Chronic pulmonary effects of respirable methylene diphenyl diisocyanate (MDI) aerosol in rats: Combination of findings from two bioassays

Archives of Toxicology

Volumn 75, Issue 3, 2001, Pages 159-175

  Feron, V J ^a   Kittel, B ^b   Kuper, C F ^a   Ernst, H ^c   Rittinghausen, S ^c   Muhle, H ^c   Koch, W ^c   Gamer, A ^b   Mallett, A K ^d   Hoffmann, H D ^b  

^a TNO   (Netherlands)

^b BASF SE   (Germany)

^c FRAUNHOFER INSTITUTE FOR TOXICOLOGY AND EXPERIMENTAL MEDICINE   (Germany)

^d Shell Scenarios Team Shell International Shell Centre   (United Kingdom)

Author keywords

Combined long term rat bioassays; Inhalation; Methylene diphenyl diisocyanate (MDI); Pulmonary effects

Indexed keywords

CARBENOID; CYANIC ACID DERIVATIVE;

ANIMAL EXPERIMENT; ARTICLE; BIOASSAY; CARCINOGENICITY; EXPOSURE; FEMALE; FIBROSING ALVEOLITIS; HISTOPATHOLOGY; HYPERPLASIA; INFLAMMATION; LUNG ADENOMA; LUNG INJURY; LUNG TOXICITY; LUNG WEIGHT; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RISK ASSESSMENT;

ADENOMA; ADMINISTRATION, INHALATION; AEROSOLS; ANIMALS; BODY WEIGHT; CARCINOGENS; CHRONIC DISEASE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HYPERPLASIA; INHALATION EXPOSURE; ISOCYANATES; LONGEVITY; LUNG NEOPLASMS; MALE; ORGAN SIZE; PULMONARY FIBROSIS; RATS; RATS, WISTAR;

EID: 0035030414     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002040100223     Document Type: Article

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