Down-regulation of T helper 1 responses to mycobacterial antigens due to maturation of dendritic cells by 10-kDa Mycobacterium tuberculosis secretory antigen

Journal of Infectious Diseases

Volumn 187, Issue 6, 2003, Pages 914-928

  Natarajan, Krishnamurthy ^a   Latchumanan, Vinoth K ^a   Singh, Balwan ^a   Singh, Sarman ^b   Sharma, Pawan ^a  

^a INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY ICGEB   (India)

^b ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CELL EXTRACT; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 2; MYCOBACTERIUM ANTIGEN; SECRETORY ANTIGEN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIGEN PRESENTING CELL; ARTICLE; BACTERIUM CULTURE; CELL MATURATION; COCULTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; DOWN REGULATION; FEMALE; IMMUNE RESPONSE; INFLAMMATION; MACROPHAGE; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; TH1 CELL; TUBERCULOSIS;

ANIMALS; BACTERIAL PROTEINS; CELL DIFFERENTIATION; COCULTURE TECHNIQUES; DENDRITIC CELLS; DOWN-REGULATION; FEMALE; HUMANS; INTERFERON TYPE II; INTERLEUKIN-2; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MYCOBACTERIUM TUBERCULOSIS; TH1 CELLS;

EID: 0037443932     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/368173     Document Type: Article

References (66)

