Insulin-like growth factor-1 exerts Ca2+-dependent positive inotropic effects in failing human myocardium

Circulation Research

Volumn 92, Issue 2, 2003, Pages 169-176

  Von Lewinski, Dirk ^a   Voß, Kerstin ^a   Hülsmann, Swen ^a   Kögler, Harald ^a   Pieske, Burkert ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

Ca2+ handling; Functional effects; Heart failure; Human myocardium; Insulin like growth factor 1

Indexed keywords

2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; 2 [2 [4 (4 NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA METHANESULFONATE; CALCIUM CHANNEL L TYPE; CALCIUM ION; CYCLIC AMP; DILTIAZEM; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE C; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; WORTMANNIN;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; HEART FAILURE; HUMAN; HUMAN TISSUE; INOTROPISM; PRIORITY JOURNAL; SARCOPLASMIC RETICULUM; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, L-TYPE; CARDIOTONIC AGENTS; CELLS, CULTURED; CYCLIC AMP; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; HEART FAILURE, CONGESTIVE; HUMANS; INSULIN-LIKE GROWTH FACTOR I; ION TRANSPORT; ISOMETRIC CONTRACTION; MYOCARDIAL CONTRACTION; MYOCARDIUM; MYOCYTES, CARDIAC; PATCH-CLAMP TECHNIQUES; SARCOLEMMA; SARCOPLASMIC RETICULUM; SIGNAL TRANSDUCTION; SODIUM-HYDROGEN ANTIPORTER;

EID: 0037423666     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000051885.70159.12     Document Type: Article

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