Synthesis and evaluation of a novel series of farnesyl protein transferase inhibitors as non-peptidic CAAX tetrapeptide analogues

Bioorganic and Medicinal Chemistry Letters

Volumn 13, Issue 8, 2003, Pages 1455-1458

  Perez, Michel ^a   Maraval, Catherine ^a   Dumond, Stephan ^a   Lamothe, Marie ^a   Schambel, Philippe ^a   Etiévant, Chantal ^a   Hill, Bridget ^a  

^a INSTITUT DE RECHERCHE PIERRE FABRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; PIPERAZINE DERIVATIVE; PROTEIN FARNESYLTRANSFERASE; PROTEIN FARNESYLTRANSFERASE INHIBITOR;

ARTICLE; CELL ACTIVITY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SCREENING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; ENZYME ISOLATION; HUMAN; HUMAN CELL; IC 50; PROTEIN DETERMINATION; STRUCTURE ANALYSIS;

EID: 0037451822     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(03)00170-7     Document Type: Article

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