Drosophila Crumbs is a positional cue in photoreceptor adherens junctions and rhabdomeres

Nature

Volumn 416, Issue 6877, 2002, Pages 178-182

  Izaddoost, Shayan ^a   Nam, Sang Chul ^a   Bhat, Manzoor A ^a   Bellen, Hugo J ^a   Choi, Kwang Wook ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MUTAGENESIS; PHOTOSENSITIVITY; PROTEINS;

PHOTORECEPTOR ADHERENCE JUNCTIONS;

GENETIC ENGINEERING;

AMINO ACID; ERYTHROCYTE BAND 4.1 PROTEIN;

BIOCHEMISTRY; VISION;

ANIMAL TISSUE; ARTICLE; ASSOCIATION; BINDING SITE; CELL JUNCTION; CELL POLARITY; DROSOPHILA; IMMUNOHISTOCHEMISTRY; LEBER CONGENITAL AMAUROSIS; MUTATION; NONHUMAN; PHOTORECEPTOR; PRIORITY JOURNAL; RETINA; RETINITIS PIGMENTOSA; TRANSMISSION ELECTRON MICROSCOPY;

NON-PROGRAMMATIC;

ADHERENS JUNCTIONS; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CELL MEMBRANE; CELL POLARITY; CONSERVED SEQUENCE; CUES; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; EYE; EYE PROTEINS; HUMANS; INSECT PROTEINS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; MORPHOGENESIS; MUTATION; NERVE TISSUE PROTEINS; PHENOTYPE; PHOTORECEPTORS, INVERTEBRATE; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT;

ANIMALIA;

EID: 0037075546     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature720     Document Type: Article

References (23)

1. crumbs encodes an EGF-like protein expressed on apical membranes of Drosophila epithelial cells and required for organization of epithelia
2. Expression of crumbs confers apical character on plasma membrane domains of ectodermal epithelia of Drosophila
3. A conserved motif in the cytoplasmic domain of Drosophila Crumbs is required for DE-cadherin localisation and zonula adherens formation
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5. Mutations in a human homologue of Drosophila crumbs cause retinitis pigmentosa (RP12)
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