11), 1379-1385.
38. Waskiewicz AJ and Cooper JA. (1995). Curr. Opin. Cell Biol., 7, 798-805.
39. Weber E, Ravi RK, Knudsen ES, William JR, Dillehay LE, Nelkin BD, Kalemkerian GP, Feremisco JR and Mabry M. (1999). Int. J. Cancer, 80(6), 935-943.
40. Wong H, Anderson WD, Cheng T and Riabowol KT. (1994). Anal. Biochem., 223(2), 251-258.
41. Woods D, Parry D, Cherwinski H, Lees E and McMahon M. (1997). Mol. Cell. Biol., 17, 5598-5611.
42. Wu W-S and Heu H-Y, (2001). Biochem. Biophys, Res. Commun., 285, 183-187.
43. Yang X, Chen Y and Gabuzda D. (1999). J. Biol Chem., 274(39), 27981-27988.
44. Zauberman K, Oren M and Zipori D. (1997). Oncogene, 15, 1705-1711.