1. World Health Organization. Global tuberculosis control. World Health Organization. Geneva: 1998.
2. Dolin PJ, Raviglione MC, Kochi A. Global tuberculosis incidence and mortality during 1990-2000. Bull World Health Organ 1994; 72:213-20.
3. Bloom BR, Murray CJL. Tuberculosis: commentary on a re-emergent killer. Science 1992; 257:1055-64.
4. Colditz GA, Brewer FT, Berkey CS, et al. Efficacy of BCG vaccine in the prevention of tuberculosis: meta-analyses of the published literature. JAMA 1994; 271:698-702.
5. Kaufmann SHE. Is the development of a new tuberculosis vaccine possible? Nat Med 2000; 6:955-60.
6. Fine PE. Variation in protection by BCG: implications of and for heterologous immunity. Lancet 1995; 346:1339-45.
7. Hess JH, Schaible UE, Raupach B, Kaufmann SHE. Exploiting the immune system: toward new vaccines against intracellular bacteria. Adv Immunol 2000; 75:1-8.
8. Manabe YC, Bishai WR. Latent Mycobacterium tuberculosis: persistence, patience, and winning by waiting. Nat Med 2000; 6:1327-9.
9. Foote S. Mediating immunity to mycobacteria. Nat Genet 1999; 21:345-6.
10. Flynn JA, Chan J. Immnuology of tuberculosis. Annu Rev Immunol 2001; 19:93-129.
11. Beatty WL, Russel DG. Identification of mycobacterial surface proteins released into subcellular compartments of infected macrophages. Infect Immun 2000; 68:6997-7002.
12. Anderson P. Effective vaccination of mice against Mycobacterium tuberculosis infection with a soluble mixture of secreted mycobacterial proteins. Infect Immun 1994; 62:2536-44.
13. Roberts AD, Sonnenberg MG, Ordway DJ, et al. Characteristics of protective immunity engendered by vaccination of mice with purified culture filtrate protein antigens of Mycobacterium tuberculosis. Immunology 1995; 85:502-8.
14. Roche PW, Triccas JA, Avery DT, Fifts T, Billman-Jacobe H, Britton WJ. Differential T cell responses to mycobacteria-secreted proteins distinguish vaccination with bacille Calmette Guérin from infection with Mycobacterium tuberculosis. J Infect Dis 1994; 170:1326-30.
15. Anderson PA, Anderson P, Sorenson L, Nagai S. Recall of long-lived immunity to Mycobacterium tuberculosis infection in mice. J Immunol 1995; 154:3359-72.
16. Banchereau J, Steinman RM. Dendritic cells and the control of immunity. Nature 1998; 392:245-52.
17. Steinman RM. Dendritic cells. In: Paul WE, ed. Fundamental immunology. Philadelphia: Lippincott-Raven, 1999:547-73.
18. Reid SD, Penna G, Adorini, L. The control of T cell responses by dendritic cells subsets. Curr Opin Immunol 2000; 12:114-21.
19. Sousa CR. Dendritic cells as sensors of infection. Immunity 2001; 14:495-8.
20. Colangeli R, Spencer JS, Bifani P, et al. MTSA-10, the product of the Rv3874 gene of Mycobacterium tuberculosis, elicits tuberculosis-specific, delayed-type hypersensitivity in guinea pigs. Infect Immun 2000; 68:990-3.
21. Dillon DC, Alderson MR, Day CH, et al. Molecular and immunological characterization of Mycobacterium tuberculosis CFP-10, an immunodiagnostic antigen missing in Mycobacterium bovis BCG. J Clin Microbiol 2000; 38:3285-90.
22. + T lymphocytes derived from Mycobacterium tuberculosis-infected cells: definition of antigenic specificity. J Immunol 2001; 166:439-46.
23. Arend SM, Ottenhoff TH, Andersen P, van Dissel JT. Uncommon presentations of tuberculosis: the potential value of a novel diagnostic assay based on the Mycobacterium tuberculosis-specific antigens ESAT-6 and CFP-10. Int J Tuberc Lung Dis 2001; 5:680-6.
24. Brock I, Munk ME, Kok-Jensen A, Andersen R. Performance of whole blood IFN-gamma test for tuberculosis diagnosis based on PPD or the specific antigens ESAT-6 and CFP-10. Int J Tuberc Lung Dis 2001; 5:462-7.
25. Trajkovic V, Singh G, Singh B, Singh S, Sharma P. Effect of Mycobacterium tuberculosis-specific 10-kilodalton antigen on macrophage release of tumor necrosis factor alpha and nitric oxide. Infect Immun 2002; 70:6558-66.
26. Latchumanan VK, Singh B, Sharma P, Natarajan K. Mycobacterium tuberculosis antigens induce the differentiation of dendritic cells from bone marrow. J Immunol 2002; 169:6856-64.
27. Natarajan K, Sahoo NC, Rao KVS. Signal thresholds and modular synergy during expression of costimulatory molecules in B lymphocytes. J Immunol 2001; 167:114-22.
28. Vijayakrishnan L, Natarajan K, Manivel V, Raisuddin S, Rao KV. B cell responses to a peptide epitope. IX. The kinetics of antigen binding differentially regulates the costimulatory capacity of activated B cells. J Immunol 2000; 164:5605-14.
29. Inaba K, Inaba M, Romani M, et al. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J Exp Med 1992; 176:1693-702.
30. Scheicher C, Mehlig M, Zecher R, Reske K. Dendritic cells from mouse bone marrow: in vitro differentiation using low doses of recombinant granulocyte/macrophage colony-stimulating factor. J Immunol Methods 1992; 154:253-64.
31. Gonzalez-Juarrero M, Orme IR. Characterization of murine lung dendritic cells infected with Mycobacterium tuberculosis. Infect Immun 2001; 69:1127-31.
32. Jeannin P, Renno T, Goetsch L, et al. OmpA targets dendritic cells, induces their maturation and delivers antigen into the MHC class I presentation pathway. Nat Immunol 2000; 1:502-9.
33. Takeuchi O, Kawai T, Mulradt PF, et al. Discrimination of bacterial lipoproteins by Toll-like receptor 6. Int Immunol 2001; 13:933-40.
34. - subclasses of dendritic cells direct the development of distinct T helper cells in vivo. J Exp Med 1999; 189:587-92.
35. Souji R, Matsumoto M, Tekeuchi O, et al. Maturation of human dendritic cells by cell wall skeleton of Mycobacterium bovis bacillus Calmette-Guerin: involvement of toll-like receptors. Infect Immun 2000; 68:6883-90.
