메뉴 건너뛰기




Volumn 21, Issue 4, 2003, Pages 740-753

Hereditary breast-ovarian cancer at the bedside: Role of the medical oncologist

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN;

EID: 0037441808     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2003.05.096     Document Type: Review
Times cited : (44)

References (87)
  • 2
    • 0036247145 scopus 로고    scopus 로고
    • Genes other than BRCA1 and BRCA2 involved in breast cancer susceptibility
    • de Jong MM, Nolte IM, te Meerman GJ, et al: Genes other than BRCA1 and BRCA2 involved in breast cancer susceptibility. J Med Genet 39:225-242, 2002
    • (2002) J Med Genet , vol.39 , pp. 225-242
    • de Jong, M.M.1    Nolte, I.M.2    te Meerman, G.J.3
  • 3
    • 0028202555 scopus 로고
    • Hereditary breast cancer and family cancer syndromes
    • Lynch HT, Lynch J, Conway T, et al: Hereditary breast cancer and family cancer syndromes. World J Surg 18:21-31, 1994
    • (1994) World J Surg , vol.18 , pp. 21-31
    • Lynch, H.T.1    Lynch, J.2    Conway, T.3
  • 4
    • 0015524144 scopus 로고
    • Tumor variation in families with breast cancer
    • Lynch HT, Krush AJ, Lemon HM, et al: Tumor variation in families with breast cancer. J Am Med Assoc 222:1631-1635, 1972
    • (1972) J Am Med Assoc , vol.222 , pp. 1631-1635
    • Lynch, H.T.1    Krush, A.J.2    Lemon, H.M.3
  • 5
    • 0015143062 scopus 로고
    • Carcinoma of the breast and ovary in three families
    • Lynch HT, Krush AJ: Carcinoma of the breast and ovary in three families. Surg Gynecol Obstet 133:644-648, 1971
    • (1971) Surg Gynecol Obstet , vol.133 , pp. 644-648
    • Lynch, H.T.1    Krush, A.J.2
  • 6
    • 0345661300 scopus 로고
    • Lynch HT, Fusaro RM eds, New York, Van Nostrand Reinhold Co
    • Lynch HT, Fusaro RM (eds): Cancer-Associated Genodermatoses. New York, Van Nostrand Reinhold Co, 1982
    • (1982) Cancer-Associated Genodermatoses
  • 7
    • 0003738147 scopus 로고    scopus 로고
    • Vogelstein B, Kinzler KW eds, New York, McGraw-Hill
    • Vogelstein B, Kinzler KW (eds): The Genetic Basis of Human Cancer. New York, McGraw-Hill, 1998
    • (1998) The Genetic Basis of Human Cancer
  • 8
    • 18544389716 scopus 로고    scopus 로고
    • Low-penetrance susceptibility to breast cancer due to CHEK2*1100delC in noncarriers of BRCA1 and BRCA2 mutations
    • Meijers-Heijboer H, van den Ouweland A, Klijn J, et al: Low-penetrance susceptibility to breast cancer due to CHEK2*1100delC in noncarriers of BRCA1 and BRCA2 mutations. Nat Genet 31:55-59, 2002
    • (2002) Nat Genet , vol.31 , pp. 55-59
    • Meijers-Heijboer, H.1    van den Ouweland, A.2    Klijn, J.3
  • 9
    • 0032126223 scopus 로고    scopus 로고
    • A step toward genotype-based therapeutic regimens for breast cancer in patients with BRCA2 mutations?
    • Biggs PJ, Bradley A: A step toward genotype-based therapeutic regimens for breast cancer in patients with BRCA2 mutations? J Natl Cancer Inst 90:951-953, 1998
    • (1998) J Natl Cancer Inst , vol.90 , pp. 951-953
    • Biggs, P.J.1    Bradley, A.2
  • 10
    • 0035190979 scopus 로고    scopus 로고
    • Bioinformatic identification of potential autocrine signaling loops in cancers from gene expression profiles
    • Graeber TG, Eisenberg D: Bioinformatic identification of potential autocrine signaling loops in cancers from gene expression profiles. Nat Genet 29:295-300, 2001
    • (2001) Nat Genet , vol.29 , pp. 295-300
    • Graeber, T.G.1    Eisenberg, D.2
  • 11
    • 0035179994 scopus 로고    scopus 로고
    • Genomics and future biological weapons: The need for preventive action by the biomedical community
    • Fraser CM, Dando MR: Genomics and future biological weapons: The need for preventive action by the biomedical community. Nat Genet 29:253-256, 2001
    • (2001) Nat Genet , vol.29 , pp. 253-256
    • Fraser, C.M.1    Dando, M.R.2
  • 12
    • 18244409687 scopus 로고    scopus 로고
    • Gene expression profiling predicts clinical outcome of breast cancer
    • van 't Veer LJ, Dai H, van de Vijver MJ, et al: Gene expression profiling predicts clinical outcome of breast cancer. Nature 415:530-536, 2002
    • (2002) Nature , vol.415 , pp. 530-536
