Dipeptidyl peptidase IV from human serum: Purification, characterization, and N-terminal amino acid sequence

Journal of Biochemistry

Volumn 124, Issue 2, 1998, Pages 428-433

  Iwaki Egawa, Sachiko ^a   Watanabe, Yasuhiro ^a   Kikuya, Yasuoki ^a   Fujimoto, Yukio ^a  

^a HOKKAIDO INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

Adenosine deaminase; Dipeptidyl peptidase IV; Human serum; Kidney; N terminal amino acid sequence

Indexed keywords

ADENOSINE DEAMINASE; ANTIBODY; COMPLEMENTARY DNA; DIPEPTIDYL PEPTIDASE IV; MEMBRANE ENZYME; SERINE;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; ENZYME BLOOD LEVEL; ENZYME INHIBITION; ENZYME PURIFICATION; ENZYME SPECIFICITY; HUMAN; HUMAN TISSUE; KIDNEY; NUCLEOTIDE SEQUENCE; POLYACRYLAMIDE GEL ELECTROPHORESIS;

EID: 0031657655     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a022130     Document Type: Article

References (43)

1. Wu, Q., Lahti, J.M., Air, G.M., Burrows, P.D., and Cooper, M.D. (1990) Molecular cloning of the murine BP-1/6C3 antigen: A member of the zinc-dependent metallopeptidase family. Proc. Natl. Acad. Sci. USA 87, 993-997
2. Nanus, D.M., Engelstein, D., Gastl, G.A., Gluck, L., Vidal, M.J., Morrison, M., Finstad, C.L., Bander, N.H., and Albino, A.P. (1993) Molecular cloning of the human kidney differentiation antigen gp160: Human aminopeptidase A. Proc. Natl. Acad. Sci. USA 90, 7069-7073
3. Rogi, T., Tsujimoto, M., Nakazato, H., Mizutani, S., and Tomoda, Y. (1996) Human placental leucine aminopeptidase/oxytocinase: A new member of type II membrane-spanning zinc metallopeptidase family. J. Biol. Chem. 271, 56-61
4. Laustsen, P.G., Rasmussen, T.E., Petersen, K., Pedraza-Diaz, S., Moestrup, S.K., Gliemann, J., Sottrup-Jensen, L., and Kristensen, T. (1997) The complete amino acid sequence of human placental oxytocinase. Biochim. Biophys. Acta 1352, 1-7
5. Shipp, M.A., Richardson, N.E., Sayre, P.H., Brown, N.R., Masteller, E.L., Clayton, L.K., Ritz, J., and Reinherz, E.L. (1988) Molecular cloning of the common acute lymphoblastic leukemia antigen (CALLA) identifies a type II integral membrane protein. Proc. Natl. Acad. Sci. USA 85, 4819-4823
6. Look, A.T., Ashmun, R.A., Shapiro, L.H., and Peiper, S.C. (1989) Human myeloid plasma membrane glycoprotein CD13 (gp150) is identical to aminopeptidase N. J. Clin. Invest. 83, 1299-1307
7. 2-terminal signal sequence as the membrane-anchoring domain. J. Biol. Chem. 264, 3596-3601
8. Misumi, Y., Hayashi, Y., Arakawa, F., and Ikehara, Y. (1992) Molecular cloning and sequence analysis of human dipeptidyl peptidase-IV, a serine proteinase on the cell surface. Biochim. Biophys. Acta 1131, 333-336
9. Tanaka, T., Camerini, D., Seed, B., Torimoto, Y., Dang, N.H., Kameoka, J., Dahlberg, H.N., Schlossman, S.F., and Morimoto, C. (1992) Cloning and functional expression of the T-cell activation antigen CD26. J. Immunol. 149, 481-486
10. Shipp, M.A. and Look, A.T. (1993) Hematopoietic differentiation antigens that are membrane-associated enzymes: Cutting is the key. Blood 82, 1052-1070
11. Hopsu-Havu, V.K. and Glenner, G.G. (1966) A new dipeptide naphthylamidase hydrolyzing glycyl-prolyl-β-naphthylamide. Histochemie 7, 197-201
12. Walter, R., Simmons, W.H., and Yoshimoto, T. (1980) Proline specific endo-and exopeptidases. Mol. Cell. Biochem. 30, 111-127
