Pressure treatment of tailspike aggregates rapidly produces on-pathway folding intermediates

Biotechnology and Bioengineering

Volumn 82, Issue 5, 2003, Pages 595-604

  Lefebvre, Brian G ^a   Robinson, Anne Skaja ^a  

^a University of Delaware   (United States)

Author keywords

Aggregation; Chaotrope; Hydrostatic pressure; P22 tailspike; Protein folding kinetics; Protein stability

Indexed keywords

ELECTROPHORESIS; FLUORESCENCE; MATHEMATICAL MODELS; PROTEINS; SIZE EXCLUSION CHROMATOGRAPHY; THERMAL EFFECTS;

TAILSPIKE AGGREGATES;

AGGLOMERATION;

PROTEIN; TRYPTOPHAN;

ARTICLE; BINDING COMPETITION; CIRCULAR DICHROISM; DENATURATION; DILUTION; DISSOCIATION; FLUORESCENCE; GEL PERMEATION CHROMATOGRAPHY; HYPERBARISM; INCUBATION TIME; MATHEMATICAL ANALYSIS; POLYACRYLAMIDE GEL ELECTROPHORESIS; POPULATION RESEARCH; PRESSURE MEASUREMENT; PROTEIN AGGREGATION; PROTEIN FOLDING; SPIKE WAVE; STRUCTURE ANALYSIS; TAILSPIKE; TEMPERATURE MEASUREMENT;

GLYCOSIDE HYDROLASES; MACROMOLECULAR SUBSTANCES; POLYMERS; PRESSURE; PROTEIN BINDING; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; TEMPERATURE; VIRAL TAIL PROTEINS;

EID: 0037420910     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/bit.10607     Document Type: Article

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