메뉴 건너뛰기




Volumn 60, Issue 7, 2003, Pages 1071-1076

DHEA treatment of Alzheimer's disease: A randomized, double-blind, placebo-controlled study

(18)  Wolkowitz, O M a,i   Kramer, J H a   Reus, V I a   Costa, M M a   Yaffe, K a   Walton, P a   Raskind, M b   Peskind, E b   Newhouse, P c   Sack, D d   De Souza, E e,f   Sadowsky, C g   Roberts, E h   Schaerf, F j   Strauss, A j   Charles, L k   Wecker, N l   Segal, M l  

f SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

PLACEBO; PRASTERONE;

EID: 0037426387     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/01.WNL.0000052994.54660.58     Document Type: Article
Times cited : (102)

References (29)
  • 1
    • 0030630595 scopus 로고    scopus 로고
    • Neurosteroids: Of the nervous system, by the nervous system, for the nervous system
    • Baulieu EE. Neurosteroids: of the nervous system, by the nervous system, for the nervous system. Recent Prog Horm Res 1997;52:1-32.
    • (1997) Recent Prog Horm Res , vol.52 , pp. 1-32
    • Baulieu, E.E.1
  • 2
    • 0027469976 scopus 로고
    • Age and sex differences of dehydroepiandrosterone sulfate (DHEAS) and cortisol (CRT) plasma levels in normal controls and Alzheimer's disease (AD)
    • Leblhuber F, Neubauer C, Peichl M, et al. Age and sex differences of dehydroepiandrosterone sulfate (DHEAS) and cortisol (CRT) plasma levels in normal controls and Alzheimer's disease (AD). Psychopharmacology 1993;111:23-26.
    • (1993) Psychopharmacology , vol.111 , pp. 23-26
    • Leblhuber, F.1    Neubauer, C.2    Peichl, M.3
  • 3
    • 0033647320 scopus 로고    scopus 로고
    • Pineal and pituitary- adrenocortical function in physiological aging and in senile dementia
    • Ferrari E, Arcaini A, Gornati R, et al. Pineal and pituitary- adrenocortical function in physiological aging and in senile dementia. Exp Gerontol 2000;35:1239-1250.
    • (2000) Exp Gerontol , vol.35 , pp. 1239-1250
    • Ferrari, E.1    Arcaini, A.2    Gornati, R.3
  • 5
    • 17544396291 scopus 로고    scopus 로고
    • Association between changes in adrenal secretion and cerebral morphometric correlates in normal aging and senile dementia
    • Magri F, Terenzi F, Ricciardi T, et al. Association between changes in adrenal secretion and cerebral morphometric correlates in normal aging and senile dementia. Dement Geriatr Cogn Disord 2000;11:90-99.
    • (2000) Dement Geriatr Cogn Disord , vol.11 , pp. 90-99
    • Magri, F.1    Terenzi, F.2    Ricciardi, T.3
  • 6
    • 0033847691 scopus 로고    scopus 로고
    • Hippocampal perfusion and pituitary-adrenal axis in Alzheimer's disease
    • Murialdo G, Nobili F, Rollero A, et al. Hippocampal perfusion and pituitary-adrenal axis in Alzheimer's disease. Neuropsychobiology 2000;42:51-57.
    • (2000) Neuropsychobiology , vol.42 , pp. 51-57
    • Murialdo, G.1    Nobili, F.2    Rollero, A.3
  • 7
    • 0023188288 scopus 로고
    • Dehydroepiandrosterone and its sulfate derivative reduce neuronal death and enhance astrocytic differentiation in brain cell cultures
    • Bologa L, Sharma J, Roberts E. Dehydroepiandrosterone and its sulfate derivative reduce neuronal death and enhance astrocytic differentiation in brain cell cultures. J Neurosci Res 1987;17:225-234.
    • (1987) J Neurosci Res , vol.17 , pp. 225-234
    • Bologa, L.1    Sharma, J.2    Roberts, E.3
  • 8
    • 0032539540 scopus 로고    scopus 로고
    • Dehydroepiandrosterone (DHEA) and DHEA-sulfate (DHEAS) protect hippocampal neurons against excitatory amino acid-induced neurotoxicity
    • Kimonides VG, Khatibi NH, Svendsen CN, Sofroniew MV, Herbert J. Dehydroepiandrosterone (DHEA) and DHEA-sulfate (DHEAS) protect hippocampal neurons against excitatory amino acid-induced neurotoxicity. Proc Natl Acad Sci USA 1998;95:1852-1857.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 1852-1857
