Neurobehavioral effects during experimental exposure to 1-octanol and isopropanol

Scandinavian Journal of Work, Environment and Health

Volumn 29, Issue 2, 2003, Pages 143-151

  van Thriel, Christoph ^a   Kiesswetter, Ernst ^a   Blaszkewicz, Meinolf ^a   Golka, Klaus ^a   Seeber, Andreas ^a  

^a LEIBNIZ RESEARCH CENTRE FOR WORKING ENVIRONMENT AND HUMAN FACTORS   (Germany)

Author keywords

Alcohols; Chemical sensitivity; Distraction; Neuropsychology of attention

Indexed keywords

2 PROPANOL; OCTANOL;

NEUROLOGY;

ADULT; ANNOYANCE; ARTICLE; ATTENTION; CHEMOSENSITIVITY; COGNITIVE DEFECT; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CROSSOVER PROCEDURE; DOSE RESPONSE; FATIGUE; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; OCCUPATIONAL EXPOSURE; PRIORITY JOURNAL; PSYCHOLOGIC TEST; SENSORY DYSFUNCTION; SMELLING DISORDER; SYMPTOMATOLOGY; TASK PERFORMANCE; VOLUNTEER;

EID: 0037388210     PISSN: 03553140     EISSN: None     Source Type: Journal    
DOI: 10.5271/sjweh.716     Document Type: Article

References (31)