    • van 't Veer, L.J.1    Dai, H.2    van de Vijver, M.J.3
  • 13
    • 0037116832 scopus 로고    scopus 로고
    • Use of proteomic patterns in serum to identify ovarian cancer
    • Petricoin EF, III, Ardekani AM, Hitt BA, et al: Use of proteomic patterns in serum to identify ovarian cancer. Lancet 359:572-577, 2002
    • (2002) Lancet , vol.359 , pp. 572-577
    • Petricoin III, E.F.1    Ardekani, A.M.2    Hitt, B.A.3
  • 14
    • 0037087536 scopus 로고    scopus 로고
    • Clinical characteristics of individuals with germline mutations in BRCA1 and BRCA2: Analysis of 10,000 individuals
    • Frank TS, Deffenbaugh AM, Reid JE, et al: Clinical characteristics of individuals with germline mutations in BRCA1 and BRCA2: Analysis of 10,000 individuals. J Clin Oncol 20:1480-1490, 2002
    • (2002) J Clin Oncol , vol.20 , pp. 1480-1490
    • Frank, T.S.1    Deffenbaugh, A.M.2    Reid, J.E.3
  • 15
    • 0035098503 scopus 로고    scopus 로고
    • Prevalence and penetrance of germline BRCA1 and BRCA2 mutations in a population series of 649 women with ovarian cancer
    • Risch HA, McLaughlin JR, Cole DEC, et al: Prevalence and penetrance of germline BRCA1 and BRCA2 mutations in a population series of 649 women with ovarian cancer. Am J Hum Genet 68:700-710, 2001
    • (2001) Am J Hum Genet , vol.68 , pp. 700-710
    • Risch, H.A.1    McLaughlin, J.R.2    Cole, D.E.C.3
  • 16
    • 0037080326 scopus 로고    scopus 로고
    • Identification and referral of families at high risk for cancer susceptibility
    • Sweet KM, Bradley TL, Westman JA: Identification and referral of families at high risk for cancer susceptibility. J Clin Oncol 20:528-537, 2002
    • (2002) J Clin Oncol , vol.20 , pp. 528-537
    • Sweet, K.M.1    Bradley, T.L.2    Westman, J.A.3
  • 17
    • 0025761596 scopus 로고
    • The potential use of tumor registry data in the recognition and prevention of hereditary and familial cancer
    • David KL, Steiner-Grossman P: The potential use of tumor registry data in the recognition and prevention of hereditary and familial cancer. N Y State J Med 91:150-152, 1991
    • (1991) N Y State J Med , vol.91 , pp. 150-152
    • David, K.L.1    Steiner-Grossman, P.2
  • 18
    • 0025765332 scopus 로고
    • Cancer and the family history trail
    • editorial
    • Lynch HT: Cancer and the family history trail. N Y State J Med 91:145-147, 1991 (editorial)
    • (1991) N Y State J Med , vol.91 , pp. 145-147
    • Lynch, H.T.1
  • 19
    • 0017818820 scopus 로고
    • Genetic and pathologic findings in a kindred with hereditary sarcoma, breast cancer, brain tumors, leukemia, lung, laryngeal, and adrenal cortical carcinoma
    • Lynch HT, Mulcahy GM, Harris RE, et al: Genetic and pathologic findings in a kindred with hereditary sarcoma, breast cancer, brain tumors, leukemia, lung, laryngeal, and adrenal cortical carcinoma. Cancer 41:2055-2064, 1978
    • (1978) Cancer , vol.41 , pp. 2055-2064
    • Lynch, H.T.1    Mulcahy, G.M.2    Harris, R.E.3
  • 20
  • 22
    • 34247204500 scopus 로고
    • 368 Fed2 626 4th Cir
    • Hicks v United States, 368 Fed2 626 (4th Cir 1966)
    • (1966) Hicks v United States
  • 23
    • 84871466248 scopus 로고    scopus 로고
    • O'Brien v Stover, 443 F2 1013 (8th Cir 1971)
    • O'Brien v Stover, 443 F2 1013 (8th Cir 1971)
  • 24
    • 0030074299 scopus 로고    scopus 로고
    • Heredity cancer litigation: A status report
    • Severin MJ: Heredity cancer litigation: A status report. Oncology 10:211-214, 1996
    • (1996) Oncology , vol.10 , pp. 211-214
    • Severin, M.J.1
  • 25
    • 0033569801 scopus 로고    scopus 로고
    • Genetic susceptibility for specific cancers: Medical liability of the clinician
    • Severin MJ: Genetic susceptibility for specific cancers: Medical liability of the clinician Cancer 86:2564-2569, 1999
    • (1999) Cancer , vol.86 , pp. 2564-2569
    • Severin, M.J.1
  • 26
    • 0030743572 scopus 로고    scopus 로고
    • Breast carcinoma litigation: Medical questions, legal answers
    • suppl
    • Severin MJ: Breast carcinoma litigation: Medical questions, legal answers. Cancer 80:600-605, 1997 (suppl)
    • (1997) Cancer , vol.80 , pp. 600-605
    • Severin, M.J.1
  • 27
    • 0028923465 scopus 로고
