Distinct neurochemical mechanisms are activated following administration of different P2X receptor agonists into the hindpaw of a rat

Brain Research

Volumn 965, Issue 1-2, 2003, Pages 187-193

  Wismer, Carol T ^a   Faltynek, Connie R ^a   Jarvis, Michael F ^a   McGaraughty, Steve ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

Adenosine triphosphate (ATP); NK 1; NMDA; Nocifensive behavior; P2X receptor; Resiniferatoxin

Indexed keywords

ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE DERIVATIVE; ALPHA,BETA METHYLENEADENOSINE TRIPHOSPHATE; CAPSAICIN; DIZOCILPINE; FORMALDEHYDE; L 703 606; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NEUROKININ 1 RECEPTOR ANTAGONIST; PURINE P2X RECEPTOR; PURINERGIC RECEPTOR STIMULATING AGENT; RESINIFERATOXIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; HINDLIMB; MALE; NOCICEPTION; NONHUMAN; PREMEDICATION; PRIORITY JOURNAL; RAT;

EID: 0037424553     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(02)04193-8     Document Type: Article

References (39)

1. Bianchi B.R., Lynch K.J., Touma E., Niforatos W., Burgard E.C., Alexander K.M., Park H.S., Yu H., Metzger R., Kowaluk E., Jarvis M.F., van Biesen T. Pharmacological characterization of recombinant human and rat P2X receptor subtypes. Eur. J. Pharmacol. 376:1999;127-138.
2. Bland-Ward P.A., Humphrey P.P. Acute nociception mediated by hindpaw P2X receptor activation in the rat. Br. J. Pharmacol. 122:1997;365-371.
3. Burnstock G. A unifying purinergic hypothesis for the initiation of pain. Lancet. 347:1996;1604-1605.
4. Burnstock G., Wood J.N. Purinergic receptors: their role in nociception and primary afferent neurotransmission. Curr. Opin. Neurobiol. 6:1996;526-532.
5. Chen C.C., Akopian A.N., Sivilotti L., Colquhoun D., Burnstock G., Wood J.N. A P2X purinoceptor expressed by a subset of sensory neurons. Nature. 377:1995;428-431.
6. Cockayne D.A., Hamilton S.G., Zhu Q.M., Dunn P.M., Zhong Y., Novakovic S., Malmberg A.B., Cain G., Berson A., Kassotakis L., Hedley L., Lachnit W.G., Burnstock G., McMahon S.B., Ford A.P. Urinary bladder hyporeflexia and reduced pain-related behaviour in P2X3-deficient mice. Nature. 407:2000;1011-1015.
7. Coderre T.J. Potent analgesia induced in rats by combined action at PCP and polyamine recognition sites of the NMDA receptor complex. Eur. J. Neurosci. 5:1993;390-393.
8. Collo G., North R.A., Kawashima E., Merlo-Pich E., Neidhart S., Surprenant A., Buell G. Cloning of P2X5 and P2X6 receptors and the distribution and properties of an extended family of ATP-gated ion channels. J. Neurosci. 16:1996;2495-2507.
9. Cook S.P., McCleskey E.W. Cell damage excites nociceptors through release of cytosolic ATP. Pain. 95:2002;41-47.
10. Deuchars S.A., Atkinson L., Brooke R.E., Musa H., Milligan C.J., Batten T.F., Buckley N.J., Parson S.H., Deuchars J. Neuronal P2X7 receptors are targeted to presynaptic terminals in the central and peripheral nervous systems. J. Neurosci. 21:2001;7143-7152.
11. Gamse R. Capsaicin and nociception in the rat and mouse. Possible role of substance P. Naunyn Schmiedebergs Arch. Pharmacol. 320:1982;205-216.
12. Guo A., Vulchanova L., Wang J., Li X., Elde R. Immunocytochemical localization of the vanilloid receptor 1 (VR1): relationship to neuropeptides, the P2X3 purinoceptor and IB4 binding sites. Eur. J. Neurosci. 11:1999;946-958.
13. Hamilton S.G., Wade A., McMahon S.B. The effects of inflammation and inflammatory mediators on nociceptive behaviour induced by ATP analogues in the rat. Br. J. Pharmacol. 126:1999;326-332.
14. Henry J.L., Yashpal K., Pitcher G.M., Chabot J., Coderre T.J. Evidence for tonic activation of NK-1 receptors during the second phase of the formalin test in the rat. J. Neurosci. 19:1999;6588-6598.
15. Hiura A., Ishizuka H. Changes in features of degenerating primary sensory neurons with time after capsaicin treatment. Acta Neuropathol. (Berl.). 78:1989;35-46.
16. 3 antisense oligonucleotide treatment in chronic inflammatory and neuropathic pain states in rats. Pain. 99:2002;11-19.
17. Jacobson K.A., Jarvis M.F., Williams M. Perspective: purine and pyrimidine (P2) receptors as drug targets. J. Med. Chem. 45:2002;4057-4093.
18. Jarvis M.F., Wismer C.T., Schweitzer E., Yu H., van Biesen T., Lynch K.J., Burgard E.C., Kowaluk E.A. Modulation of BzATP and formalin induced nociception: attenuation by the P2X receptor antagonist, TNP-ATP and enhancement by the P2X(3) allosteric modulator, cibacron blue. Br. J. Pharmacol. 132:2001;259-269.
