Analysis of markers of exposure to polymeric methylene-diphenyl diisocyanate (pMDI) in rats: A comparison of dermal and inhalation routes of exposure

Experimental and Toxicologic Pathology

Volumn 54, Issue 2, 2002, Pages 135-146

  Pauluhn, Jürgen ^a   Lewalter, Jürgen ^a  

^a BAYER AG   (Germany)

Author keywords

Biomonitoring; Dermal and inhalation exposure; Hemoglobin adducts; Markers of exposure; MDA; MDI; Monomeric and oligomeric MDI

Indexed keywords

DIPHENYLMETHANE 4,4' DIISOCYANATE; ISOCYANIC ACID DERIVATIVE; POLYMER; ALLERGEN; BIOLOGICAL MARKER; POLYMERIC 4,4' DIPHENYLMETHANE DIISOCYANATE; POLYMERIC 4,4'-DIPHENYLMETHANE DIISOCYANATE; POLYURETHAN;

AEROSOL; AIR MONITORING; ANIMAL MODEL; ARTICLE; DOSIMETRY; ENVIRONMENTAL EXPOSURE; INTERMETHOD COMPARISON; NONHUMAN; RAT; RESPIRATORY SYSTEM; SKIN; ANIMAL; COMPARATIVE STUDY; INHALATIONAL DRUG ADMINISTRATION; INTRADERMAL DRUG ADMINISTRATION; LABORATORY DIAGNOSIS; MALE; METABOLISM; WISTAR RAT;

ANIMALIA; VERTEBRATA;

ADMINISTRATION, CUTANEOUS; ADMINISTRATION, INHALATION; ALLERGENS; ANIMALS; BIOLOGICAL MARKERS; FALSE POSITIVE REACTIONS; ISOCYANATES; MALE; POLYURETHANES; RATS; RATS, WISTAR;

EID: 0036668353     PISSN: 09402993     EISSN: None     Source Type: Journal    
DOI: 10.1078/0940-2993-00242     Document Type: Article

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