13. Tiruppathi, C., Miyamoto, Y., Ganapathy, V., Roesel, R.A., Whitford, G.M., and Leibach, F.H. (1990) Hydrolysis and transport of proline-containing peptides in renal brush-border membrane vesicles from dipeptidyl peptidase IV-positive and dipeptidyl peptidase IV-negative rat strains. J. Biol. Chem. 265, 1476-1483
14. Barton, R.W., Prendergast, J., and Kennedy, C.A. (1990) Binding of the T cell activation monoclonal antibody Ta1 to dipeptidyl peptidase IV. J. Leukocyte Biol. 48, 291-296
15. Torimoto, Y., Dang, N.H., Tanaka, T., Prado, C., Schlossman, S.F., and Morimoto, C. (1992) Biochemical characterization of CD26 (dipeptidyl peptidase IV): functional comparison of distinct epitopes recognized by various anti-CD26 monoclonal antibodies. Mol. Immunol. 29, 183-192
16. Schön, E., Jahn, S., Kiessig, S.T., Demuth, H.-U., Neubert, K., Barth, A., Von Baehr, R., and Ansorge, S. (1987) The role of dipeptidyl peptidase IV in human T lymphocyte activation. Inhibitors and antibodies against dipeptidyl peptidase IV suppress lymphocyte proliferation and immunoglobulin synthesis in vitro. Eur. J. Immunol. 17, 1821-1826
17. Dang, N.H., Torimoto, Y., Deusch, K., Schlossman, S.F., and Morimoto, C. (1990) Comitogenic effect of solid-phase immobilized anti-1F7 on human CD4 T cell activation via CD3 and CD2 pathways. J. Immunol. 144, 4092-4100
18. Bednarczyk, J.L., Carroll, S.M., Marin, C., and Mclntyre, B.W. (1991) Triggering of the proteinase dipeptidyl peptidase IV (CD26) amplifies human T lymphocyte proliferation. J. Cell. Biochem. 46, 206-218
19. Oravecz, T., Roderiquez, G., Koffi, J., Wang, J.H., Ditto, M., Bouhabib, D.C., Lusso, P., and Norcross, M.A. (1995) CD26 expression correlates with entry, replication and cytopathicity of monocytotropic HIV-1 strains in a T-cell line. Nat. Med. 1, 919-926
20. Oravecz, T., Pall, M., Roderiquez, G., Gorrell, M.D., Ditto, M., Nguyen, N.Y., Boykins, R., Unsworth, E., and Norcross, M.A. (1997) Regulation of the receptor specificity and function of the chemokine RANTES (regulated on activation, normal T cell expressed and secreted) by dipeptidyl peptidase IV (CD26)-mediated cleavage. J. Exp. Med. 186, 1865-1872
21. Morrison, M.E., Vijayasaradhi, S., Engelstein, D., Albino, A.P., and Houghton, A.N. (1993) A marker for neoplastic progression of human melanocytes is a cell surface ectopeptidase. J. Exp. Med. 177, 1135-1143
22. DeMeester, I., Vanham, G., Kestens, L., Vanhoof, G., Bosmans, E., Gigase, P., and Scharpé, S. (1994) Binding of adenosine deaminase to the lymphocyte surface via CD26. Eur. J. Immunol. 24, 566-570
23. Giblett, E.R., Anderson, J.E., Cohen, F., Pollara, B., and Meuwissen, H.J. (1972) Adenosine-deaminase deficiency in two patients with severely impaired cellular immunity. Lancet 2, 1067-1069
24. Maes, M., Scharpe, S., De Meester, I., Goossens, P., Wauters, A., Neels, H., Verkerk, R., Demeyer, F., Dhondt, P., Peeters, D., Schotte, C., and Cosyns, P. (1994) Components of biological variation in prolyl endopeptidase and dipeptidylpeptidase IV activity in plasma of healthy subjects. Clin. Chem. 40, 1686-1691
25. Ohkubo, I., Huang, K., Ochiai, Y., Takagaki, M., and Kani, K. (1994) Dipeptidyl peptidase IV from porcine seminal plasma: Purification, characterization, and N-terminal amino acid sequence. J. Biochem. 116, 1182-1186
