Signal transduction events induced or affected by inhibition of the catalytic activity of dipeptidyl peptidase IV (DP IV, CD26)

Advances in Experimental Medicine and Biology

Volumn 477, Issue , 2000, Pages 131-137

  Kaähne, Thilo ^a   Reinhold, Dirk ^a   Neubert, Klaus ^b   Born, Ilona ^b   Faust, Jürgen ^b   Ansorge, Siegfried ^a  

^a OTTO VON GUERICKE UNIVERSITY   (Germany)

^b MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

CD26; Dipeptidyl peptidase IV; Inhibitors; Signal transduction

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR; CYTOKINE; DIPEPTIDYL PEPTIDASE IV; DIPEPTIDYL PEPTIDASE IV INHIBITOR; DNA; ENZYME INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN P27; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

CALCIUM MOBILIZATION; CONFERENCE PAPER; CONTROLLED STUDY; DNA SYNTHESIS INHIBITION; ENZYME INHIBITION; HUMAN; HUMAN CELL; IMMUNOREGULATION; LYMPHOCYTE PROLIFERATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

ANTIGENS, CD26; CALCIUM SIGNALING; CATALYSIS; CELL CYCLE PROTEINS; CYCLIN-DEPENDENT KINASE INHIBITOR P27; ENZYME ACTIVATION; G1 PHASE; HUMANS; HYDROLYSIS; LYMPHOCYTE ACTIVATION; MAP KINASE SIGNALING SYSTEM; MICROTUBULE-ASSOCIATED PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASES; MUROMONAB-CD3; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; SERINE PROTEINASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP; T-LYMPHOCYTES; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; TUMOR SUPPRESSOR PROTEINS;

EID: 0034470249     PISSN: 00652598     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

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5. Cross-linking of CD26 by antibody induces tyrosine phosphorylation and activation of mitogen-activated protein kinase
6. A new peptide naphtylamidase hydrolyzing glycylprolyl-naphtylamide
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10. p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest
11. Inhibitors of dipeptidyl peptidase IV (DPIV, CD26) specifically suppress proliferation and modulate cytokine production of strongly CD26 expressing U937 cells
12. Inhibitors of dipeptidyl peptidase IV (DP IV, CD26) induces secretion of transforming growth factor-beta 1 (TGF-beta 1) in stimulated mouse splenocytes and thymocytes
13. The dipeptidyl peptidase IV, a membrane enzyme involved in the proliferation of T lymphocytes
14. Dipeptidyl-peptidase IV/CD26 on T cells: Analysis of an alternative T- cell activation pathway