Chemokine sequestration by viral chemoreceptors as a novel viral escape strategy: Withdrawal of chemokines from the environment of cytomegalovirus- infected cells

Journal of Experimental Medicine

Volumn 188, Issue 5, 1998, Pages 855-866

  Bodaghi, Bahram ^a   Jones, Thomas R ^b   Zipeto, Donato ^a   Vita, Claudio ^c   Sun, Lei ^b   Laurent, Lysiane ^a   Arenzana Seisdedos, Fernando ^a   Virelizier, Jean Louis ^a   Michelson, Susan ^a  

^a INSTITUT PASTEUR   (France)

^b PFIZER INC   (United States)

^c CEA SACLAY   (France)

Author keywords

Chemokine receptors; Human cytomegalovirus; RANTES; Sequestration monocyte chemoattractant protein 1

Indexed keywords

CHEMOKINE RECEPTOR; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 2; MONOCYTE CHEMOTACTIC PROTEIN 3; RANTES;

ARTICLE; BINDING COMPETITION; CHEMICAL BINDING; CONTROLLED STUDY; CYTOMEGALOVIRUS; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; SEQUENCE HOMOLOGY; VIRUS MUTATION;

BINDING SITES; CELLS, CULTURED; CHEMOKINE CCL2; CHEMOKINES, CC; CULTURE MEDIA; CYTOMEGALOVIRUS; FIBROBLASTS; GENE DELETION; HUMANS; INTRACELLULAR FLUID; RANTES; RECEPTORS, CHEMOKINE; RECEPTORS, VIRUS; TUMOR NECROSIS FACTOR-ALPHA; VIRUS REPLICATION;

EID: 0032494168     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.188.5.855     Document Type: Article

References (53)