26. Kojima, J., Kanatani, M., Kato, M., Tojoh, F., and Nakamura, N. (1979) Serum glycylproline dipeptidyl aminopeptidase activity in human hepatic cancer. Clin. Chim. Acta 93, 181-187
27. Hino, M., Nagatsu, T., Kakumu, S., Okuyama, S., Yoshii, Y., and Nagatsu, I. (1975) Glycylprolyl β-naphthylamidase activity in human serum. Clin. Chim. Acta 62, 5-11
28. Fujita, K., Hirano, M., Ochiai, J., Funabashi, M., Nagatsu, I., Nagatsu, T., and Sakakibara, S. (1978) Serum glycylproline ρ-nitroanilidase activity in rheumatoid arthritis and systemic lupus erythematosus. Clin. Chim. Acta 88, 15-20
29. Iwaki-Egawa, S., Watanabe, Y., and Fujimoto, Y. (1995) Is CD26/dipeptidyl peptidase IV a really important molecule on T-cell activation in a certain strain rat? Immunobiology 194, 429-442
30. Laemmli, U.K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685
31. Fahey, J.L. and Terry, E.W. (1973) in Handbook of Experimental Immunology (Weir, D.M., eds.) Vol. 1, Chapter 7, Blackwell Scientific Publications, Oxford
32. Watanabe, Y., Kojima, T., and Fujimoto, Y. (1987) Deficiency of membrane-bound dipeptidyl aminopeptidase IV in a certain rat strain. Experientia 43, 400-401
33. Iwaki-Egawa, S., Watanabe, Y., and Fujimoto, Y. (1997) CD26/ Dipeptidyl peptidase IV does not work as an adenosine deaminase-binding protein in rat cells. Cell. Immunol. 178, 180-186
34. Iwaki-Egawa, S., Watanabe, Y., and Fujimoto, Y. (1993) N-Terminal amino acid sequence of the 60 kDa protein of rat kidney dipeptidyl peptidase IV. Biol. Chem. Hoppe-Seyler 374, 973-975
35. 2 from bradykinin, by X-Pro dipeptidyl-aminopeptidase. Biochim. Biophys. Acta 525, 417-422
36. Umezawa, H., Aoyagi, T., Ogawa, K., Naganawa, H., Hamada, M., and Takeuchi, T. (1984) Diprotins A and B, inhibitors of dipeptidyl aminopeptidase IV, produced by bacteria. J. Antibiot. 37, 422-425
37. Watanabe, Y., Iwaki-Egawa, S., Mizukoshi, H., and Fujimoto, Y. (1995) Identification of an alanine aminopeptidase in human maternal serum as a membrane-bound aminopeptidase N. Biol. Chem. Hoppe-Seyler 376, 397-400
38. Watanabe, Y., Iwaki-Egawa, S., Yokosawa, J., Mizukoshi, H., and Fujimoto, Y. (1996) An antibody specific to N-terminal amino acid sequence of human maternal serum cystine amino-peptidase and its applications. Biochem. Mol. Biol. Int. 38, 653-658
39. Watanabe, Y., Ito, K., Iwaki-Egawa, S., Yamaguchi, R., and Fujimoto, Y. (1998) Aminopeptidase N in sera of healthy subjects is a different N-terminal processed derivative from the one obtained from maternal serum. Mol.. Genet. Metab. 63, 289-294
40. Duke-Cohan, J.S., Morimoto, C., Rocker, J.A., and Schlossman, S.F. (1995) A novel form of dipeptidylpeptidase IV found in human serum: Isolation, characterization, and comparison with T lymphocyte membrane dipeptidylpeptidase IV (CD26). J. Biol. Chem. 270, 14107-14114
41. Duke-Cohan, J.S., Morimoto, C., Rocker, J.A., and Schlossman, S.F. (1996) Serum high molecular weight dipeptidyl peptidase IV (CD26) is similar to a novel antigen DPPT-L released from activated T cells. J. Immunol. 156, 1714-1721
42. Van der Weyden, M.B. and Kelley, W.N. (1976) Human adenosine deaminase distribution and properties. J. Biol. Chem. 251, 5448-5456
43. Kameoka, J., Tanaka, T., Nojima, Y., Schlossman, S.F., and Morimoto, C. (1993) Direct association of adenosine deaminase with a T-cell activation antigen, CD26. Science 261, 466-469