Inhibition of heat shock protein 90 (hsp90) in proliferating endothelial cells uncouples endothelial nitric oxide synthase activity

Free Radical Biology and Medicine

Volumn 34, Issue 2, 2003, Pages 269-276

  Ou, Jingsong ^a   Ou, Zhijun ^a   Ackerman, Allan W ^a   Oldham, Keith T ^a   Pritchard Jr , Kirkwood A ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Endothelial cells; eNOS; Free radicals; hsp90; Nitric oxide; Superoxide anion

Indexed keywords

CALCIMYCIN; HEAT SHOCK PROTEIN 90; N(G) NITROARGININE METHYL ESTER; NITRATE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRITE; OXYGEN; RADICICOL; SUPEROXIDE;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENDOTHELIUM CELL; ENZYME ACTIVITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; VASCULAR ENDOTHELIUM; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CATTLE; CELL DIVISION; CELLS, CULTURED; ENDOTHELIUM; ENZYME INHIBITORS; HSP90 HEAT-SHOCK PROTEINS; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; SUPEROXIDES;

EID: 0037438835     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(02)01299-6     Document Type: Article

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