    • Recommendations for standardized human pedigree nomenclature. Pedigree Standardization Task Force of the National Society of Genetic Counselors
    • Bennett RL, Steinhaus KA, Uhrich SB, et al: Recommendations for standardized human pedigree nomenclature. Pedigree Standardization Task Force of the National Society of Genetic Counselors. Am J Hum Genet 56:745-752, 1995
    • (1995) Am J Hum Genet , vol.56 , pp. 745-752
    • Bennett, R.L.1    Steinhaus, K.A.2    Uhrich, S.B.3
  • 28
    • 0035864981 scopus 로고    scopus 로고
    • Family Information Service and hereditary cancer
    • Lynch HT: Family Information Service and hereditary cancer. Cancer 91:625-628, 2001
    • (2001) Cancer , vol.91 , pp. 625-628
    • Lynch, H.T.1
  • 29
    • 8544231343 scopus 로고    scopus 로고
    • Breast cancer genetics: Heterogeneity, molecular genetics, syndrome diagnosis, and genetic counseling
    • Bland KI, Copeland EMI eds, ed 2. Philadelphia, PA, W. B. Saunders
    • Lynch HT, Lemon SJ, Marcus JN, et al: Breast cancer genetics: heterogeneity, molecular genetics, syndrome diagnosis, and genetic counseling, in Bland KI, Copeland EMI (eds): The Breast: Comprehensive Management of Benign and Malignant Diseases, vol. 1, ed 2. Philadelphia, PA, W. B. Saunders, 1998, pp 370-394
    • (1998) The Breast: Comprehensive Management of Benign and Malignant Diseases , vol.1 , pp. 370-394
    • Lynch, H.T.1    Lemon, S.J.2    Marcus, J.N.3
  • 30
    • 0008195461 scopus 로고    scopus 로고
    • A descriptive study of BRCA1 testing and reactions to disclosure of test results
    • Lynch HT, Lemon SJ, Durham C, et al: A descriptive study of BRCA1 testing and reactions to disclosure of test results. Cancer 79:2219-2228, 1997
    • (1997) Cancer , vol.79 , pp. 2219-2228
    • Lynch, H.T.1    Lemon, S.J.2    Durham, C.3
  • 31
    • 18544381115 scopus 로고    scopus 로고
    • Insurance reimbursement for risk-reducing mastectomy and oophorectomy in women with BRCA1 or BRCA2 mutations
    • Kauff ND, Scheuer L, Robson ME, et al: Insurance reimbursement for risk-reducing mastectomy and oophorectomy in women with BRCA1 or BRCA2 mutations. Genet Med 3:422-425, 2001
    • (2001) Genet Med , vol.3 , pp. 422-425
    • Kauff, N.D.1    Scheuer, L.2    Robson, M.E.3
  • 32
    • 0036164587 scopus 로고    scopus 로고
    • Health insurance and discrimination concerns and BRCA1/2 testing in a clinic population
    • Peterson EA, Milliron KJ, Lewis KE, et al: Health insurance and discrimination concerns and BRCA1/2 testing in a clinic population. Cancer Epidemiol Biomarkers Prev 11:79-87, 2002
    • (2002) Cancer Epidemiol Biomarkers Prev , vol.11 , pp. 79-87
    • Peterson, E.A.1    Milliron, K.J.2    Lewis, K.E.3
  • 33
    • 2042448108 scopus 로고    scopus 로고
    • Qualitative cancer genetic counseling research, part I: Ethnography in a cancer clinic
    • Peters JA, McAllister CL, Rubinstein WS: Qualitative cancer genetic counseling research, part I: Ethnography in a cancer clinic. J Genet Couns 10:133-150, 2001
    • (2001) J Genet Couns , vol.10 , pp. 133-150
    • Peters, J.A.1    McAllister, C.L.2    Rubinstein, W.S.3
  • 34
    • 20444483510 scopus 로고    scopus 로고
    • Qualitative cancer genetic counseling research, part II: Findings from an exploratory ethnograhic study in a cancer clinic
    • Peters JA, McAllister CL, Rubinstein WS: Qualitative cancer genetic counseling research, part II: Findings from an exploratory ethnograhic study in a cancer clinic. J Genet Couns 10:151-168, 2001
    • (2001) J Genet Couns , vol.10 , pp. 151-168
    • Peters, J.A.1    McAllister, C.L.2    Rubinstein, W.S.3
  • 35
    • 0035824069 scopus 로고    scopus 로고
    • Efficacy of bilateral prophylactic mastectomy in BRCA1 and BRCA2 gene mutation carriers
    • Hartmann LC, Sellers TA, Schaid DJ, et al: Efficacy of bilateral prophylactic mastectomy in BRCA1 and BRCA2 gene mutation carriers. J Natl Cancer Inst 93:1633-1637, 2001
    • (2001) J Natl Cancer Inst , vol.93 , pp. 1633-1637
    • Hartmann, L.C.1    Sellers, T.A.2    Schaid, D.J.3
  • 36
    • 0033199926 scopus 로고    scopus 로고
    • Breast cancer risk after bilateral prophylactic oophorectomy in BRCA1 mutation carriers
