Zinc toxicity on neonatal cortical neurons: Involvement of glutathione chelation

Journal of Neurochemistry

Volumn 85, Issue 2, 2003, Pages 443-453

  Chen, Chun Jung ^a   Liao, Su Lan ^a  

^a TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

Chelation; Glutathione; Neuron; Neurotoxicity; Pyruvate; Zinc

Indexed keywords

ACETYLCYSTEINE; CALCIUM; GLUTATHIONE; LACTIC ACID; MALEIC ACID DERIVATIVE; PYRROLIDINE DITHIOCARBAMATE; PYRUVIC ACID; THIOL DERIVATIVE; ZINC;

ANIMAL CELL; ARTICLE; BRAIN CELL; CELL SURVIVAL; CHELATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; GLIA; HOMEOSTASIS; NERVE CELL EXCITABILITY; NERVE CELL LESION; NERVE CELL NECROSIS; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0037389030     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2003.01691.x     Document Type: Article

References (57)

1. Ahn Y. H., Kim Y. H., Hong S. H. and Koh J. H. (1998) Depletion of intracellular zinc induces protein synthesis-dependent neuronal apoptosis in mouse cortical culture. Exp. Neurol. 154, 47-56.
2. Ardite E., Sans M., Panes J., Romero F. J., Pique J. M. and FernandezCheca J. C. (2000) Replenishment of glutathione levels improves mucosal function in experimental acute colitis. Lab. Invest. 80, 735-744.
3. Aruoma O. J., Halliwell B., Hoey B. M. and Burtler J. (1989) The antioxidant action of N-acetylcysteine: its reaction with hydrogen peroxide, hydroxyl radical, superoxide and hypochlorous acid. Free Radic. Biol. Med. 6, 593-597.
4. 2+ from brain tissue during activity. Nature 308, 734-736.
5. Bains J. S. and Shaw C. A. (1997) Neurodegenerative disorders in humans: the role of glutathione in oxidative stress-mediated neuronal death. Brain Res. Rev. 25, 335-358.
6. Beaver J. P. and Waring P. (1995) A decrease in intracellular glutathione concentration precedes the onset of apoptosis in murine thymocytes. Eur. J. Cell Biol. 68, 47-54.
7. Bray T. M. and Bettger W. J. (1990) The physiological role of zinc as an antioxidant. Free Radic. Biol. Med. 8, 281-291.
8. Canals S., Casarejos M. J., de Bernardo S., Rodríguez-Martín E. and Mena M. A. (2001) Glutathione depletion switches nitric oxide neurotrophic effects to cell death in midbrain cultures: implications for Parkinson's disease. J. Neurochem. 79, 1183-1195.
9. Chen C. J., Liao S. L. and Kuo J. S. (2000a) Gliotoxic action of glutamate on cultured astrocytes. J. Neurochem. 75, 1557-1565.
10. Chen C. J., Liao S. L., Kuo M. D. and Wang Y. M. (2000b) Astrocytic alteration induced by Japanese encephalitis virus infection. Neuroreport 11, 1933-1937.
11. Choi D. W. and Koh J. K. (1998) Zinc and brain injury. Annu. Rev. Neurosci. 21, 347-375.
12. Choi D. W., Yokoyama M. and Koh J. (1988) Zinc neurotoxicity in cortical cell culture. Neuroscience 24, 67-79.
13. Christine C. W. and Choi D. W. (1990) Effect of zinc on NMDA receptor-mediated channel currents in cortical neurons. J. Neurosci. 10, 108-116.
14. Coudray C., Boucher F., Richard M. J., Arnaud J., De Leiris J. and Favier A. (1991) Zinc deficiency, ethanol, and myocardial ischemia affect lipoperoxidation in rats. Biol. Trace Elem. Res. 30, 103-118.
15. Devesa A., O'Connor J. E., García C., Puertes I. R. and Vina J. R. (1993) Glutathione metabolism in primary astrocyte cultures: flow cytometric evidence of heterogeneous distribution of GSH content. Brain Res. 618, 181-189.
16. Dringen R. (2000) Metabolism and functions of glutathione in brain. Prog. Neurobiol. 62, 649-671.
17. Dringen R., Gutterer J. M., Gros C. and Hirrlinger J. (2001) Aminopeptidase N mediates the utilization of the GSH precursor CysGly by cultured neurons. J. Neurosci. Res. 66, 1003-1008.
