The δ-isoform of protein kinase C causes inducible nitric-oxide synthase and nitric oxide up-regulation: Key mechanism for oxidant-induced carbonylation, nitration, and disassembly of the microtubule cytoskeleton and hyperpermeability of barrier of intestinal epithelia

Journal of Pharmacology and Experimental Therapeutics

Volumn 305, Issue 2, 2003, Pages 482-494

  Banan, A ^a,b   Farhadi, A ^a   Fields, J Z ^a   Zhang, L J ^a   Shaikh, M ^a   Keshavarzian, A ^a  

^a RUSH UNIVERSITY MEDICAL CENTER   (United States)

^b RUSH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROGEN PEROXIDE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OXIDIZING AGENT; PROTEIN KINASE C;

ARTICLE; CARBONYLATION; CARCINOMA CELL; CELL FRACTIONATION; CELL PROTECTION; CELL STRAIN CACO 2; CHEMICAL MODIFICATION; CLONE; COLON ADENOCARCINOMA; CONTROLLED STUDY; CYTOARCHITECTURE; CYTOSKELETON; ENZYME ACTIVATION; EXPOSURE; FLUOROMETRY; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; INCUBATION TIME; INTESTINE MUCOSA PERMEABILITY; MICROTUBULE ASSEMBLY; NITRATION; OXIDATION; OXIDATIVE STRESS; PATHOPHYSIOLOGY; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING;

BLOTTING, WESTERN; CACO-2 CELLS; CHEMILUMINESCENT MEASUREMENTS; CYTOSKELETON; FLUORESCENT ANTIBODY TECHNIQUE; FLUOROMETRY; FREE RADICAL SCAVENGERS; HUMANS; INTESTINAL MUCOSA; MICROSCOPY, CONFOCAL; MICROTUBULES; NITRATES; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; OXIDANTS; OXIDATIVE STRESS; PERMEABILITY; PLASMIDS; PRECIPITIN TESTS; PROTEIN KINASE C; PROTEIN KINASE C-DELTA; TRANSFECTION; TUBULIN; UP-REGULATION;

EID: 0037405112     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.102.047308     Document Type: Article

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