Oxidative damage in colon and mammary tissue of the HFE-knockout mouse

Free Radical Biology and Medicine

Volumn 34, Issue 9, 2003, Pages 1212-1216

  Stevens, Richard G ^a   Morris, James E ^b   Cordis, Gerald A ^a   Anderson, Larry E ^b   Rosenberg, Daniel W ^a   Sasser, Lyle B ^b  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^b PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

Author keywords

Free radicals; Hemochromatosis; Iron; MDA; Oxidative stress

Indexed keywords

HFE PROTEIN; IRON; MALONALDEHYDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BREAST DISEASE; COLON INJURY; CONTROLLED STUDY; GENE INTERACTION; GENOTYPE; HEMOCHROMATOSIS; IRON INTAKE; KNOCKOUT GENE; KNOCKOUT MOUSE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; TISSUE LEVEL;

EID: 0037403925     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(03)00072-8     Document Type: Article

References (29)

1. Burke W., Thomson E., Khoury M.J., McDonnell S.M., Press N., Adams P.C., Barton J.C., Beutler E., Brittenham G., Buchanan A., Clayton E.W., Cogswell M.E., Meslin E.M., Motulsky A.G., Powell L.W., Sigal E., Wilfond B.S., Collins F.S. Hereditary hemochromatosis gene discovery and its implications for population-based screening . JAMA. 280:1998;172-178.
2. Bulaj Z.J., Griffen L.M., Jorde L.B., Edwards C.Q., Kushner J.P. Clinical and biochemical abnormalities in people heterozygous for hemochromatosis. N. Engl. J. Med. 335:1996;1799-1805.
3. Cook J.D. Adaptation in iron metabolism. Am. J. Clin. Nutr. 51:1990;301-308.
4. Stevens R.G., Jones D.Y., Micozzi M.S., Taylor P.R. Body iron stores and the risk of cancer. N. Engl. J. Med. 319:1988;1047-1052.
5. Stevens R.G., Beasley R.P., Blumberg B.S. Iron-binding proteins and risk of cancer in Taiwan. J. Natl. Cancer Inst. 76:1986;605-610.
6. Thompson H.J., Kennedy K., Witt M., Juzefyk J. Effect of dietary iron deficiency or excess on the induction of mammary carcinogenesis by 1-methyl-1-nitrosourea. Carcinogenesis. 12:1991;111-114.
7. Diwan B.A., Kasprzak K.S., Anderson L.M. Promotion of dimethylbenz(a)anthracene-initiated mammary carcinogenesis by iron in female Sprague-Dawley rats. Carcinogenesis. 18:1997;1757-1762.
8. Siegers C.P., Bumann D., Baretton G., Younes M. Dietary iron enhances the tumor rate in dimethylhydrazine-induced colon carcinogenesis in mice. Cancer Lett. 41:1988;251-256.
9. Stevens R.G., Morris J.E., Anderson L.E. Hemochromatosis heterozygotes may constitute a radiation-sensitive subpopulation. Radiat. Res. 153:2000;844-847.
10. Zhou X.Y., Tomatsu S., Fleming R.E., Parkkila S., Waheed A., Jiang J., Fei Y., Brunt E.M., Ruddy D.A., Prass C.E., Schatzman R.C., O'Neill R., Britton R.S., Bacon B.R., Sly W.S. HFE gene knockout produces mouse model of hereditary hemochromatosis. Proc. Natl. Acad. Sci. USA. 95:1998;2492-2497.
11. Waheed A., Parkkila S., Zhou X.Y., Tomatsu S., Tsuchihashi Z., Feder J.N., Schatzman R.C., Britton R.S., Bacon B.R., Sly W.S. Hereditary hemochromatosis effects of C282Y and H63D mutations on association with β2-microglobulin, intracellular processing, and cell surface expression of the HFE protein in COS-7 cells . Proc. Natl. Acad. Sci. USA. 94:1997;12384-12389.