    • Rebbeck TR, Levin AM, Eisen A, et al: Breast cancer risk after bilateral prophylactic oophorectomy in BRCA1 mutation carriers. J Natl Cancer Inst 91:1475-1479, 1999
    • (1999) J Natl Cancer Inst , vol.91 , pp. 1475-1479
    • Rebbeck, T.R.1    Levin, A.M.2    Eisen, A.3
  • 37
    • 0037162110 scopus 로고    scopus 로고
    • Prophylactic oophorectomy in carriers of BRCA1 or BRCA2 mutations
    • Rebbeck TR, Lynch HT, Neuhausen SL, et al: Prophylactic oophorectomy in carriers of BRCA1 or BRCA2 mutations. N Engl J Med 346:1616-1622, 2002
    • (2002) N Engl J Med , vol.346 , pp. 1616-1622
    • Rebbeck, T.R.1    Lynch, H.T.2    Neuhausen, S.L.3
  • 38
    • 0034597916 scopus 로고    scopus 로고
    • Tamoxifen and risk of contralateral breast cancer in BRCA1 and BRCA2 mutation carriers: A case-control study
    • Narod SA, Brunet J-S, Ghadirian P, et al: Tamoxifen and risk of contralateral breast cancer in BRCA1 and BRCA2 mutation carriers: A case-control study. Lancet 356:1876-1881, 2000
    • (2000) Lancet , vol.356 , pp. 1876-1881
    • Narod, S.A.1    Brunet, J.-S.2    Ghadirian, P.3
  • 40
    • 0036498727 scopus 로고    scopus 로고
    • Outcome of preventive surgery and screening for breast and ovarian cancer in BRCA mutation carriers
    • Scheuer L, Kauff N, Robson M, et al: Outcome of preventive surgery and screening for breast and ovarian cancer in BRCA mutation carriers. J Clin Oncol 20:1260-1268, 2002
    • (2002) J Clin Oncol , vol.20 , pp. 1260-1268
    • Scheuer, L.1    Kauff, N.2    Robson, M.3
  • 41
    • 0034017713 scopus 로고    scopus 로고
    • Prophylactic surgery in women with a hereditary predisposition to breast and ovarian cancer
    • Eisen A, Rebbeck TR, Wood WC, et al: Prophylactic surgery in women with a hereditary predisposition to breast and ovarian cancer. J Clin Oncol 18:1980-1995, 2000
    • (2000) J Clin Oncol , vol.18 , pp. 1980-1995
    • Eisen, A.1    Rebbeck, T.R.2    Wood, W.C.3
  • 42
    • 0030474392 scopus 로고    scopus 로고
    • Autonomy of the epithelial phenotype in human ovarian surface epithelium: Changes with neoplastic progression and with a family history of ovarian cancer
    • Dyck HG, Hamilton TC, Godwin AK, et al: Autonomy of the epithelial phenotype in human ovarian surface epithelium: Changes with neoplastic progression and with a family history of ovarian cancer. Int J Cancer (Pred Oncol) 69:429-436, 1996
    • (1996) Int J Cancer (Pred Oncol) , vol.69 , pp. 429-436
    • Dyck, H.G.1    Hamilton, T.C.2    Godwin, A.K.3
  • 43
    • 0034320308 scopus 로고    scopus 로고
    • Screening for ovarian cancer: What we know, what we need to know
    • Hensley ML, Castiel M, Robson ME: Screening for ovarian cancer: What we know, what we need to know. Oncology 14:1601-1607, 2001
    • (2001) Oncology , vol.14 , pp. 1601-1607
    • Hensley, M.L.1    Castiel, M.2    Robson, M.E.3
  • 44
    • 0003189653 scopus 로고
    • Ovarian cancer: Screening, treatment, and follow-up
    • National Institutes of Health Consensus Development Conference Statement
    • National Institutes of Health Consensus Development Conference Statement. Ovarian cancer: Screening, treatment, and follow-up. Gynecol Oncol 55:S4-S14, 1994
    • (1994) Gynecol Oncol , vol.55
  • 45
    • 0028242806 scopus 로고
    • Screening for ovarian cancer: Hopeful and wishful thinking
    • Droegemueller W: Screening for ovarian cancer: Hopeful and wishful thinking. Am J Obstet Gynecol 170:1095-1098, 1994
    • (1994) Am J Obstet Gynecol , vol.170 , pp. 1095-1098
    • Droegemueller, W.1
  • 46
    • 0034785677 scopus 로고    scopus 로고
    • Surveillance or surgery? A description of the factors that influence high risk premenopausal women's decisions about prophylactic oophorectomy
    • Hallowell N, Jacobs I, Richards M, et al: Surveillance or surgery? A description of the factors that influence high risk premenopausal women's decisions about prophylactic oophorectomy. J Med Genet 38:683-691, 2001
    • (2001) J Med Genet , vol.38 , pp. 683-691
    • Hallowell, N.1    Jacobs, I.2    Richards, M.3
  • 47
    • 0035913275 scopus 로고    scopus 로고
    • Breast cancer after prophylactic bilateral mastectomy in women with a BRCA1 or BRCA2 mutation