1. Loetscher, P., M. Seitz, M. Baggiolini, and B. Moser. 1996. Interleukin 2 regulates CC chemokine receptor expression and chemotactic responsiveness in T lymphocytes. J. Exp. Med. 184:569-577.
2. Davis-Poynter, N.J., and H.E. Farrell. 1996. Masters of deception: a review of herpesvirus immune evasion strategies. Immunol. Cell. Biol. 74:513-522.
3. Moore, P.S., C. BoshofF, R.A. Weiss, and Y. Chang. 1996. Molecular mimicry of human cytokine and cytokine response pathway genes by KSHV. Science. 274:1739-1744.
4. Murphy, P.M. 1994. Molecular piracy of chemokine receptors by herpesviruses. Infect. Agents Dis. 3:137-154.
5. Smith, G.L. 1996. Virus proteins that bind cytokines, chemokines or interferons. Curr. Opin. Immunol. 8:467-471.
6. Smith, G.L. 1994. Viral strategies for evasion of the host response to infection. Trends Microbiol. 2:81-88.
7. Roizman, B.H. 1996. Herpesviridae. In Virology. 3rd. ed. B.N. Fields, D.M. Knipe, and P.M. Howley, editors. Lippincott-Raven Publishers, Philadelphia, PA. 2221-2230.
8. McGeoch, D.J., S. Cook, A. Dolan, F.E. Jamieson, and E.A. Telford. 1995. Molecular phylogeny and evolutionary time-scale for the family of mammalian herpesviruses. J. Mol. Biol. 247:443-458.
9. Hendrix, M.G.R., E. Beuken, R.L. Slobbe, and C.A. Bruggeman. 1996. Detection and sequence analysis of the major immediate early and pp150 gene of latent human cytomegalovirus in spleen, liver and kidney tissues of trauma victims. J. Med. Virol. 50:193-197.
10. Myerson, D., R.C. Hackman, J.A. Nelson, D.C. Ward, and J.K. McDougall. 1984. Widespread presence of histologically occult cytomegalovirus. Hum. Pathol. 15:430-439.
11. Toorkey, C.B., and D.R. Carrigan. 1989. Immunohistochemical detection of an immediate early antigen of human cytomegalovirus in normal tissues. J. Infect. Dis. 160:741-751.
12. Furukawa, T., E. Hornberger, S. Sakuma, and S.A. Plotkin. 1975. Demonstration of immunoglobulin G receptors induced by human cytomegalovirus. J. Clin. Microbiol. 2:332-336.
13. MacCormac, L.P., and J.E. Grundy. 1996. Human cytomegalovirus induces an Fc gamma receptor (FcγR) in endothelial cells and fibroblasts that is distinct from the human cellular FcγRs. J. Infect. Dis. 174:1151-1161.
14. Stannard, L.M., and D.R. Hardie. 1991. An Fc receptor for human immunoglobulin G is located within the tegument of human cytomegalovirus. J. Virol. 65:3411-3415.
15. Xu, B., T. Murayama, K. Ishida, and T. Furukawa. 1989. Characterization of IgG Fc receptors induced by human cytomegalovirus. J. Gen. Virol. 70:893-900.
16. Spiller, O.B., B.P. Morgan, F. Tufaro, and D.V. Devine. 1996. Altered expression of host-encoded complement regulators on human cytomegalovirus-infected cells. Eur. J. Immunol. 26:1532-1538.
17. Spear, G.T., N.S. Lurain, C.J. Parker, M. Ghassemi, G.H. Payne, and M. Saifuddin. 1995. Host cell-derived complement control proteins CD55 and CD59 are incorporated into the virions of two unrelated enveloped viruses. Human T cell leukemia/lymphoma virus type 1 (HTLV-I) and human cytomegalovirus (HCMV). J. Immunol. 155:4376-4381.
18. Jones, T.R., L.K. Hanson, L. Sun, J.S. Slater, R.M. Stenberg, and A.E. Campbell. 1995. Multiple independent loci within the human cytomegalovirus unique short region down-regulate expression of major histocompatibility complex class I heavy chains. J. Virol. 69:4830-4841.
19. Jones, T.R., E. Wiertz, L. Sun, K.N. Fish, J.A. Nelson, and H.L. Ploegh. 1996. Human cytomegalovirus US3 impairs transport and maturation of major histocompatibility complex class I heavy chains. Prof. Natl. Acad. Sci. USA. 93: 11327-11333.
20. Jones, T.R., and L. Sun. 1997. Human cytomegalovirus US2 destabilizes major histocompatibility complex class I heavy chains. J. Virol. 71:2970-2979.
21. Wiertz, E., D. Tortorella, M. Bogyo, J. Yu, W. Mothes, T.R. Jones, T.A. Rapoport, and H.L. Ploegh. 1996. Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction. Nature. 384: 432-438.
22. Ahn, K., A. Gruhler, B. Galocha, T.R. Jones, E. Wiertz, H.L. Ploegh, P.A. Peterson, Y. Yang, and K. Fruh. 1997. The ER-luminal domain of the HCMV glycoprotein US6 inhibits peptide translocation by TAP. Immunity. 6:613-621.
23. Wiertz, E., T.R. Jones, L. Sun, M. Bogyo, H.J. Geuze, and H.L. Ploegh. 1996. The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol. Cell. 84:769-779.
24. Cosman, D., N. Fanger, L. Borges, M. Kubin, W. Chin, L. Peterson, and M.L. Hsu. 1997. A novel immunoglobulin superfamily receptor for cellular and viral MHC class I molecules. Cell. 7:273-282.
25. Reyburn, H.T., O. Mandelboim, M. Valesgomez, D.M. Davis, L. Pazmany, and J.L. Strominger. 1997. The class I MHC homologue of human cytomegalovirus inhibits attack by natural killer cells. Nature. 386:514-517.
26. Beck, S., and B. Barrell. 1991. An HCMV reading frame which has similarity with both the V and C regions of the TCR gamma chain. DNA Seq. 2:33-38.
27. Margulies, B.J., H. Browne, and W. Gibson. 1996. Identification of the human cytomegalovirus G protein-coupled receptor homologue encoded by Ul33 in infected cells and enveloped virus particles. Virology. 225:111-125.
28. Chee, M.S., A.T. Bankier, S. Beck, R. Bohni, C.M. Brown, R. Cerny, T. Horsnell, C.A. Hutchison III, T. Kouzarides, J.A. Martignetti, et al. 1990. Analysis of the protein-coding content of the sequence of human cytomegalovirus strain AD169. Curr. Top. Microbiol. Immunol. 154:125-169.
