Newly designed hydrogel with both sensitive thermoresponse and biodegradability

Journal of Polymer Science, Part A: Polymer Chemistry

Volumn 41, Issue 6, 2003, Pages 779-787

  Yoshida, Takatsune ^a   Aoyagi, Takao ^b   Kokufuta, Etsuo ^a   Okano, Teruo ^b  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

Author keywords

Biodegradable; Crosslinking; Drug delivery systems; Hydrogel; Hydrogels; Poly(amino acids); Poly(N isopropylacrylamide); Thermoresponsive polymer

Indexed keywords

BIODEGRADATION; CARBOXYLATION; CHARACTERIZATION; COPOLYMERS; CROSSLINKING; DRUG PRODUCTS; ESTERS; MONOMERS; POLYMERIZATION; SOLUTIONS; SWELLING; SYNTHESIS (CHEMICAL);

AMINO ACID CARBOXYANHYDRIDES; BIODEGRADABILITY; DECARBOXYLATION POLYMERIZATION; ISOPROPYLACRYLAMIDE COPOLYMERS; POLYAMINO ACIDS; THERMORESPONSIVE HYDROGELS;

HYDROGELS;

COPOLYMER; POLY(N ISOPROPYLACRYLAMIDE); POLYAMINOACID;

HYDROGEL;

AQUEOUS SOLUTION; CROSS LINKING; DECARBOXYLATION; DRUG DELIVERY SYSTEM; HYDROGEL;

EID: 0037445485     PISSN: 0887624X     EISSN: None     Source Type: Journal    
DOI: 10.1002/pola.10595     Document Type: Article

References (23)

1. Bromberg, L. E.; Ron, E. S. Adv Drug Delivery Rev 1998, 3, 197-221.
2. Kikuchi, A.; Okano, T. Adv Drug Delivery Rev 2002, 3, 53-77.
3. Mooney, D. J.; Mikos, A. G. Sci Am Apr 1999, 60-65.
4. Okano, T.; Bae, Y. H.; Kim, J. H.; Kim, S. W. J Controlled Release 1990, 11, 255-265.
5. Yoshida, R.; Sakai, K.; Okano, T.; Sakurai, Y.; Bae, Y. H.; Kim, S. W. J Biomater Sci Polym Ed 1991, 3, 155-162.
6. Ulbrich, K.; Strohalm, J.; Kopecek, J. Biomaterials 1982, 3, 150-154.
7. Subr, V.; Duncan, R.; Kopecek, J. J Biomater Sci Polym Ed 1990, 1, 261-278.
8. Jeong, B.; Bae, Y. H.; Lee, D. S.; Kim, S. W. Nature 1997, 388, 860-862.
9. Jeong, B.; Choi, Y. K.; Bae, Y. H.; Zentner, G.; Kim, S. W. J Controlled Release 1999, 62, 109-114.
10. Kurisawa, M.; Matsuo, Y.; Yui, N. Macromol Chem Phys 1998, 199, 705-709.
11. Feil, H.; Bae, Y. H.; Feijan, J.; Kim, S. W. Macromolecules 1993, 26, 2496-2500.
12. Aoyagi, T.; Ebara, M.; Sakai, K.; Sakurai, Y.; Okano, T. J Biomater Sci Polym Ed 2000, 11, 101-110.
13. Ebara, M.; Aoyagi, T.; Sakai, K.; Okano, T. Macromolecules 2000, 33, 8312-8316.
14. Ebara, M.; Aoyagi, T.; Sakai, K.; Okano, T. J Polym Sci Part A: Polym Chem 2001, 39, 335-342.
15. Daly, W. H.; Poche, D. Tetrahedron Lett 1988, 29, 5859-5862.
16. Eckert, H.; Forster, B. Angew Chem Int Ed Engl 1987, 26, 894-895.
17. Yokoyama, M.; Fukushima, S.; Uehara, R.; Okamoto, K.; Kataoka, K.; Sakurai, Y.; Okano, T. J Controlled Release 1998, 50, 79-92.
18. Harada, A.; Kataoka, K. Macromolecules 1998, 31, 288-294.
19. Nishiyama, N.; Yokoyama, M.; Aoyagi, T.; Okano, T.; Sakurai, Y.; Kataoka, K. Langmuir 1999, 15, 377-383
20. Aoyagi, T.; Sugi, K.; Sakurai, Y.; Okano, T.; Kataoka, K. Colloids Surf B 1999, 16, 237-242.
21. Kataoka, K.; Matsumoto, T.; Yokoyama, M.; Okano, T.; Sakurai, Y.; Fukushima, S.; Okamoto, K.; Kwon, G. S. J Controlled Release 2000, 64, 143-153.
22. Nishiyama, N.; Kataoka, K. J Controlled Release 2001, 74, 83-94.
23. Yui, N.; Okano, T.; Sakurai, Y. J Controlled Release 1993, 26, 141-145.