A BRCA2 germ-line mutation in familial pancreatic carcinoma [2]

International Journal of Cancer

Volumn 91, Issue 5, 2001, Pages 742-744

  White, Karen ^a,b   Held, Karsten R ^a,c   Weber, Bernhard H F ^b,c  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b Arndt and Partner   (Germany)

^c UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA2 PROTEIN;

FAMILIAL CANCER; GENE DELETION; GENE MUTATION; GENETIC COUNSELING; HUMAN; LETTER; PANCREAS CARCINOMA; PRIORITY JOURNAL;

EID: 0035283898     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0215(200002)9999:9999<::AID-IJC1116>3.0.CO;2-L     Document Type: Letter

References (24)

1. Identification of the breast cancer susceptibility gene BRCA2
2. The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds
3. Identification by representational difference analysis of a homozygous deletion in pancreatic carcinoma that lies within the BRCA2 region
4. Mutation analysis of the BRCA2 gene in 49 site-specific breast cancer families
5. A single BRCA2 mutation in male and female breast cancer families from Iceland with varied cancer phenotypes
6. BRCA2 in American families with four or more cases of breast or ovarian cancer: Recurrent and novel mutations, variable expression, penetrance, and the possibility of families whose cancer is not attributable to BRCA1 or BRCA2
7. Cancer risks in BRCA2 mutation carriers
8. Germline BRCA2 gene mutations in patients with apparently sporadic pancreatic carcinomas
9. Germline BRCA2 6174delT mutations in Ashkenazi Jewish pancreatic cancer patients
10. Inherited predisposition to pancreatic adenocarcinoma: Role of family history and germ-line p16, BRCA1, and BRCA2 mutations
11. A somatic truncating mutation in BRCA2 in a sporadic breast tumor
12. Familial pancreatic adenocarcinoma in three generations. A case report and a review of the literature
13. Genetics and pancreatic cancer
14. Medical genetic study of eight pancreatic cancer-prone families
15. Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes
16. Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma
17. K-ras and p53 gene mutations in pancreatic cancer: Ductal and nonductal tumors progress through different genetic lesions
18. p53 mutations in pancreatic carcinoma and evidence of common involvement of homocopolymer tracts in DNA microdeletions
19. DPC4 gene in various tumor types
20. Human mitogen-activated protein kinase kinase 4 as a candidate tumor suppressor
21. Pancreatic adenocarcinomas with DNA replication errors (RER+) are associated with wild-type K-ras and characteristic histopathology. Poor differentiation, a syncytial growth pattern, and pushing borders suggest RER+
22. Germline and somatic mutations of the STK11/LKB1 Peutz-Jeghers gene in pancreatic and biliary cancers
23. Brief report: A familial syndrome of pancreatic cancer and melanoma with a mutation in the CDKN2 tumor-suppressor gene
24. Novel germline p16(INK4) allele (Asp145Cys) in a family with multiple pancreatic carcinomas. Mutations in brief no. 148