    • Meijers-Heijboer H, van Geel B, van Putten WLJ, et al: Breast cancer after prophylactic bilateral mastectomy in women with a BRCA1 or BRCA2 mutation. N Engl J Med 345:159-164, 2001
    • (2001) N Engl J Med , vol.345 , pp. 159-164
    • Meijers-Heijboer, H.1    van Geel, B.2    van Putten, W.L.J.3
  • 48
    • 0032879132 scopus 로고    scopus 로고
    • Attitudes toward prophylactic oophorectomy and screening utilization in women at increased risk of developing hereditary breast/ovarian cancer
    • Meiser B, Butow P, Barratt A, et al: Attitudes toward prophylactic oophorectomy and screening utilization in women at increased risk of developing hereditary breast/ovarian cancer. Gynecol Oncol 75:122-129, 1999
    • (1999) Gynecol Oncol , vol.75 , pp. 122-129
    • Meiser, B.1    Butow, P.2    Barratt, A.3
  • 49
    • 0033928675 scopus 로고    scopus 로고
    • Prophylactic surgery decisions and surveillance practices one year following BRCA1/2 testing
    • Lerman C, Hughes C, Croyle RT, et al: Prophylactic surgery decisions and surveillance practices one year following BRCA1/2 testing. Prev Med 31:75-80, 2000
    • (2000) Prev Med , vol.31 , pp. 75-80
    • Lerman, C.1    Hughes, C.2    Croyle, R.T.3
  • 50
    • 0036605379 scopus 로고    scopus 로고
    • BRCAPRO validation, sensitivity of genetic testing of BRCA1/BRCA2 and prevalence of other breast cancer susceptibility genes
    • Berry DA, Iversen ES, Jr., Gudbjartsson DF, et al: BRCAPRO validation, sensitivity of genetic testing of BRCA1/BRCA2 and prevalence of other breast cancer susceptibility genes. J Clin Oncol 20:2701-2712, 2002
    • (2002) J Clin Oncol , vol.20 , pp. 2701-2712
    • Berry, D.A.1    Iversen Jr., E.S.2    Gudbjartsson, D.F.3
  • 51
    • 0031712163 scopus 로고    scopus 로고
    • A family with three germline mutations in BRCA1 and BRCA2
    • Liede A, Metcalfe K, Offit K, et al: A family with three germline mutations in BRCA1 and BRCA2. Clin Genet 54:215-218, 1998
    • (1998) Clin Genet , vol.54 , pp. 215-218
    • Liede, A.1    Metcalfe, K.2    Offit, K.3
  • 52
    • 0034650718 scopus 로고    scopus 로고
    • Predominance of brain tumors in an extended Li-Fraumeni (SBLA) kindred, including a case of Sturge-Weber syndrome
    • Lynch HT, McComb RD, Osborn NK, et al: Predominance of brain tumors in an extended Li-Fraumeni (SBLA) kindred, including a case of Sturge-Weber syndrome. Cancer 88:433-439, 2000
    • (2000) Cancer , vol.88 , pp. 433-439
    • Lynch, H.T.1    McComb, R.D.2    Osborn, N.K.3
  • 53
    • 0033668758 scopus 로고    scopus 로고
    • Uncovering functionally relevant signaling pathways using microarray-based expression profiling
    • Harkin DP: Uncovering functionally relevant signaling pathways using microarray-based expression profiling. Oncologist 5:501-507, 2000
    • (2000) Oncologist , vol.5 , pp. 501-507
    • Harkin, D.P.1
  • 54
    • 0033527790 scopus 로고    scopus 로고
    • Breast cancer genes and DNA repair
    • Venkitaraman AR: Breast cancer genes and DNA repair. Science 286:1100-1102, 1999
    • (1999) Science , vol.286 , pp. 1100-1102
    • Venkitaraman, A.R.1
  • 55
    • 0031472370 scopus 로고    scopus 로고
    • Association of BRCA1 with Rad51 in mitotic and meiotic cells
    • Scully R, Chen J, Plug A, et al: Association of BRCA1 with Rad51 in mitotic and meiotic cells. Cell 88:265-275, 1997
    • (1997) Cell , vol.88 , pp. 265-275
    • Scully, R.1    Chen, J.2    Plug, A.3
  • 56
    • 0035853077 scopus 로고    scopus 로고
    • A single nucleotide polymorphism in the RAD51 gene modifies cancer risk in BRCA2 but not BRCA1 carriers
    • Levy-Lahad E, Lahad A, Eisenberg S, et al: A single nucleotide polymorphism in the RAD51 gene modifies cancer risk in BRCA2 but not BRCA1 carriers. Proc Natl Acad Sci USA 98:3232-3236, 2001
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 3232-3236
    • Levy-Lahad, E.1    Lahad, A.2    Eisenberg, S.3
  • 57
    • 0026409331 scopus 로고
    • Incidence of cancer in 161 families affected by ataxia-telangiectasia
    • Swift M, Morrell D, Massey RB, et al: Incidence of cancer in 161 families affected by ataxia-telangiectasia. N Engl J Med 325:1831-1836, 1991
