High concentrations of viscogens decrease the protein folding rate constant by prematurely collapsing the coil

Journal of Molecular Biology

Volumn 326, Issue 1, 2003, Pages 263-271

  Silow, Maria ^a   Oliveberg, Mikael ^a  

^a UMEÅ UNIVERSITY   (Sweden)

Author keywords

Denatured state; Folding energy landscape; Protein engineering; Protein folding; Viscosity

Indexed keywords

CHYMOTRYPSIN INHIBITOR 2; ETHYLENE GLYCOL; MACROGOL; MACROGOL 200; MACROGOL 400; PROTEIN; SOLVENT; STABILIZING AGENT; SUCROSE; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION (PARAMETERS); OSMOLYTE; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN STABILITY; VISCOSITY;

EID: 0037423748     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2836(02)01331-1     Document Type: Article

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