1. Litovitz T. The alcohols: ethanol, methanol, isopropanol, ethylene glycol. Pediatr Clin North Am 1986;33(2):311-23.
2. Sethre T, Läubli T, Berode M, Krueger H. Neurobehavioural effects of experimental isopropanol exposure. Int Arch Occup Environ Health 2000;73:105-12.
3. Muttray A, Jung D, Rose DM, Hommel G, Konietzko J. Acute effects of exposure to 360 ppm Isopropanol on healthy man. Centr Eur J Occup Environ Med 1998;4:288-93.
4. Triebig G, Fritz M, Schaller KH, Helbing F, Bünte EM, Kufner K, et al. Arbeitsmedizinische Untersuchungen bei beruflich Iso-Propanol-exponierten Frauen. [Medical investigation of women occupationally exposed to isopropanol.] Arbeitsmed Sozialmed Präventivmed 1989;24:27-31.
5. Sethre T, Läubli T, Riediker M, Hangartner M, Krueger H. Neurobehavioral effects of low level solvent exposures in a foundry. Centr Eur J Occup Environ Med 1998;4:316-27.
6. Maizlish NA, Langolf GD, Whitehead LW, Fine LJ, Albers JW, Goldberg J, et al. Behavioural evaluation of workers exposed to mixtures of organic solvents. Br J Ind Med 1985; 42:579-90.
7. Deutsche Forschungsgemeinschaft (DFG). List of MAK and BAT values 2000: maximum concentrations and biological tolerance values at the workplace. Weinheim (Germany): Wiley-VCH; 2000
8. American Conference of Governmental Industrial Hygienists (ACGIH). 2000 TLVs and BEIs: threshold limit values for chemical substances and physical agents biological exposure indices. Cincinnati (OH): ACGIH Worldwide; 2000.
9. Dalton PH, Dilks DD, Banton MI. Evaluation of odor and sensory irritation thresholds of methyl isobutyl ketone in humans. Am Ind Hyg Assoc J 2000;61:340-50
10. Deutsche Forschungsgemeinschaft (DFG). Gesundheitsschädliche Arbeitsstoffe. Toxikologisch-arbeitsmedizinische Begründung von MAK-Werten: 2-ethylhexanol. MAK, 30. Lieferung. Weinheim (Germany): Wiley-VCH; 2000.
11. American Industrial Hygienic Association (AIHA). Work-place environmental exposure level [WEEL] 1-octanol. Fairfax (VA): AIHA Press; 1992.
12. Cometto-Muniz JE, Cain WS. Thresholds for odor and nasal pungency. Physiol Behav 1990;48:719-25.
13. Cometto-Muniz JE, Cain WS. Trigeminal and olfactory sensitivity: comparison of modalities and methods of measurement. Int Arch Occup Environ Health 1998;71:105-10.
14. Cometto-Muniz JE, Cain WS. Efficacy of volatile organic compounds in evoking nasal pungency and odor. Arch Environ Health 1993;48:309-14.
15. Fang Z, Ionescu P, Chortkoff BS, Kandel L, Sonner J, Laster MJ, et al. Anesthetic potencies of n-alkanols: results of additivity and solubility studies suggest a mechanism of action similar to that for conventional inhaled anesthetics. Anesth Analg 1997;84:1042-8.
16. Bell IR, Miller CS, Schwartz GE, Peterson JM, Amend D. Neuropsychiatric and somatic characteristics of young adults with and without self-reported chemical odor intolerance and chemical sensitivity. Arch Environ Health 1996;51:9-21.
17. Kiesswetter E, Sietmann B, Zupanic M, van Thriel C, Golka K, Seeber A. Verhaltenstoxische Aspekte der Prävalenz und Ätiologie "multipler chemischer Sensitivität" [Neurobehavioral aspects of the prevalence and etiology of "multiple chemical sensitivity"]. Allergologie 1999;22:719-35.
18. Ruth JH. Odor threshold and irritation levels of several chemical substances: a review. Am Ind Hyg Assoc J 1986;47:142-51.
19. Seeber A, Blaszkewicz M, Golka K, Kiesswetter E. Solvent exposure and ratings of well-being: dose-effect relationships and consistency of data. Environ Res 1997;73:81-91.
20. Gamberale F, Iregren A, Kjellberg A. Computerized performance testing in neurotoxicology. Why, what, how and whereto? The SPES example. In: Russel RW, Flattau PE, Pope AM, editors. Behavioral measures of neurotoxicity. Washington (DC): National Academy Press; 1990. p 359.
21. Iregren A. Computer-assisted testing. In: Costa LG, Manzo L, editors. Occupational neurotoxicology. Boca Raton (FL): CRC Press; 1998. p 213-31.
22. Zimmermann P, Fimm B. Testbatterie zur Aufmerksamkeitsprüfung (TAP) Version 1.0. Würselen: PSYTEST; 1993.
23. Parasuraman R, Warm JS, See JE. Brain systems of vigilance. In: Parasuraman R, editor. The attentive Brain. Cambridge (MA): MIT Press; 2000. p 221-56.
24. SPSS Inc. SPSS 10.0 Syntax Reference Guide. Chicago (IL): SPSS Inc; 1999.
25. Bortz J, Lienert GA, Boehnke K. Verteilungsfreie Methoden in der Biostatistik. Berlin: Springer-Verlag; 1990.
26. Smeets MA, Mauté C, Dalton PH. Acute sensory irritations from exposure to isopropanol (2-propanol) at TLV in workers and controls: objective versus subjective effects. Ann Occup Hyg 2002;46:359-73.
27. Dick RB. Short duration exposures to organic solvents: The relationship between neurobehavioral test results and other indicators. Neurotoxicol Teratol 1988;10:39-50.
28. Muttray A, Kurten R, Jung D, Schicketanz KH, Mayer-Popken O, Konietzko J. Acute effects of 200 ppm 1,1,1-trichloroethane on the human EEG. Eur J Med Res 2000;5:375-84.
29. Dick RB, Ahlers H. Chemicals in the workplace: incorporating human neurobehavioral testing into the regulatory process. Am J Ind Med 1998;33:439-53.
30. Norman DA, Shallice T. Attention to action: willed and automatic control of behavior. In: Davidson RJ, Schwartz GE, Shapiro D, editors. Consciousness and self-regulation. New York (NY): Plenum Press; 986. p 1-18.
31. Dalton P, Wysocki CJ, Brody MJ, Lawley HJ. The influence of cognitive bias on the perceived odor, irritation and health symptoms from chemical exposure. Int Arch Occup Environ Health 1997;69:407-17.