    • (1991) N Engl J Med , vol.325 , pp. 1831-1836
    • Swift, M.1    Morrell, D.2    Massey, R.B.3
  • 58
    • 0033911566 scopus 로고    scopus 로고
    • ATM-heterozygous germline mutations contribute to breast cancer susceptibility
    • Broeks A, Urbanus JH, Floore AN, et al: ATM-heterozygous germline mutations contribute to breast cancer susceptibility. Hum Genet 66:494-500, 2000
    • (2000) Hum Genet , vol.66 , pp. 494-500
    • Broeks, A.1    Urbanus, J.H.2    Floore, A.N.3
  • 59
    • 0030933762 scopus 로고    scopus 로고
    • Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2
    • Sharan SK, Morimatsu M, Albrecht U, et al: Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2. Nature 386:804-810, 1997
    • (1997) Nature , vol.386 , pp. 804-810
    • Sharan, S.K.1    Morimatsu, M.2    Albrecht, U.3
  • 60
    • 0030659153 scopus 로고    scopus 로고
    • Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation
    • Connor F, Bertwistle D, Mee PJ, et al: Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation. Nat Genet 17:423-430, 1997
    • (1997) Nat Genet , vol.17 , pp. 423-430
    • Connor, F.1    Bertwistle, D.2    Mee, P.J.3
  • 61
    • 0032126029 scopus 로고    scopus 로고
    • Double-strand break repair deficiency and radiation sensitivity in BRCA2 mutant cancer cells
    • Abbott DW, Freeman ML, Holt JT: Double-strand break repair deficiency and radiation sensitivity in BRCA2 mutant cancer cells. J Natl Cancer Inst 90:978-985, 1998
    • (1998) J Natl Cancer Inst , vol.90 , pp. 978-985
    • Abbott, D.W.1    Freeman, M.L.2    Holt, J.T.3
  • 62
    • 0032727664 scopus 로고    scopus 로고
    • Molecular biology in radiation oncology. Radiation oncology perspective of BRCA1 and BRCA2
    • suppl
    • Coleman CN: Molecular biology in radiation oncology. Radiation oncology perspective of BRCA1 and BRCA2. Acta Oncol 38:55-59, 1999 (suppl)
    • (1999) Acta Oncol , vol.38 , pp. 55-59
    • Coleman, C.N.1
  • 63
    • 84871465424 scopus 로고    scopus 로고
    • Friedenson B: Is mammography indicated for women with defective BRCA genes? Implications of recent scientific advances for the diagnosis, treatment, and prevention of hereditary breast cancer. Medscape Portals, Inc., Medscape General Medicine 2, 2000 http://www.medscape.com/viewarticle/408048. Accesses January 6, 2003
    • Friedenson B: Is mammography indicated for women with defective BRCA genes? Implications of recent scientific advances for the diagnosis, treatment, and prevention of hereditary breast cancer. Medscape Portals, Inc., Medscape General Medicine 2, 2000 http://www.medscape.com/viewarticle/408048. Accesses January 6, 2003
  • 64
    • 0034306318 scopus 로고    scopus 로고
    • Effect of radiotherapy after breast-conserving treatment in women with breast cancer and germline BRCA1/2 mutations
    • Pierce LJ, Strawderman M, Narod SA, et al: Effect of radiotherapy after breast-conserving treatment in women with breast cancer and germline BRCA1/2 mutations. J Clin Oncol 18:3360-3369, 2000
    • (2000) J Clin Oncol , vol.18 , pp. 3360-3369
    • Pierce, L.J.1    Strawderman, M.2    Narod, S.A.3
  • 65
    • 0032887486 scopus 로고    scopus 로고
    • BRCA1/BRCA2 germline mutations in locally recurrent breast cancer patients after lumpectomy and radiation therapy: Implications for breast-conserving management in patients with BRCA1/BRCA2 mutations
    • Turner B, Harrold E, Matloff E, et al: BRCA1/BRCA2 germline mutations in locally recurrent breast cancer patients after lumpectomy and radiation therapy: Implications for breast-conserving management in patients with BRCA1/BRCA2 mutations. J Clin Oncol 17:3017-3024, 1999
    • (1999) J Clin Oncol , vol.17 , pp. 3017-3024
    • Turner, B.1    Harrold, E.2    Matloff, E.3
  • 66
    • 0030811692 scopus 로고    scopus 로고
    • BRCA1 and BRCA2 hereditary breast carcinoma phenotypes
    • suppl
    • Marcus JN, Page DL, Watson P, et al: BRCA1 and BRCA2 hereditary breast carcinoma phenotypes. Cancer 80:543-556, 1997 (suppl)
    • (1997) Cancer , vol.80 , pp. 543-556
    • Marcus, J.N.1    Page, D.L.2    Watson, P.3
  • 68
    • 13344262707 scopus 로고    scopus 로고
    • Hereditary breast cancer: Pathobiology, prognosis, and BRCA1 and BRCA2 gene linkage