18. Frederickson C. J., Klitenick M. A., Manton W. I. and Kirkpatrick J. B. (1983) Cytoarchitectonic distribution of zinc in the hippocampus of man and the rat. Brain Res. 273, 335-339.
19. Frederickson C. J., Klitenick M. A., Manton W. I. and Kirkpatrick J. B. (1987) A quinoline fluorescence method for visualization and assaying the histochemically reactive zinc (bouton zinc) in the brain. J Neurosci. Meth. 20, 91-103.
20. Gunaratnam M. and Grant M. H. (2001) The role of glutathione reductase in the cytotoxicity of chromium (VI) in isolated rat hepatocytes. Chem. Biol. Interact. 134, 191-202.
21. Hill W. D., Hess D. C., Carroll J. E., Wakade C. G., Howard E. F., Chen Q., Cheng C., Martin-Studdard A., Waller J. L. and Beswick R. A. (2001) The NF-κB inhibitor diethyldithiocarbamate (DDTC) increases brain cell death in a transient middle cerebral artery occlusion model of ischemia. Brain Res. Bull. 55, 375-386.
22. Kim Y. H., Kim E. Y., Gwag B. J., Sohn S. and Koh J. Y. (1999) Zinc-induced cortical neuronal death with features of apoptosis and necrosis: mediation by free radicals. Neuroscience 89, 175-182.
23. Kirino T. (1982) Delayed neuronal death in the gerbil hippocampus following ischemia. Brain Res. 239, 57-69.
24. Koh J. Y. and Choi D. W. (1987) Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay. J. Neurosci. Meth. 20, 83-90.
25. Koh J. Y. and Choi D. W. (1994) Zinc toxicity on cultured cortical neurons: involvement of N-methyl-D-aspartate receptors. Neuroscience 60, 1049-1057.
26. Koh J. Y., Suh S. W., Gwag B. J., He Y. Y., Hsu C. Y. and Choi D. W. (1996) The role of zinc in selective neuronal death after transient global cerebral ischemia. Science 272, 1013-1016.
27. Leccia M. T., Richard M. J., Favier A. and Beani J. C. (1999) Zinc protects against ultraviolet Al-induced DNA damage and apoptosis in cultured human fibroblasts. Biol. Trace Elem. Res. 69, 177-190.
28. Lees G. J., Lehmann A., Sandberg M. and Hamberger A. (1990) The neurotoxicity of zinc in the rat hippocampus. Neurosci. Lett. 120, 155-158.
29. Li Y., Maher P. and Schubert D. (1997) A role for 12-lipoxygenase in nerve cell death caused by glutathione depletion. Neuron 19, 453-463.
30. Manev H., Kharlamov E., Uz T., Mason R. P. and Cagnoli C. M. (1997) Characterization of zinc-induced neuronal death in primary cultures of rat cerebellar granule cells. Exp. Neurol. 146, 171-178.
31. Marin P., Israël M., Glowinski J. and Prémont J. (2000) Routes of zinc entry in mouse cortical neurons: role in zinc-induced neurotoxicity. Eur. J. Neurosci. 12, 8-18.
32. Marklund S. L., Westman N. G., Lundgren E. and Roos G. (1982) Copper- and zinc-containing superoxide dismutase, manganese-containing superoxide dismutase, catalase, and glutathione peroxidase in normal and neoplastic human cell lines and normal human tissues. Cancer Res. 42, 1955-1961.
33. McKenna M. C., Tildon J. T., Stevenson J. H. J., Boatreght R. and Huang S. (1993) Regulation of energy metabolism in synaptic terminals and cultured rat brain astrocytes: difference revealed using amniooxyacetate. Dev. Neurosci. 15, 320-329.
34. Meister A. and Anderson M. E. (1983) Glutathione. Annu. Rev. Biochem. 52, 711-760.
35. Noh K. M. and Koh J. Y. (2000) Induction and activation by zinc of NADPH oxidase in cultured cortical neurons and astrocytes. J. Neurosci. 20, 1-5.
36. Oja S. S., Janaky R., Varga V. and Saransaari P. (2000) Modulation of glutamate receptor functions by glutathione. Neurochem. Int. 37, 299-306.
