Voltage-sensitive dye mapping of activation and conduction in adult mouse hearts

Annals of Biomedical Engineering

Volumn 28, Issue 8, 2000, Pages 958-967

  Nygren, A ^a   Clark, R B ^a   Belke, D D ^a   Kondo, C ^a   Giles, W R ^a   Witkowski, F X ^b  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIOVASCULAR SYSTEM; ELECTROCARDIOGRAPHY; ELECTROPHYSIOLOGY; FUNCTIONAL ELECTRIC STIMULATION;

TRANSMURAL CONDUCTION ABNORMALITIES; VENTRICLES; VOLTAGE SENSITIVE DYE;

BIOMEDICAL ENGINEERING;

1 (3 SULFONATOPROPYL) 4 (BETA)(2 (DI N BUTYLAMINO) 6 NAPHTHYLVINYL)PYRIDINIUM BETAINE; 1-(3-SULFONATOPROPYL)-4-(BETA)(2-(DI-N-BUTYLAMINO)-6-NAPHTHYLVINYL)PYRIDINIUM BETAINE; FLUORESCENT DYE; PYRIDINIUM DERIVATIVE;

ANIMAL; ARTICLE; FLUORESCENCE; HEART; HEART ATRIUM; HEART MUSCLE CONDUCTION SYSTEM; HEART PACING; HEART RATE; HEART VENTRICLE; IN VITRO STUDY; METABOLISM; MOUSE; PHYSIOLOGY; REPRODUCIBILITY; SINUS NODE;

ANIMALS; CARDIAC PACING, ARTIFICIAL; FLUORESCENCE; FLUORESCENT DYES; HEART; HEART ATRIA; HEART CONDUCTION SYSTEM; HEART RATE; HEART VENTRICLES; MICE; PYRIDINIUM COMPOUNDS; REPRODUCIBILITY OF RESULTS; SINOATRIAL NODE;

EID: 0034352166     PISSN: 00906964     EISSN: None     Source Type: Journal    
DOI: 10.1114/1.1308501     Document Type: Article

References (44)