    • Marcus JN, Watson P, Page DL, et al: Hereditary breast cancer: Pathobiology, prognosis, and BRCA1 and BRCA2 gene linkage. Cancer 77:697-709, 1996
    • (1996) Cancer , vol.77 , pp. 697-709
    • Marcus, J.N.1    Watson, P.2    Page, D.L.3
  • 69
    • 0036569877 scopus 로고    scopus 로고
    • The pathology of familial breast cancer: Predictive value of immunohistochemical markers estrogen receptor, progesterone receptor, HER-2, and p53 in patients with mutations in BRCA1 and BRCA2
    • Lakhani SR, van de Vijver MJ, Jacquemier J, et al: The pathology of familial breast cancer: Predictive value of immunohistochemical markers estrogen receptor, progesterone receptor, HER-2, and p53 in patients with mutations in BRCA1 and BRCA2. J Clin Oncol 20:2310-2318, 2002
    • (2002) J Clin Oncol , vol.20 , pp. 2310-2318
    • Lakhani, S.R.1    van de Vijver, M.J.2    Jacquemier, J.3
  • 70
    • 0034680102 scopus 로고    scopus 로고
    • Molecular portraits of human breast tumours
    • Perou CM, Sorlie T, Eisen MB, et al: Molecular portraits of human breast tumours. Nature 406:747-752, 2000
    • (2000) Nature , vol.406 , pp. 747-752
    • Perou, C.M.1    Sorlie, T.2    Eisen, M.B.3
  • 71
    • 0035845511 scopus 로고    scopus 로고
    • Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
    • Sorlie T, Perou CM, Tibshirani R, et al: Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci U S A 98:10869-10874, 2001
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 10869-10874
    • Sorlie, T.1    Perou, C.M.2    Tibshirani, R.3
  • 72
    • 0035881617 scopus 로고    scopus 로고
    • Estrogen receptor status in breast cancer is associated with remarkably distinct gene expression patterns
    • Gruvberger S, Ringner M, Chen Y, et al: Estrogen receptor status in breast cancer is associated with remarkably distinct gene expression patterns. Cancer Res 61:5979-5984, 2001
    • (2001) Cancer Res , vol.61 , pp. 5979-5984
    • Gruvberger, S.1    Ringner, M.2    Chen, Y.3
  • 73
    • 0035956894 scopus 로고    scopus 로고
    • High sensitivity array analysis of gene expression for the early detection of disseminated breast tumor cells in peripheral blood
    • Martin KJ, Graner E, Li Y, et al: High sensitivity array analysis of gene expression for the early detection of disseminated breast tumor cells in peripheral blood. Proc Natl Acad Sci USA 98:2646-2651, 2001
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 2646-2651
    • Martin, K.J.1    Graner, E.2    Li, Y.3
  • 74
    • 0033891762 scopus 로고    scopus 로고
    • Monitoring the expression profiles of doxorubicin-induced and doxorubicin-resistant cancer cells by cDNA microarray
    • Kudoh K, Ramanna M, Ravatn R, et al: Monitoring the expression profiles of doxorubicin-induced and doxorubicin-resistant cancer cells by cDNA microarray. Cancer Res 60:4161-4166, 2000
    • (2000) Cancer Res , vol.60 , pp. 4161-4166
    • Kudoh, K.1    Ramanna, M.2    Ravatn, R.3
  • 75
    • 0032547564 scopus 로고    scopus 로고
    • Polychemotherapy for early breast cancer: An overview of the randomised trials
    • Early Breast Cancer Trialists' Collaborative Group
    • Early Breast Cancer Trialists' Collaborative Group: Polychemotherapy for early breast cancer: An overview of the randomised trials. Lancet 352:930-942, 1998
    • (1998) Lancet , vol.352 , pp. 930-942
  • 76
    • 0032537396 scopus 로고    scopus 로고
    • Tamoxifen for early breast cancer: An overview of the randomised trials
    • Early Breast Cancer Trialists' Collaborative Group
    • Early Breast Cancer Trialists' Collaborative Group: Tamoxifen for early breast cancer: An overview of the randomised trials. Lancet 351:1451-1467, 1998
    • (1998) Lancet , vol.351 , pp. 1451-1467
  • 77
    • 13044304179 scopus 로고    scopus 로고
    • Distinctive gene expression patterns in human mammary epithelial cells and breast cancers
    • Perou CM, Jeffrey SS, van de Rijn M, et al: Distinctive gene expression patterns in human mammary epithelial cells and breast cancers. Proc Natl Acad Sci USA 96:9212-9217, 1999
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 9212-9217
    • Perou, C.M.1    Jeffrey, S.S.2    van de Rijn, M.3