    • Kimonides, V.G.1    Khatibi, N.H.2    Svendsen, C.N.3    Sofroniew, M.V.4    Herbert, J.5
  • 9
    • 0033586349 scopus 로고    scopus 로고
    • Dehydroepiandrosterone (DHEA) protects hippocampal cells from oxidative stress-induced damage
    • Bastianetto S, Ramassamy C, Poirier J, Quirion R. Dehydroepiandrosterone (DHEA) protects hippocampal cells from oxidative stress-induced damage. Brain Res Mol Brain Res 1999;66:35-41.
    • (1999) Brain Res Mol Brain Res , vol.66 , pp. 35-41
    • Bastianetto, S.1    Ramassamy, C.2    Poirier, J.3    Quirion, R.4
  • 10
    • 0031816232 scopus 로고    scopus 로고
    • The actions of exogenous dehydroepiandrosterone in experimental animals and humans
    • Svec F, Porter JR. The actions of exogenous dehydroepiandrosterone in experimental animals and humans. Proc Soc Exp Biol Med 1998;218:174-191.
    • (1998) Proc Soc Exp Biol Med , vol.218 , pp. 174-191
    • Svec, F.1    Porter, J.R.2
  • 11
    • 0023896577 scopus 로고
    • Dehydroepiandrosterone sulfate improves memory in aging mice
    • Flood JF, Roberts E. Dehydroepiandrosterone sulfate improves memory in aging mice. Brain Res 1988;448:178-181.
    • (1988) Brain Res , vol.448 , pp. 178-181
    • Flood, J.F.1    Roberts, E.2
  • 12
    • 22844457284 scopus 로고    scopus 로고
    • The Role of dehydroepiandrosterone (DHEA) in psychiatry
    • Wolkowitz OM, Brizendine L, Reus VI. The Role of dehydroepiandrosterone (DHEA) in psychiatry. Psychiatr Ann 2000;30:123-128.
    • (2000) Psychiatr Ann , vol.30 , pp. 123-128
    • Wolkowitz, O.M.1    Brizendine, L.2    Reus, V.I.3
  • 14
    • 0035235408 scopus 로고    scopus 로고
    • Dehydroepiandrosterone (DHEA) supplementation for cognitive function
    • Oxford: Update Software
    • Huppert FA, Van Niekerk JK. Dehydroepiandrosterone (DHEA) supplementation for cognitive function (Cochrane Review). The Cochrane Library. Oxford: Update Software, 2001.
    • (2001) The Cochrane Library
    • Huppert, F.A.1    Van Niekerk, J.K.2
  • 15
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
    • McKhann G, Drachman D, Folstein M, et al. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984;34:939-944.
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3
  • 16
    • 0018887732 scopus 로고
    • Pathological verification of ischemic score in differentiation of dementias
    • Rosen WG, Terry RD, Fuld PA, Katzman R, Peck A. Pathological verification of ischemic score in differentiation of dementias. Ann Neurol 1980;7:486-488.
    • (1980) Ann Neurol , vol.7 , pp. 486-488
    • Rosen, W.G.1    Terry, R.D.2    Fuld, P.A.3    Katzman, R.4    Peck, A.5
  • 17
    • 0016823810 scopus 로고
    • "Mini-mental state." A practical method for grading the cognitive state of patients for the clinician
    • Folstein MF, Folstein SE, McHugh PR. "Mini-mental state." A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975;12:189-198.
    • (1975) J Psychiatr Res , vol.12 , pp. 189-198
    • Folstein, M.F.1    Folstein, S.E.2    McHugh, P.R.3
  • 18
    • 0030963198 scopus 로고    scopus 로고
    • Cognitive screening instruments in neuropsychiatry: A report of the Committee on Research of the American Neuropsychiatric Association
    • Malloy PF, Cummings JL, Coffey CE, et al. Cognitive screening instruments in neuropsychiatry: a report of the Committee on Research of the American Neuropsychiatric Association. J Neuropsychiatry Clin Neurosci 1997;9:189-197.
    • (1997) J Neuropsychiatry Clin Neurosci , vol.9 , pp. 189-197
    • Malloy, P.F.1    Cummings, J.L.2    Coffey, C.E.3
  • 19
    • 0032938476 scopus 로고    scopus 로고
    • Double-blind treatment of major depression with dehydroepiandrosterone (DHEA)
