Inhibition of dipeptidyl peptidase IV (DPP IV) by 2-(2-amino-1-fluoro-propylidene)-cyclopentanecarbonitrile, a fluoroolefin containing peptidomimetic

Bioorganic and Medicinal Chemistry

Volumn 11, Issue 2, 2003, Pages 207-215

  Zhao, Kake ^a   Lim, Dong Sung ^a   Funaki, Takashi ^a   Welch, John T ^a  

^a STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 1 FLUOROPROPYLIDENE)CYCLOPENTANECARBONITRILE; DIPEPTIDYL PEPTIDASE IV; ENZYME INHIBITOR; UNCLASSIFIED DRUG; BIOMIMETIC MATERIAL; NITRILE; PEPTIDE; PROTEINASE INHIBITOR;

ARTICLE; CHEMICAL REACTION; DRUG DEGRADATION; ENZYME INHIBITION; PETERSON FLUOROOLEFINATION; PH; BINDING COMPETITION; CHEMISTRY; COMPARATIVE STUDY; DRUG STABILITY; ENZYMOLOGY; FEMALE; HUMAN; METABOLISM; PLACENTA; PREGNANCY; STEREOISOMERISM; SYNTHESIS;

ANTIGENS, CD26; BINDING, COMPETITIVE; BIOMIMETIC MATERIALS; DRUG STABILITY; FEMALE; HUMANS; HYDROGEN-ION CONCENTRATION; NITRILES; PEPTIDES; PLACENTA; PREGNANCY; PROTEASE INHIBITORS; STEREOISOMERISM;

EID: 0037449356     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(02)00384-X     Document Type: Article

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