1. Baker, L. C., B. London, B. R. Choi, G. Koren, and G. Salama. Enhanced dispersion of repolarization and refractoriness in transgenic mouse hearts promotes reentrant ventricular tachycardia. Circ. Res. 86:396-407, 2000.
2. Barry, D. M., H. Xu, R. B. Schuessler, and J. M. Nerbonne. Functional knockout of the transient outward current, long-QT syndrome, and cardiac remodeling in mice expressing a dominant-negative Kv4 alpha subunit. Circ. Res. 83:560-567, 1998.
3. Berul, C. I., M. J. Aronovitz, P. J. Wang, and M. E. Mendelsohn. In vivo cardiac electrophysiology studies in the mouse. Circulation 94:2641-2648, 1996.
4. Bharati, S., and M. Lev. Cardiac conduction system involvement in sudden death of obese young people. Am. Heart J. 129:273-281, 1995.
5. Chawla, K. K., and W. S. Harris. The atrial repolarization wave: A newly described finding in the electrocardiogram of the mouse (Mus musculus). J. Electrocardiol. 3:317-324, 1970.
6. Cheng, Y., D. R. Van Wagoner, T. N. Mazgalev, P. J. Tchou, and I. R. Efimov. Voltage-sensitive dye RH421 increases contractility of cardiac muscle. Can. J. Physiol. Pharmacol. 76:1146-1150, 1998.
7. Chien, K. R. Cardiac muscle diseases in genetically engineered mice: Evolution of molecular physiology. Am. J. Physiol. 269:H755-H766, 1995.
8. Christensen, G., Y. Wang, and K. R. Chien. Physiological assessment of complex cardiac phenotypes in genetically engineered mice. Am. J. Physiol. 272:H2513-H2524, 1997.
9. Chuck, E. T., D. M. Freeman, M. Watanabe, and D. S. Rosenbaum. Changing activation sequence in the embryonic chick heart. Implications for the development of the His-Purkinje system. Circ. Res. 81:470-476, 1997.
10. Coppen, S. R., E. Dupont, S. Rothery, and N. J. Severs. Connexin45 expression is preferentially associated with the ventricular conduction system in mouse and rat heart. Circ. Res. 82:232-243, 1998.
11. Davis, L. M., H. L. Kanter, E. C. Beyer, and J. E. Saffitz. Distinct gap junction protein phenotypes in cardiac tissues with disparate conduction properties. J. Am. Coll. Cardiol. 24:1124-1132, 1994.
12. Efimov, I. R., D. T. Huang, J. M. Rendt, and G. Salama. Optical mapping of repolarization and refractoriness from intact hearts. Circulation 90:1469-1480, 1994.
13. + current modulates repolarization and excitation-contraction coupling in adult mouse ventricle. J. Physiol. (London) 504:557-563, 1997.
14. Fishman, G. I., M. J. Vink, and D. C. Spray. Can we learn about conduction by the use of genetic approaches. In: Discontinuous Conduction in the Heart, edited by P. M. Spooner, R. W. Joyner, and J. Jalife. New York: Armonk, Futura, 1997.
15. Girouard, S. D., K. R. Laurita, and D. S. Rosenbaum. Unique properties of cardiac action potentials recorded with voltage-sensitive dyes. J. Cardiovasc. Electrophysiol. 7:1024-1038, 1996.
16. Goldbarg, A. N., H. K. Hellerstein, J. H. Bruell, and A. F. Daroczy. Electrocardiogram of the normal mouse, Mus musculus: General considerations and genetic aspects. Cardiovasc. Res. 2:93-99, 1968.
17. Gourdie, R. G., N. J. Severs, C. R. Green, S. Rothery, P. Germroth, and R. P. Thompson. The spatial distribution and relative abundance of gap-junctional connexin40 and connexin43 correlate to functional properties of components of the cardiac atrioventricular conduction system. J. Cell. Sci. 105:985-991, 1993.
18. Guerrero, P. A., R. B. Schuessler, L. M. Davis, E. C. Beyer, C. M. Johnson, K. A. Yamada, and J. E. Saffitz. Slow ventricular conduction in mice heterozygous for a connexin43 null mutation. J. Clin. Invest. 99:1991-1998, 1997.
19. James, J. F., T. E. Hewett, and J. Robbins. Cardiac physiology in transgenic mice. Circ. Res. 82:407-415, 1998.
20. Kass, D. A., J. M. Hare, and D. Georgakopoulos. Murine cardiac function: A cautionary tail. Circ. Res. 82:519-522, 1998.
21. Kirchhoff, S., E. Nelles, A. Hagendorff, O. Kruger, O. Traub, and K. Willecke. Reduced cardiac conduction velocity and predisposition to arrhythmias in connexin40-deficient mice. Curr. Biol. 8:299-302, 1998.
22. Larsen, T. S., D. D. Belke, R. Sas, W. R. Giles, D. L. Severson, G. D. Lopaschuk, and J. V. Tyberg. The isolated working mouse heart: Methodological considerations. Pflügers Arch. Euro. J. Physiol. 437:979-985, 1999.
23. Laurita, K. R., S. D. Girouard, and D. S. Rosenbaum. Modulation of ventricular repolarization by a premature stimulus. Role of epicardial dispersion of repolarization kinetics demonstrated by optical mapping of the intact guinea pig heart. Circ. Res. 79:493-503, 1996.
