GDP affinity and order state of the catalytic site are critical for function of xanthine nucleotide-selective Gαs proteins

Journal of Biological Chemistry

Volumn 278, Issue 10, 2003, Pages 7822-7828

  Gille, Andreas ^a   Wenzel Seifert, Katharina ^a   Doughty, Michael B ^a,b   Seifert, Roland ^a  

^a UNIVERSITY OF KANSAS   (United States)

^b SOUTHEASTERN LOUISIANA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; MUTAGENESIS; PHOSPHATES; PROTEINS;

BINDING PROTEINS;

BIOCHEMISTRY;

ADENOSINE 5' (GAMMA THIO)TRIPHOSPHATE DERIVATIVE; ADENYLYLIMIDODIPHOSPHATE; ASPARAGINE; ASPARTIC ACID; BETA 2 ADRENERGIC RECEPTOR; GLUTAMINE; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE DIPHOSPHATE; GUANYLYLIMIDODIPHOSPHATE; LEUCINE; NUCLEOSIDE; UNCLASSIFIED DRUG; XANTHINE; XANTHOSINE 5' (BETA,GAMMA IMIDO)TRIPHOSPHATE; NUCLEOTIDE; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN;

ARTICLE; BINDING AFFINITY; CATALYSIS; ENZYME ACTIVITY; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FUNCTION; ANIMAL; ARMYWORM; BINDING SITE; ENZYME ACTIVE SITE; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY;

ANIMALS; BINDING SITES; CATALYTIC DOMAIN; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; GUANOSINE DIPHOSPHATE; NUCLEOTIDES; PHOSPHORYLATION; SPODOPTERA; XANTHINE;

EID: 0037424399     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M210162200     Document Type: Article

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