  • 78
    • 0034655160 scopus 로고    scopus 로고
    • Linking gene expression patterns to therapeutic groups in breast cancer
    • Martin KJ, Kritzman BM, Price LM, et al: Linking gene expression patterns to therapeutic groups in breast cancer. Cancer Res 60:2232-2238, 2000
    • (2000) Cancer Res , vol.60 , pp. 2232-2238
    • Martin, K.J.1    Kritzman, B.M.2    Price, L.M.3
  • 79
    • 0035392954 scopus 로고    scopus 로고
    • Identification of gene expression profiles that predict the aggressive behavior of breast cancer cells
    • Zajchowski DA, Bartholdi MF, Gong Y, et al: Identification of gene expression profiles that predict the aggressive behavior of breast cancer cells. Cancer Res 61:5168-5178, 2001
    • (2001) Cancer Res , vol.61 , pp. 5168-5178
    • Zajchowski, D.A.1    Bartholdi, M.F.2    Gong, Y.3
  • 80
    • 0035949684 scopus 로고    scopus 로고
    • Predicting the clinical status of human breast cancer by using gene expression profiles
    • West M, Blanchette C, Dressman H, et al: Predicting the clinical status of human breast cancer by using gene expression profiles. Proc Natl Acad Sci USA 98:11462-11467, 2001
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 11462-11467
    • West, M.1    Blanchette, C.2    Dressman, H.3
  • 81
    • 0035931947 scopus 로고    scopus 로고
    • Gene expression profiles in hereditary breast cancer
    • Hedenfalk I, Duggan D, Chen Y, et al: Gene expression profiles in hereditary breast cancer. N Engl J Med 344:539-548, 2001
    • (2001) N Engl J Med , vol.344 , pp. 539-548
    • Hedenfalk, I.1    Duggan, D.2    Chen, Y.3
  • 82
    • 0031832541 scopus 로고    scopus 로고
    • Sequence analysis of BRCA1 and BRCA2: Correlation of mutations with family history and ovarian cancer risk
    • Frank TS, Manley SA, Olopade OI, et al: Sequence analysis of BRCA1 and BRCA2: Correlation of mutations with family history and ovarian cancer risk. J Clin Oncol 16:2417-2425, 1998
    • (1998) J Clin Oncol , vol.16 , pp. 2417-2425
    • Frank, T.S.1    Manley, S.A.2    Olopade, O.I.3
  • 83
    • 0035810147 scopus 로고    scopus 로고
    • Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
    • Druker BJ, Talpaz M, Resta DJ, et al: Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N Engl J Med 344:1031-1037, 2001
    • (2001) N Engl J Med , vol.344 , pp. 1031-1037
    • Druker, B.J.1    Talpaz, M.2    Resta, D.J.3
  • 84
    • 0035810142 scopus 로고    scopus 로고
    • Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome
    • Druker BJ, Sawyers CL, Kantarjian H, et al: Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome. N Engl J Med 344:1038-1042, 2001
    • (2001) N Engl J Med , vol.344 , pp. 1038-1042
    • Druker, B.J.1    Sawyers, C.L.2    Kantarjian, H.3
  • 85
    • 0035899935 scopus 로고    scopus 로고
    • Cost-effectiveness of microsatellite instability screening as a method for detecting hereditary nonpolyposis colorectal cancer
    • Ramsey SD, Clarke L, Etzioni R, et al: Cost-effectiveness of microsatellite instability screening as a method for detecting hereditary nonpolyposis colorectal cancer. Ann Intern Med 135:577-588, 2001
    • (2001) Ann Intern Med , vol.135 , pp. 577-588
    • Ramsey, S.D.1    Clarke, L.2    Etzioni, R.3
  • 86
    • 0031931894 scopus 로고    scopus 로고
    • Decision analysis of prophylactic mastectomy and oophorectomy in BRCA1-positive or BRCA2-positive patients
    • Grann VR, Panageas KS, Whang W, et al: Decision analysis of prophylactic mastectomy and oophorectomy in BRCA1-positive or BRCA2-positive patients. J Clin Oncol 16:979-985, 1998
    • (1998) J Clin Oncol , vol.16 , pp. 979-985
    • Grann, V.R.1    Panageas, K.S.2    Whang, W.3
  • 87
    • 0034594659 scopus 로고    scopus 로고
    • Life expectancy gains from cancer prevention strategies for women with breast cancer and BRCA1 or BRCA2 mutations
    • Schrag D, Kuntz KM, Garber JE, et al: Life expectancy gains from cancer prevention strategies for women with breast cancer and BRCA1 or BRCA2 mutations. JAMA 283:617-624, 2000
    • (2000) JAMA , vol.283 , pp. 617-624
    • Schrag, D.1    Kuntz, K.M.2    Garber, J.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.