12. Waheed A., Parkkila S., Saarnio J., Fleming R.E., Zhou X.Y., Tomatsu S., Britton R.S., Bacon B.R., Sly W.S. Association of HFE protein with transferrin receptor in crypt enterocytes of human duodenum. Proc. Natl. Acad. Sci. USA. 96:1999;1579-1584.
13. Fleming R.E., Holden C.C., Tomatsu S., Waheed A., Brunt E.M., Britton R.S., Bacon B.R., Roopenian D.C., Sly W.S. Mouse strain differences determine severity of iron accumulation in HFE knockout model of hereditary hemochromatosis. Proc. Natl. Acad. Sci. USA. 98:2001;2707-2711.
14. Torrance, J. D.; Bothwell, T. H. Tissue iron stores. In: Cook, J. D., ed. Methods hematology. 1980:90-115.
15. Stahr S.M. Analytical methods in hematology. 1991;71-73 John Wiley & Sons, Inc, New York.
16. Cordis G.A., Maulik N., Das D.K. Detection of oxidative stress in heart by estimating the dinitrophenylhydrazine derivative of malonaldehyde. J. Mol. Cell. Cardiol. 27:1995;1645-1653.
17. Cordis G.A., Maulik G., Bagchi D., Riedel W., Das D.K. Detection of oxidative DNA damage to ischemic reperfused rat hearts by 8-hydroxydeoxyguanosine formation. J. Mol. Cell. Cardiol. 30:1998;1939-1944.
18. Cordis G.A., Das D.K., Riedel W. High-performance liquid chromatographic peak identification of 2,4-dinitrophenylhydrazine derivatives of lipid peroxidation aldehydes by photodiode array detection. J. Chromatogr. A. 798:1998;117-123.
19. Sawa T., Akaike T., Kida K., Fukushima Y., Takagi K., Maeda H. Lipid peroxyl radicals from oxidized oils and heme iron implication of a high-fat diet in colon carcinogenesis . Cancer Epidemiol. Biomarkers Prev. 7:1998;1007-1012.
20. Shaheen N.J., Silverman L.M., Keku T., Mawrence L.B., Rohlfs E.M., Martin C.F., Galanko J., Sandler R.S. Association between hemochromatosis (HFE) gene mutation carrier status and risk of colon cancer. J. Natl. Cancer Inst. 95:2003;154-159.
21. Ajioka R.S., Levy J.E., Andrews N.C., Kushner J.P. Regulation of iron absorption in HFE mutant mice. Blood. 100:2002;1465-1469.
22. Halliwell B., Gutteridge J.M.C. Role of free radicals and catalytic metal ions in human disease an overview . Methods Enzymol. 186:1990;1-85.
23. Toyokuni S. Iron-induced carcinogenesis the role of redox cycling . Free Radic. Biol. Med. 20:1996;553-566.
24. Brown K.E., Knudsen C.A. Oxidized heme proteins in an animal model of hemochromatosis. Free Radic. Biol. Med. 24:1998;239-244.
25. Chitambar C.R., Wereley J.P. Iron transport in a lymphoid cell line with the hemochromatosis C282Y mutation. Blood. 97:2001;2734-2740.
26. Sesink A.L., Termont D.S., Kleibeuker J.H., Van der Meer R. Red meat and colon cancer the cytotoxic and hyperproliferative effects of dietary heme . Cancer Res. 59:1999;5704-5709.
27. Malins D.C., Polissar N.L., Gunselman S.J. Progression of human breast cancers to the metastatic state is linked to hydroxyl radical-induced DNA damage. Proc. Natl. Acad. Sci. USA. 93:1996;2557-2563.
28. Malins D.C., Polissar N.L., Su Y., Gardner H.S., Gunselman S.J. A new structural analysis of DNA using statistical models of infrared spectra. Nat. Med. 3:1997;927-930.
29. Nelson J.M., Stevens R.G. Ferritin-iron increases killing of chinese hamster ovary cells by x irradiation. Cell Prolif. 25:1992;579-585.