36. Henderson RA, Watkins SC, Flynn JA. Activation of human dendritic cells following infection with Mycobacterium tuberculosis. J Immunol 1997; 159:635-43.
37. Bodnar KA, Serbina NV, Flynn JL. Fate of Mycobacterium tuberculosis within murine dendritic cells. Infect Immun 2001; 69:800-9.
38. Demangel C, Palendira U, Feng CG, Heath AW, Bean AG, Britton WJ. Stimulation of dendritic cells via CD40 enhances immune responses to Mycobacterium tuberculosis infection. Infect Immun 2001; 69:2456-61.
39. Demangel C, Bean AG, Martin E, Feng CG, Kamath AT, Britton WJ. Protection against aerosol Mycobacterium tuberculosis infection using Mycobacterium bovis bacillus Calmette Guérin-infected dendritic cells. Eur J Immunol 1999; 29:1972-9.
40. Hertz CJ, Kiertscher SM, Godowski PJ, et al. Microbial lipopeptides stimulate dendritic cell maturation via Toll-like receptor 2. J Immunol 2001; 166:2444-50.
41. Brandt L, Oettinger T, Holm A, Andersen P. Key epitopes on the ESAT-6 antigen recognized by mice during the recall of protective immunity to Mycobacterium tuberculosis. J Immunol 1996; 157:3527-33.
42. Elhay MJ, Oettinger T, Andersen P. Delayed type hypersensitivity response to ESAT-6 and MPT64 from Mycobacterium tuberculosis in the guinea pig. Infect Immun 1998; 66:3454-6.
43. Oettinger T, Andersen AB. Cloning and B-cell-epitope mapping of MPT64 from Mycobacterium tuberculosis H37Rv. Infect Immun 1994; 62:2058-64.
44. Harboe M, Oettinger T, Wiker HG, Rosenkrands I, Andersen P. Evidence for occurrence of the ESAT-6 protein in Mycobacterium tuberculosis and virulent Mycobactrium bovis and its absence in Mycobacterium bovis BCG. Infect Immun 1996; 64:16-22.
45. Sorensen AL, Nagai S, Houen G, Andersen P, Andersen AB. Purification and characterization of a low-molecular-mass T-cell antigen secreted by Mycobacterium tuberculosis. Infect Immun 1995; 63:1710-7.
46. Haga S, Yamaguchi R, Nagai S, Matsuo K, Yamazaki A, Nakamura RM. Delayed-type hypersensitivity to a recombinant mycobacterial antigen MPT64 in guinea pigs sensitized by Mycobacterium tuberculosis or Mycobacterium bovis BCG. J Leukoc Biol 1995; 57:221-5.
47. Roche PW, Winter N, Triccas JA, Feng CG, Britton WJ. Expression of Mycobacterium tuberculosis MPT64 in recombinant Mycobacterium smegmatis: purification, immunogeneticity and application to skin tests for tuberculosis. Clin Exp Immunol 1996; 103:226-32.
48. Brandt L, Elhay M, Rosenkrands I, Lindblad EB, Andersen P. ESAT-6 subunit vaccination against Mycobacterium tuberculosis. Infect Immun 2000; 68:791-5.
49. Ratliff TL, McGarr JA, Abou-Zeid C, et al. Attachment of mycobacteria to fibronectin-coated surfaces. J Gen Microbiol 1988; 134:1307-13.
50. Tanghe A, D'Souza S, Rossesls V, et al. Improved immunogenicity and protective efficacy of a tuberculosis DNA vaccine encoding Ag85 by protein boosting. Infect Immun 2001; 69:3041-7.
51. Kamath AT, Briscoe H, Britton WJ. Co-immunization with DNA vaccines expressing granulocyte-macrophage colony-stimulating factor and mycobacterial secreted proteins enhances T-cell immunity, but not protective efficacy against Mycobacterium tuberculosis. Immunology 1999; 96:511-6.
52. Pieters J. Entry and survival of pathogenic mycobacteria in macrophages. Microbes Infect 2001; 3:249-55.
53. + cells in vivo. J Immunol 2000; 165:6029-35.
54. Gursel M, Verthelyi D, Klinman DM. CpG oligodeoxynucleotides induce human monocytes to mature into functional dendritic cells. Eur J Immunol 2002; 32:2617-22.
55. Giacomini E, Iona E, Ferroni L, et al. Infection of human macrophages and dendritic cells with Mycobacterium tuberculosis induces a differential cytokine gene expression that modulates T cell response. J Immunol 2001; 166:7033-41.
56. Remoli ME, Giacomini E, Lutfalla G, et al. Selective expression of type I IFN genes in human dendritic cells infected with Mycobacterium tuberculosis. J Immunol 2002; 169:366-74.
57. Hickman SP, Chan J, Salgame P. Mycobacterium tuberculosis induces differential cytokine production from dendritic cells and macrophages with divergent effects on naive T cell polarization. J Immunol 2002; 168:4636-42.
58. Fortsch D, Rollinghoff M, Stenger S. IL-10 converts human dendritic cells into macrophage-like cells with increased antibacterial activity against virulent Mycobacterium tuberculosis. J Immunol 2000; 165:978-87.
59. Kournilsky P, Truffa-bachi P. Cytokine fields and the polarization of the immune response. Trends Immunol 2001; 22:502-9.
60. Kalinski P, Hilkens CM, Weirnenga EA, Kapsenberg ML. T-cell priming by type-1 and type-2 polarized dendritic cells: the concept of the third signal. Immunol Today 1999; 20:561-7.
61. Giacomini E, Iona E, Ferroni L, et al. Infection of human macrophages and dendritic cells with Mycobacterium tuberculosis induces a differential cytokine gene expression that modulates T cell response. J Immunol 2001; 166:7033-41.
62. + T cells in lungs following aerosol infection with Mycobacterium tuberculosis. Infect Immun 1999; 67:3242-7.
63. Pulendran B, Smith JL, Caspary G, et al. Distinct dendritic cell subsets differentially regulate the class of immune response in vivo. Proc Natl Acad Sci USA 1999; 96:1036-41.
64. + T cells with specificity for a novel mycobacterial epitope. Int Immunol 2001; 13:451-8.
65. Sousa AO, Mazzaccaro RJ, Russell RG, et al. Relative contributions of distinct MHC class I-dependent cell populations in protection to tuberculosis infection in mice. Proc Natl Acad Sci USA 2000; 97:4204-8.
66. Proudfoot AE, Power CA, Wells TN. The strategy of blocking the chemokine system to combat disease. Immunol Rev 2000; 177:246-56.