24. Leon, L. J., and F. X. Witkowski. Calculation of transmembrane current from extracellular potential recordings: A model study. J. Cardiovasc. Electrophysiol. 6:379-390, 1995.
25. Lev, M., and J. C. Thaemert. The conduction system of the mouse heart. Acta Anat. (Basel) 85:342-352, 1973.
26. Liu, Y., C. Cabo, R. Salomonsz, M. Delmar, J. Davidenko, and J. Jalife. Effects of diacetyl monoxime on the electrical properties of sheep and guinea pig ventricular muscle. Cardiovasc. Res. 27:1991-1997, 1993.
27. Morley, G. E., D. Vaidya, F. H. Samie, C. Lo, M. Delmar, and J. Jalife. Characterization of conduction in the ventricles of normal and heterozygous Cx43 knockout mice using optical mapping. J. Cardiovasc. Electrophysiol. 10:1361-1375, 1999.
28. Richards, A. G., E. Simonson, and M. B. Visscher. Electrocardiogram and phonogram of adult and newborn mice in normal conditions and under the effect of cooling, hypoxia, and potassium. Am. J. Physiol. 174:203-298, 1953.
29. Roberts, D. E., L. T. Hersh, and A. M. Scher. Influence of cardiac fiber orientation on wave-front voltage, conduction velocity, and tissue resistivity in the dog. Circ. Res. 44:701-712, 1979.
30. Rohr, S., and B. M. Salzberg. Characterization of impulse propagation at the microscopic level across geometrically defined expansions of excitable tissue: Multiple site optical recording of transmembrane voltage (MSORTV) in patterned growth heart cell cultures. J. Gen. Physiol. 104:287-309, 1994.
31. Rohr, S., and B. M. Salzberg. Multiple site optical recording of transmembrane voltage (MSORTV) in patterned growth heart cell cultures: Assessing electrical behavior, with microsecond resolution, on a cellular and subcellular scale. Biophys. J. 67:1301-1315, 1994.
32. Saffitz, J. E., H. L. Kanter, K. G. Green, T. K. Tolley, and E. C. Beyer. Tissue-specific determinants of anisotropic conduction velocity in canine atrial and ventricular myocardium. Circ. Res. 74:1065-1070, 1994.
33. Salama, G., D. T. Huang, and I. R. Efimov. Changes in activation and repolarization patterns during cardiac hypoxia, no-flow ischemia, and partial-flow ischemia measured with voltage-sensitive dyes and imaging techniques. Prog. Int. Union Physiol. Sci. 3:174-198, 1993.
34. Scher, A. M. The electrocardiogram. In: Textbook of Physiology, edited by H. D. Patton, A. F. Fuchs, B. Hille, A. M. Scher, and R. Steiner. Philadelphia, PA: Saunders, 1989.
35. Sellin, L. C., and J. J. McArdle. Multiple effects of 2, 3-butanedione monoxime. Pharmacol. Toxicol. 74:305-313, 1994.
36. Simon, A. M., D. A. Goodenough, and D. L. Paul. Role of Cx40 in cardiac conduction. In: Gap Junction, edited by R. Werner. Amsterdam: IOS, 1998.
37. Suzuki, J., H. Tsubone, and S. Sugano. Characteristics of ventricular activation and recovery patterns in the rat. J. Vet. Med. Sci. 54:711-716, 1992.
38. Tanaka, H., T. Sekine, K. Nishimaru, and K. Shigenobu. Role of sarcoplasmic reticulum in myocardial contraction of neonatal and adult mice. Comp. Biochem. Physiol. A Mol. Integr. Physiol. 120:431-438, 1998.
39. Thomas, S. A., R. B. Schuessler, C. I. Berul, M. A. Beardslee, E. C. Beyer, M. E. Mendelsohn, and J. E. Saffitz. Disparate effects of deficient expression of connexin43 on atrial and ventricular conduction: Evidence for chamber-specific molecular determinants of conduction. Circulation 97:686-691, 1998.
40. Vaidya, D., G. E. Morley, F. H. Samie, and J. Jalife. Reentry and fibrillation in the mouse heart. A challenge to the critical mass hypothesis. Circ. Res. 85:174-181, 1999.
41. Verheule, S., C. A. van Batenburg, F. E. Coenjaerts, S. Kirchhoff, K. Willecke, and H. J. Jongsma. Cardiac conduction abnormalities in mice lacking the gap junction protein connexin40. J. Cardiovasc. Electrophysiol. 10:1380-1389, 1999.
42. Witkowski, F. X., R. B. Clark, T. S. Larsen, A. Melnikov, and W. R. Giles. Voltage-sensitive dye recordings of electrophysiological activation in a Langendorff-perfused mouse heart. Can. J. Cardiol. 13:1077-1082, 1997.
43. Witkowski, F. X., L. J. Leon, P. A. Penkoske, R. B. Clark, M. L. Spano, W. L. Ditto, and W. R. Giles. A method for visualization of ventricular fibrillation: Design of a cooled fiberoptically coupled image intensified CCD data acquisition system incorporating wavelet shrinkage based adaptive filtering. Chaos 8:94-102, 1998.
44. Witkowski, F. X., L. J. Leon, P. A. Penkoske, W. R. Giles, M. L. Spano, W. L. Ditto, and A. T. Winfree. Spatiotemporal evolution of ventricular fibrillation. Nature (London) 392:78-82, 1998.