29. Neote, K., D. DiGregorio, J.Y. Mak, R. Horuk, and T.J. Schall. 1993. Molecular cloning, functional expression, and signaling characteristics of a C-C chemokine receptor. Cell. 72:415-425.
30. Gao, J.L., and P.M. Murphy. 1994. Human cytomegalovirus open reading frame US28 encodes a functional beta chemokine receptor. J. Biol. Chem. 269:28539-28542.
31. Alcami, J., T. Barzu, and S. Michelson. 1991. Induction of an endothelial cell growth factor by human cytomegalovirus infection of fibroblasts. J. Gen. Virol. 72:2765-2770.
32. Jones, T.R., V.P. Muzithras, and Y. Gluzman. 1991. Replacement mutagenesis ot the human cytomegalovirus genome: US10 and US11 gene products are nonessential. J. Virol. 65:5860-5872.
33. Jones, T.R., and V.P. Muzithras. 1991. Fine mapping of transcripts expressed from the US6 gene family of human cytomegalovirus strain AD169. J. Virol 65:2024-2036.
34. Samanta, A.K., J.J. Oppenheim, and K. Matsushima. 1990. Interleukin 8 (monocyte-derived neutrophil chemotactic factor) dynamically regulates its own receptor expression on human neutrophils. J. Biol. Chem. 265:183-189.
35. Ylisastigui, L., J. Vizzavona, E. Drakopoulou, P. Paindivoine, C. Calvo, M. Parmentier, J.C. Gluckman, C. Vita, and A. Benjouad. 1998. Synthetic full-length RANTES and truncated RANTES inhibit human immunodeficiency virus type 1 infection of primary macrophages. AIDS. In press.
36. Jones, T.R., L. Sun, G.A. Bebernitz, V.P. Muzithras, H.J. Kim, S.H. Johnston, and E.Z. Baum. 1994. Proteolytic activity of human cytomegalovirus UL80 protease cleavage site mutants. J. Virol. 68:3742-3752.
37. Kavasaki, E.S. 1990. Amplification of RNA. In PCR Protocols: A Guide to Methods and Application. D.H. Geltand, M.A. Innis, J.J. Snisky, and T.J. White, editors. Academic Press Inc., San Diego, CA. 21-27.
38. Michelson, S., P. Dalmonte, D. Zipeto, B. Bodaghi, L. Laurent, E. Oberlin, F. Arenzana-Seisdedos, J.L. Virelizier, and M.P. Landini. 1997. Modulation of RANTES production by human cytomegalovirus infection of fibroblasts. J. Virol. 71: 6495-6500.
39. Chee, M.S., S.C. Satchwell, E. Preddie, K.M. Weston, and B.C. Barrell. 1990. Human cytomegalovirus encodes three G protein-coupled receptor homologues. Nature. 344:774-777.
40. Welch, A.R., L.M. McGregor, and W. Gibson. 1991. Cytomegalovirus homologs of cellular G protein-coupled receptor genes are transcribed. J. Virol. 65:3915-3918.
41. Baggiolini, M., B. Dewald, and B. Moser. 1994. Interleukin-8 and related chemotactic cytokines - CXC and CC chemokines. Adv. Immunol. 55:97-179.
42. Amara, A., S.L. Gall, O. Schwartz, J. Salamero, M. Montes, P. Loetscher, M. Baggiolini, J.L. Virelizier, and F. Arenzana-Seisdedos. 1997. HIV coreceptor downregulation as antiviral principle: SDF-1α-dependent internalization of the chemokine receptor CXCR4 contributes to inhibition of HIV replication. J. Exp. Med. 186:139-146.
43. Britt, W.J., and C.A. Alford. 1996. Cytomegalovirus. In Virology. 3rd edition. B.N. Field, D.M. Knipe, and P.M. Howley, editors. Lippincott-Raven Publishers, Philadelphia, PA. 2493-2523.
44. Michelson, S. 1998. Mechanisms of immunosuppression by human cytomegalovirus. In CMV-Related Immunopathology, Volume 21. H.F. Rabenau, M. Scholz, H.W. Doerr, and J. Cinalti, Jr., editors. Karger, Basel. 12-28.
45. Michelson, S., J. Alcami, S.J. Kim, D. Danielpour, F. Bachelerie, L. Picard, C. Bessia, C. Paya, and J.L. Virelizier. 1994. Human cytomegalovirus infection induces transcription and secretion of transforming growth factor beta 1. J. Virol. 68: 5730-5737.
46. Kline, J.N., L.J. Geist, M.M. Monick, M.F. Stinski, and G.W. Hunninghake. 1994. Regulation of expression of the IL-1 receptor antagonist (IL-1ra) gene by products of the human cytomegalovirus immediate early genes. J. Immunol. 152: 2351-2357.
47. Macdonald, M.R., X.Y. Li, and H.W. Virgin. 1997. Late expression of a beta chemokine homolog by murine cytomegalovirus. J. Virol. 71:1671-1678.
48. Davis-Poynter, N.J., D.M. Lynch, H. Vally, G.R. Shellam, W.O. Rawlinson, B.C. Barrell, and H.E. Farrell. 1997. Identification and characterization of a G protein-coupled receptor homolog encoded by murine cytomegalovirus. J. Virol. 71:1521-1529.
49. Pleskoff, O., C. Treboute, A. Brelot, N. Heveker, M. Seman, and M. Alizon. 1997. Identification of a chemokine receptor encoded by human cytomegalovirus as a cofactor for HIV-1 entry. Science. 276:1874-1878.
50. Sozzani, S., D. Zhou, M. Locati, M. Rieppi, P. Proost, M. Magazin, N. Vita, J. van Damme, and A. Mantovani. 1994. Receptors and transduction pathways for monocyte chemo-tactic protein-2 and monocyte chemotactic protein-3. Similarities and differences with MCP-1. J. Immunol. 152:3615-3622.
51. Baggiolini, M., B. Dewald, and B. Moser. 1997. Human chemokines: an update. Anna. Rev. Immunol. 15:675-705.
52. Taub, D.D., S.M. Turcovski-Corrales, M.L. Key, D.L. Longo, and W.J. Murphy. 1996. Chemokines and T lymphocyte activation: I. Beta chemokines costimulate human T lymphocyte activation in vitro. J. Immunol. 156:2095-2103.
53. Taub, D.D., J.R. Ortaldo, S.M. Turcovski-Corrales, M.L. Key, D.L. Longo, and W.J. Murphy. 1996. Beta chemokines costimulate lymphocyte cytolysis, proliferation, and lymphokine production. J. Leukocyte Biol. 59:81-89.