Arresting and releasing Staphylococcal α-hemolysin at intermediate stages of pore formation by engineered disulfide bonds

Protein Science

Volumn 12, Issue 5, 2003, Pages 997-1006

  Kawate, Toshimitsu ^a   Gouaux, Eric ^a  

^a Columbia University ^*  (United States)

Author keywords

Assembly intermediate; Disulfide bonds; Double cysteine mutants; Pore forming toxin; Staphylococcal hemolysin

Indexed keywords

HEMOLYSIN;

ARTICLE; CHANNEL GATING; CONFORMATIONAL TRANSITION; CROSS LINKING; DISULFIDE BOND; MOLECULAR MECHANICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN ENGINEERING; STAPHYLOCOCCUS AUREUS;

AMINO ACID SUBSTITUTION; BACTERIAL TOXINS; CELL MEMBRANE PERMEABILITY; CYSTEINE; DIMERIZATION; DISULFIDES; ERYTHROCYTES; HEMOLYSIN PROTEINS; HEMOLYSIS; MUTAGENESIS, SITE-DIRECTED; OXIDATION-REDUCTION; PHOSPHATIDYLCHOLINES; POROSITY; STAPHYLOCOCCUS AUREUS;

INSERTION SEQUENCES; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS;

EID: 0037407011     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.0231203     Document Type: Article

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