    • Wolkowitz OM, Reus VI, Keebler A, et al. Double-blind treatment of major depression with dehydroepiandrosterone (DHEA). Am J Psychiatry 1999;156:646-649.
    • (1999) Am J Psychiatry , vol.156 , pp. 646-649
    • Wolkowitz, O.M.1    Reus, V.I.2    Keebler, A.3
  • 21
    • 0021520020 scopus 로고
    • A new rating scale for Alzheimer's disease
    • Rosen WG, Mohs R, Davis KL. A new rating scale for Alzheimer's disease. Am J Psychiatry 1984;141:1356-1364.
    • (1984) Am J Psychiatry , vol.141 , pp. 1356-1364
    • Rosen, W.G.1    Mohs, R.2    Davis, K.L.3
  • 22
    • 0030862602 scopus 로고    scopus 로고
    • Validity and reliability of the Alzheimer's Disease Cooperative Study-Clinical Global Impression of Change
    • The Alzheimer's Disease Cooperative Study
    • Schneider LS, Olin JT, Doody RS, et al. Validity and reliability of the Alzheimer's Disease Cooperative Study-Clinical Global Impression of Change. The Alzheimer's Disease Cooperative Study. Alzheimer Dis Assoc Disord 1997;11:S22-S32.
    • (1997) Alzheimer Dis Assoc Disord , vol.11
    • Schneider, L.S.1    Olin, J.T.2    Doody, R.S.3
  • 24
    • 0032055231 scopus 로고    scopus 로고
    • Longitudinal changes in dehydroepiandrosterone concentrations in men and women
    • Nafziger AN, Bowlin SJ, Jenkins PL, Pearson TA. Longitudinal changes in dehydroepiandrosterone concentrations in men and women. J Lab Clin Med 1998;131:316-323.
    • (1998) J Lab Clin Med , vol.131 , pp. 316-323
    • Nafziger, A.N.1    Bowlin, S.J.2    Jenkins, P.L.3    Pearson, T.A.4
  • 25
    • 0003525258 scopus 로고
    • Rockville, MD: US Food and Drug Administration, Center for Drug Evaluation and Research
    • US Department of Health Education and Welfare. Coding symbols for thesaurus of adverse reaction terms (COSTART). Rockville, MD: US Food and Drug Administration, Center for Drug Evaluation and Research, 1995.
    • (1995) Coding Symbols for Thesaurus of Adverse Reaction Terms (COSTART)
  • 26
    • 85038457062 scopus 로고    scopus 로고
    • Dehydroepiandrosterone administration in demented patients and non-demented elderly volunteers
    • Abstract
    • Dukoff R, Molchan S, Putnam K, Lai J, Sunderland T. Dehydroepiandrosterone administration in demented patients and non-demented elderly volunteers. Biol Psychiatry 1998;43:55S. Abstract.
    • (1998) Biol Psychiatry , vol.43
    • Dukoff, R.1    Molchan, S.2    Putnam, K.3    Lai, J.4    Sunderland, T.5
  • 27
    • 0032921563 scopus 로고    scopus 로고
    • The effect of dehydroepiandrosterone sulfate administration to patients with multi-infarct dementia
    • Azuma T, Nagai Y, Saito T, Funauchi M, Matsubara T, Sakoda S. The effect of dehydroepiandrosterone sulfate administration to patients with multi-infarct dementia. J Neurol Sci 1999;162:69-73.
    • (1999) J Neurol Sci , vol.162 , pp. 69-73
    • Azuma, T.1    Nagai, Y.2    Saito, T.3    Funauchi, M.4    Matsubara, T.5    Sakoda, S.6
  • 28
    • 0012915112 scopus 로고    scopus 로고
    • Dehydroepiandrosterone. Uses and abuses
    • Kelley WN, Harris Jr ED, Ruddy S, Sledge CB, eds. Philadelphia: WB Saunders
    • van Vollenhoven RF. Dehydroepiandrosterone. Uses and abuses. In: Kelley WN, Harris Jr ED, Ruddy S, Sledge CB, eds. Textbook of rheumatology. Philadelphia: WB Saunders, 1997;1-25.
    • (1997) Textbook of Rheumatology , pp. 1-25
    • Van Vollenhoven, R.F.1
  • 29
    • 0032481568 scopus 로고    scopus 로고
    • Estrogen therapy in postmenopausal women: Effects on cognitive function and dementia
    • Yaffe K, Sawaya G, Lieberburg I, Grady D. Estrogen therapy in postmenopausal women: effects on cognitive function and dementia. JAMA 1998;279:688-695.
    • (1998) JAMA , vol.279 , pp. 688-695
    • Yaffe, K.1    Sawaya, G.2    Lieberburg, I.3    Grady, D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.