Concentration-dependence of biomarkers of exposure of methylenediphenyl-diisocyanate following acute inhalation exposure of rats

Toxicology

Volumn 185, Issue 1-2, 2003, Pages 35-48

  Pauluhn, Jürgen ^a   Leng, Gabriele ^b  

^a Building no 514 ^*  (Germany)

^b BAYER AG   (Germany)

Author keywords

4,4 Methylenediphenyldianiline; Biomarkers of exposure; Biomonitoring; Dosimetry; Hemoglobin adducts; Inhalation exposure; Methylenediphenyl 4,4 diisocyanate; Respiratory minute volume; Urinary metabolites

Indexed keywords

BIOLOGICAL MARKER; CREATININE; DIPHENYLMETHANE 4,4' DIISOCYANATE;

AEROSOL; AIR SAMPLING; ANIMAL EXPERIMENT; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; HEMOGLOBIN DETERMINATION; HYDROLYSIS; INHALATION; LUNG MINUTE VOLUME; MALE; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; RAT; URINE LEVEL;

ADMINISTRATION, INHALATION; ANILINE COMPOUNDS; ANIMALS; BIOLOGICAL MARKERS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL MONITORING; HEMOGLOBINS; INHALATION EXPOSURE; IRRITANTS; ISOCYANATES; LUNG VOLUME MEASUREMENTS; MALE; POLYURETHANES; RATS; RATS, WISTAR; RESPIRATION; SPECIFIC PATHOGEN-FREE ORGANISMS;

ANIMALIA;

EID: 0037436381     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(02)00585-1     Document Type: Article

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