19. Kato A., Ohkubo T., Kitamura K. Algogen-specific pain processing in mouse spinal cord: differential involvement of voltage-dependent Ca(2+) channels in synaptic transmission. Br. J. Pharmacol. 135:2002;1336-1342.
20. S. Koizumi, M. Tsuda, Y. Shigemoto-Mogami, T. Obama, K. Inoue, Involvement of P2Y receptors in ATP-evoked calcium signaling in capsaicin-sensitive rat dorsal root ganglion neurons, Soc. Neurosci. Abstr. (2001) 158.7.
21. Lewis C., Neidhart S., Holy C., North R.A., Buell G., Surprenant A. Coexpression of P2X2 and P2X3 receptor subunits can account for ATP-gated currents in sensory neurons. Nature. 377:1995;432-435.
22. Nakatsuka T., Furue H., Yoshimura M., Gu J.G. Activation of central terminal vanilloid receptor-1 receptors and alpha beta-methylene-ATP-sensitive P2X receptors reveals a converged synaptic activity onto the deep dorsal horn neurons of the spinal cord. J. Neurosci. 22:2002;1228-1237.
23. Peterson M.A., Basbaum A.I., Abbadie C., Rohde D.S., McKay W.R., Taylor B.K. The differential contribution of capsaicin-sensitive afferents to behavioral and cardiovascular measures of brief and persistent nociception and to Fos expression in the formalin test. Brain Res. 755:1997;9-16.
24. Ralevic V., Burnstock G. Receptors for purines and pyrimidines. Pharmacol. Rev. 50:1998;413-492.
25. Sakurada T., Katsumata K., Yogo H., Tan-No K., Sakurada S., Kisara K. Antinociception induced by CP 96,345, a non-peptide NK-1 receptor antagonist, in the mouse formalin and capsaicin tests. Neurosci. Lett. 151:1993;142-145.
26. Sakurada T., Wako K., Sugiyama A., Sakurada C., Tan-No K., Kisara K. Involvement of spinal NMDA receptors in capsaicin-induced nociception. Pharmacol. Biochem. Behav. 59:1998;339-345.
27. Souslova V., Cesare P., Ding Y., Akopian A.N., Stanfa L., Suzuki R., Carpenter K., Dickenson A., Boyce S., Hill R., Nebenuis-Oosthuizen D., Smith A.J., Kidd E.J., Wood J.N. Warm-coding deficits and aberrant inflammatory pain in mice lacking P2X3 receptors. Nature. 407:2000;1015-1017.
28. Szallasi A., Joo F., Blumberg P.M. Duration of desensitization and ultrastructural changes in dorsal root ganglia in rats treated with resiniferatoxin, an ultrapotent capsaicin analog. Brain Res. 503:1989;68-72.
29. M. Tsuda, Y. Mogami, S. Koizumi, K. Inoue, Peripheral and spinal mechanisms of α,β-methylene ATP-induced mechanical allodynia in rats, Soc. Neurosci. Abstr. 1 (2001) 158.11.
30. Tsuda M., Koizumi S., Kita A., Shigemoto Y., Ueno S., Inoue K. Mechanical allodynia caused by intraplantar injection of P2X receptor agonist in rats: involvement of heteromeric P2X2/3 receptor signaling in capsaicin-insensitive primary afferent neurons. J. Neurosci. 20:2000;RC90.
31. Ueda H., Matsunaga S., Inoue M., Yamamoto Y., Hazato T. Complete inhibition of purinoceptor agonist-induced nociception by spinorphin, but not by morphine. Peptides. 21:2000;1215-1221.
32. Ueno S., Tsuda M., Iwanaga T., Inoue K. Cell type-specific ATP-activated responses in rat dorsal root ganglion neurons. Br. J. Pharmacol. 126:1999;429-436.
33. Vieira C., Evangelista S., Cirillo R., Terracciano R., Lippi A., Maggi C.A., Manzini S. Antinociceptive activity of ricinoleic acid, a capsaicin-like compound devoid of pungent properties. Eur. J. Pharmacol. 407:2000;109-116.
34. Vulchanova L., Riedl M.S., Shuster S.J., Buell G., Surprenant A., North R.A., Elde R. Immunohistochemical study of the P2X2 and P2X3 receptor subunits in rat and monkey sensory neurons and their central terminals. Neuropharmacology. 36:1997;1229-1242.
35. 2+ modulation of ATP-responses at recombinant P2X2 receptors and its dependence on extracellular pH. Br. J. Pharmacol. 123:1998;1214-1220.
36. Xiang Z., Bo X., Burnstock G. Localization of ATP-gated P2X receptor immunoreactivity in rat sensory and sympathetic ganglia. Neurosci. Lett. 256:1998;105-108.
37. Xu G.Y., Huang L.Y. Peripheral inflammation sensitizes P2X receptor-mediated responses in rat dorsal root ganglion neurons. J. Neurosci. 22:2002;93-102.
38. Yoshida K., Nakagawa T., Kaneko S., Akaike A., Satoh M. Adenosine 5′-triphosphate inhibits slow depolarization induced by repetitive dorsal root stimulation via P2Y purinoceptors in substantia gelatinosa neurons of the adult rat spinal cord slices with the dorsal root attached. Neurosci. Lett. 320:2002;121-124.
39. Zhong Y., Dunn P.M., Bardini M., Ford A.P., Cockayne D.A., Burnstock G. Changes in P2X receptor responses of sensory neurons from P2X3-deficient mice. Eur. J. Neurosci. 14:2001;1784-1792.