Inducible lung-specific expression of RANTES: Preferential recruitment of neutrophils

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 279, Issue 4 23-4, 2000, Pages

  Pan, Zhong Zong ^a   Parkyn, Lisa ^a   Ray, Anuradha ^a   Ray, Prabir ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Chemokine; Lung inflammation; Regulated on activation normal T cells expressed and secreted; Transgenic mice

Indexed keywords

GAMMA INTERFERON; MACROPHAGE INFLAMMATORY PROTEIN 2; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 2; RANTES;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ASTHMA; CONTROLLED STUDY; IMMUNOREGULATION; LEUKOCYTE ACTIVATION; LUNG; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE ACTIVATION; TISSUE SPECIFICITY;

EID: 0033681571     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.2000.279.4.l658     Document Type: Article

References (56)

1. Aggregation of RANTES is responsible for its inflammatory properties. Characterization of nonaggregating, noninflammatory RANTES mutants
2. Macrophage inflammatory proteins MIP-1 and MIP-2 are involved in T-cell-mediated neutrophil recruitment
3. Polyclonal antibody directed against human RANTES ameliorates disease in the Lewis rat adjuvant-induced arthritis model
4. RSV infection of human airway epithelial cells causes production of the β-chemokine RANTES
5. Expression of RANTES mRNA and protein in airways of patients with mild asthma
6. Up-regulation of CCR1 and CCR3 and induction of chemotaxis to CC chemokines by IFN-γ in human neutrophils
7. In vitro incubation with influenza virus primes human polymorphonuclear leukocyte generation of superoxide
8. A common cold virus, rhinovirus 16, potentiates airway inflammation after segmental antigen bronchoprovocation in allergic subjects
9. Dissection of thymocyte signaling pathways by in vivo expression of pertussis toxin ADP-ribosyltransferase
10. Induction of airway mucus production by T helper 2 (Th2) cells: A critical role for interleukin 4 in cell recruitment but not mucus production
11. Cloning and functional expression of CC CKR5, a human monocyte CC chemokine receptor selective for MIP-1(α), MIP-1(β), and RANTES
12. Cloning, expression, and characterization of the human eosinophil eotaxin receptor
13. Production of the RANTES chemokine in delayed-type hypersensitivity reactions: Involvement of macrophages and endothelial cells
14. Neutralization of macrophage inflammatory protein 2 (MIP-2) and MIP-1α attenuates neutrophil recruitment in the central nervous system during experimental bacterial meningitis
15. The C-C chemokine receptor antagonist met-RANTES inhibits eosinophil effector functions
16. Modulation of neutrophil influx in glomerulonephritis in the rat with antimacrophage inflammatory protein-2 (MIP-2) antibody
17. Structure and functional expression of the human macrophage inflammatory protein 1α/RANTES receptor
18. The coordinated action of CC chemokines in the lung orchestrates allergic inflammation and airway hyperresponsiveness
19. Transcriptional activation by tetracyclines in mammalian cells
20. Depletion of eosinophils in mice through the use of antibodies specific for C-C chemokine receptor 3 (CCR3)
21. Monocyte chemoattractant protein- 1 is sufficient for the chemotaxis of monocytes and lymphocytes in transgenic mice but requires an additional stimulus for inflammatory activation
22. Release of RANTES, MIP-1α, and MCP- 1 into asthmatic airways following endobronchial allergen challenge
23. Analysis of T cell subsets and β-chemokines in patients with pulmonary sarcoidosis
24. Human airway smooth muscle cells express and release RANTES in response to T helper 1 cytokines: Regulation by T helper 2 cytokines and corticosteroids
25. Chronic inflammation upregulates chemokine receptors and induces neutrophil migration to monocyte chemoattractant protein- 1
26. Cytokine RANTES released by thrombin-stimulated platelets is a potent attractant for human eosinophils
27. Glucocorticoid inhibition of RANTES expression in human lung epithelial cells
28. The role of interleukin-5, interleukin- 8 and RANTES in the chemotactic attraction of eosinophils to the allergic lung
29. Th2-induced eotaxin expression and eosinophilia coexist with Th 1 responses at the effector stage of lung inflammation
30. C-C chemokine-induced eosinophil chemotaxis during allergic airway inflammation
31. Differential recruitment of leukocyte populations and alteration of airway hyperreactivity by C-C family chemokines in allergic airway inflammation
32. Regulation of the production of the RANTES chemokine by endothelial cells. Synergistic induction by IFN-γ plus TNF-α and inhibition by IL-4 and IL- 13
33. Formation of eosinophilic and monocytic intradermal inflammatory sites in the dog by injection of human RANTES but not human monocyte chemoattractant protein 1, human macrophage inflammatory protein 1α, or human interleukin 8
34. Genomic organization and transcriptional regulation of the RANTES chemokine gene
35. Molecular cloning, functional expression, and signaling characteristics of a C-C chemokine receptor
36. Molecular characterization of two murine eosinophil β-chemokine receptors
37. Molecular cloning and functional characterization of a novel human CC chemokine receptor (CCR5) for RANTES, MIP-1β, and MIP-1β
38. Expression of the cytokine RANTES in human rheumatoid synovial fibroblasts. Differential regulation of RANTES and interleukin- 8 genes by inflammatory cytokines
39. Regulated overexpression of interleukin 11 in the lung. Use to dissociate development-dependent and -independent phenotypes
40. RANTES and macrophage inflammatory protein 1 α induce the migration and activation of normal human eosinophil granulocytes
41. Respiratory syncytial virus induces selective production of the chemokine RANTES by upper airway epithelial cells
42. Molecular cloning and functional expression of a new human CC-chemokine receptor gene
43. Selective attraction of monocytes and T lymphocytes of the memory phenotype by cytokine RANTES
44. Molecular cloning and expression of the murine RANTES cytokine: Structural and functional conservation between mouse and man
45. Synthesis of the CC-chemokines MIP-1α, MIP-1β, and RANTES is associated with a type 1 immune response
46. T helper 1 and T helper 2 cells respond differentially to chemokines
47. Respiratory syncytial virus infection enhances neutrophil and eosinophil adhesion to cultured respiratory epithelial cells. Roles of CD18 and intercellular adhesion molecule- 1
48. cis-acting elements that confer lung epithelial cell expression of the CC10 gene
49. Human interferon-inducible protein-10 induces mononuclear cell infiltration in mice and promotes the migration of human T lymphocytes into the peripheral tissues and human peripheral blood lymphocytes-SCID mice
50. Immunoreactive RANTES and MIP-1α are secreted into the nasal aspirates of children with virus-associated asthma
51. Eosinophil recruitment following allergen challenge is associated with the release of the chemokine RANTES into asthmatic airways
52. RANTES, macrophage-inhibitory protein 1α, and the eosinophil product major basic protein are released into upper respiratory secretions during virus-induced asthma exacerbations in children
53. Compartmentalized expression of RANTES in a murine model of endotoxemia
54. Identification of IL- 5 and RANTES as the major eosinophil chemoattractants in the asthmatic lung
55. Essential role of nuclear factor-κB in the induction of eosinophilia in allergic airway inflammation
56. The kinetics of allergen-induced transcription of messenger RNA for monocyte chemotactic protein-3 and RANTES in the skin of human atopic subjects: Relationship to eosinophil, T cell, and macrophage recruitment