37. Papadopoulos M. C., Koumenis I. L., Xu L. and Giffard R. G. (1998) Potentiation of murine astrocyte antioxidant defence by bcl-2: protection in part reflects elevated glutathione levels. Eur. J. Neurosci. 10, 1252-1260.
38. Parat M. O., Richard M. J., Beani J. C. and Favier A. (1997) Involvement of zinc in intracellular oxidant/antioxidant balance. Biol. Trace Elem. Res. 60, 187-204.
39. NTR-associated death executor in neurons after zinc exposure in cortical cultures or transient ischemia in the rat. J. Neurosci. 20, 9096-9103.
40. Peters S., Koh J. Y. and Choi D. W. (1987) Zinc selective blocks the action of N-Methyl-D-aspartate on cortical neurons. Science 236, 589-593.
41. Pulsinelli W. A. (1985) Selective neuronal vulnerability: morphological and molecular characteristics. Prog. Brain Res. 63, 29-37.
42. Rehncrona S., Folbergrova J., Smith D. S. and Siesjo B. K. (1980) Influence of complete and pronounced incomplete cerebral ischemia and subsequent recirculation on cortical concentrations of oxidized and reduced glutathione in the rat. J. Neurochem. 34, 477-486.
43. Richardson R. J. and Murphy S. D. (1975) Effect of glutathione depletion on tissue deposition of methylmercury in rats. Toxicol. Appl. Pharmacol. 31, 505-519.
44. Schapira A. H., Cooper J. M., Dexter D., Clark J. B., Jenner P. and Marsden C. D. (1990) Mitochondrial complex I deficiency in Parkinson's disease. J. Neurochem. 54, 823-827.
45. Schulz J. B., Lindenau J., Seyfried J. and Dichgans J. (2000) Glutathione, oxidative stress and neurodegeneration. Eur. J. Biochem. 267, 4904-4911.
46. Schurr A., Miller J. J., Payne R. S. and Rigor B. M. (1999) An increase in lactate output by brain tissue serves to meet the energy needs of glutamate-activated neurons. J. Neurosci. 19, 34-39.
47. + and inhibition of glycolysis. J Neurosci. 20, 3139-3145.
48. Sian J., Dexter D. T., Lees A. J., Daniel S. E., Agid Y., Javoy-Agid F., Jenner P. and Marsden C. D. (1994) Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia. Ann. Neurol. 36, 348-355.
49. Tate D. J., Miceli M. V. and Newsome D. A. (1997) Zinc induces catalase expression in cultured fetal human retinal pigment epithelial cells. Curr. Eye Res. 16, 1017-1023.
50. Thornally P. J. and Vasak, M. (1985) Possible for metallothionein protection against human retinal pigment epithelium. Biochem. Biophys. Acta 827, 36-44.
51. Trombetta L. D., Toulon M. and Jamall I. S. (1988) Protective effects of glutathione on diethyldithiocarbamate (DDC) cytotoxicity: a possible mechanism. Toxicol. Appl. Pharmacol. 93, 154-164.
52. Tsai J. C., Jain M., Hsieh C. M., Lee W. S., Yoshizumi M., Patterson C., Perrella M. A., Cooke C., Wang H., Haber E., Schlegel R. and Lee E. M. (1996) Induction of apoptosis by pyrrolidine dithiocarbamate and N-acetylcysteine in vascular smooth muscle cells. J. Biol. Chem. 271, 3667-3670.
53. Weber G. F. (1999) Final pathways in neurodegenerative diseases: regulatory role of the glutathione cycle. Neurosci. Biobehav. Rev. 23, 1079-1086.
54. Weiss J. H., Hartley D. M., Koh J. Y. and Choi D. W. (1993) AMPA receptor activation potentiates zinc neurotoxicity. Neuron 10, 43-49.
55. Wu M., Lee H., Bellas R. E., Schauer S. L., Arsura M., Katz D., FitzGerald M. J., Rothstein T. L., Sherr D. H. and Sonenshein G. E, (1996) Inhibition of NF-κB/Rel induces apoptosis of murine B cells. EMBO J. 15, 4682-4690.
56. Yokoyama M., Koh J. and Choi D. W. (1986) Brief exposure to zinc is toxic to cortical neurons. Neurosci. Lett. 71, 351-355.
57. Zhao Y. Y., Yang G. Y. and Domino E. F. (1996) Zinc protoporphyrin, zinc ion, and protoporphyrin reduce focal cerebral ischemia. Stroke 27, 2299-2303.