COPD: Is chemotaxis the key?

Chest

Volumn 123, Issue 4, 2003, Pages 983-986

  Balbi, Bruno ^a  

^a IRCCS   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; ANTIOXIDANT; CHEMOATTRACTANT; CHEMOTACTIC FACTOR; INTERLEUKIN 8; LEUKOTRIENE B4; PROTEINASE INHIBITOR;

CHEMOTAXIS; CHRONIC BRONCHITIS; CHRONIC OBSTRUCTIVE LUNG DISEASE; EDITORIAL; HUMAN; INFLAMMATION; MACROPHAGE; MONONUCLEAR CELL; NEUTROPHIL; POLYMORPHONUCLEAR CELL; PRIORITY JOURNAL; QUANTITATIVE ASSAY; SMOKING;

EID: 0037387578     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.123.4.983     Document Type: Editorial

References (33)

1. Chodosh S. Examination of sputum cells. N Engl J Med 1970; 282:854-857
2. Saetta M, Di Stefano A, Maestrelli P, et al. Activated T-lymphocytes, and macrophages, in bronchial mucosa of subjects with chronic bronchitis. Am Rev Respir Dis 1993; 147:301-306
3. Di Stefano A, Turato G, Maestrelli P, et al. Up-regulation of adhesion molecules in the bronchial mucosa of subjects with chronic obstructive bronchitis. Am J Respir Crit Care Med 1994; 149:803-810
4. Jeffery PK. Structural and inflammatory changes in COPD: a comparison with asthma. Thorax 1998; 53:129-136
5. Di Stefano A, Capelli A, Lusuardi M, et al. Decreased T lymphocyte infiltration in bronchial biopsies of subjects with severe chronic obstructive pulmonary disease. Clin Exp Allergy 2001; 31:893-902
6. Saetta M, Mariani M, Panina-Bordignon P, et al. Increased expression of the chemokine receptor CXCR3 and its ligand CXCL10 in peripheral airways of smokers with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2002; 165:1404-1409
7. Blue ML, Janoff A. Possible mechanisms of emphysema in cigarette smokers: release of elastase from human polymorphonuclear leukocytes by cigarette smoke condensate in vitro. Am Rev Respir Dis 1978; 117:317-325
8. Sato E, Koyama S, Takamizawa A, et al. Smoke extract stimulates lung fibroblasts to release neutrophil and monocyte chemotactic activities. Am J Physiol 1999; 277:L1149-L1157
9. Holland SM, Gallin JL. Neutrophils. In: Crystal RG, West JB, Weibel ER, et al, eds. The lung scientific foundations. 2nd ed. Philadelphia, PA: Lippincott-Raven, 1997; 877-890
10. Pan ZZ, Parkyn L, Ray A, et al. Inducible lung-specific expression of RANTES: preferential recruitment of neutrophils. Am J Physiol 2000; 279:L658-L666
11. Parmar JS, Mahadeva R, Reed BJ, et al. Polymers of alpha(1)-antitrypsin are chemotactic for human neutrophils: a new paradigm for the pathogenesis of emphysema. Am J Respir Cell Mol Biol 2002; 26:723-730
12. Gompertz S, Stockley RA. A randomized, placebo-controlled trial of a leukotriene synthesis inhibitor in patients with COPD. Chest 2002; 122:289-294
13. Barnes PJ. Chronic obstructive pulmonary disease. N Engl J Med 2000; 343:269-280
14. Pauwels RA, Buist S, Calverley PMA, et al. Global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease: NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) workshop summary. Am J Respir Crit Care Med 2001; 163:1256-1276
15. Riise GC, Ahlstedt S, Larsson S, et al. Bronchial inflammation in chronic bronchitis assessed by measurements of cell products in bronchial lavage fluid. Thorax 1995; 50:360-365
16. Pesci A, Balbi B, Majori M, et al. Inflammatory cells and mediators in bronchial lavage of patients with chronic obstructive pulmonary disease. Eur Respir J 1998; 12:380-386
17. Balbi B, Majori M, Bertacco S, et al. Inhaled corticosteroids in stable COPD patients: do they have effects on cells and molecular mediators of airway inflammation? Chest 2000; 117:1633-1637
18. Tanino M, Betsuyaku T, Takeyabu K, et al. Increased levels of interleukin-8 in BAL fluid from smokers susceptible to pulmonary emphysema. Thorax 2002; 57:405-411
19. Keatings VM, Collins PD, Scott DM, et al. Differences in interleukin-8 and tumor necrosis factor-alpha in induced sputum from patients with chronic obstructive pulmonary disease or asthma. Am J Respir Crit Care Med 1996; 153:530-534
20. Mikami M, Llewellyn-Jones CG, Bayley D, et al. The chemotactic activity of sputum from patients with bronchiectasis. Am J Respir Crit Care Med 1998; 157:723-728
21. Traves SL, Culpitt SV, Russell REK, et al. Increased levels of the chemokines GROα and MCP-1 in sputum samples from patients with COPD. Thorax 2002; 57:590-595
22. Seggev JS, Thornton WH Jr, Edes TE. Serum leukotriene B4 levels in patients with obstructive pulmonary disease. Chest 1991; 99:289-291
23. De Boer WI, Sont JK, van Schadewijk A, et al. Monocyte chemoattractant protein 1, interleukin-8, and chronic airways inflammation in COPD. J Pathol 2000; 190:619-626
24. Boyden SE Jr. The chemotactic effects of mixtures of antibody and antigen on polymorphonuclear leukocytes. J Exp Med 1962; 115:453-466
25. Marshall LJ, Perks B, Ferkol T, et al. IL-8 released constitutively by primary bronchial epithelial cells in culture forms an inactive complex with secretory component. J Immunol 2001; 167:2816-2823
26. Pignatti P, Delmastro M, Perfetti L, et al. Is dithiothreitol affecting cells and soluble mediators during sputum processing? A modified methodology to process sputum. J Allergy Clin Immunol 2002; 110:667-668
27. Kelly MM, Leigh R, Horsewood P, et al. Induced sputum: validity of fluid-phase IL-5 measurement. J Allergy Clin Immunol 2000; 105:1162-1168
28. Rutgers SR, Postma DS, ten Hacken NH, et al. Ongoing airway inflammation in patients with COPD who do not currently smoke. Thorax 2000; 55:12-18
29. Lusuardi M, Capelli A, Cerutti CG, et al. Airways inflammation in subjects with chronic bronchitis who have never smoked. Thorax 1994; 489:1211-1216
30. Di Stefano A, Capelli A, Lusuardi M, et al. Severity of airflow limitation is associated with severity of airway inflammation in smokers. Am J Respir Crit Care Med 1998; 158:1277-1285
31. Hautamaki RD, Kobayashi DK, Senior RM, et al. Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice. Science 1997; 277:2002-2004
32. Mantovani A. The chemokine system: redundancy for robust outputs. Immunol Today 1999; 20:254-257
33. Culpitt SV, de Matos C, Russell RE, et al. Effect of theophylline on induced sputum inflammatory indices and neutrophil chemotaxis in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2002; 165:1371-1376